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The containment of epidemic spreading is a major challenge in science. Vaccination, whenever available, is the best way to prevent the spreading, because it eventually immunizes individuals. However, vaccines are not perfect, and total…

Background: To prevent future outbreaks of COVID-19, Australia is pursuing a mass-vaccination approach in which a targeted group of the population comprising healthcare workers, aged-care residents and other individuals at increased risk of…

种群与进化 · 定量生物学 2021-08-09 Cameron Zachreson , Sheryl L. Chang , Oliver M. Cliff , Mikhail Prokopenko

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

社会与信息网络 · 计算机科学 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and…

种群与进化 · 定量生物学 2022-06-28 Omar El Deeb , Maya Jalloul

Restrictions on social and economic activities, as well as vaccinations, have been a key intervention in containing the COVID-19 epidemic. Our work focuses on better understanding the options available to policymakers under the conditions…

最优化与控制 · 数学 2023-09-07 Franco Galante , Chiara Ravazzi , Michele Garetto , Emilio Leonardi

Vaccination is an important measure available for preventing or reducing the spread of infectious diseases. In this paper, an epidemic model including susceptible, infected, and imperfectly vaccinated compartments is studied on…

物理与社会 · 物理学 2015-06-15 Xiao-Long Peng , Xin-Jian Xu , Xinchu Fu , Tao Zhou

We aim to design a fairness-aware allocation approach to maximize the geographical diversity and avoid unfairness in the sense of demographic disparity. During the development of this work, the COVID-19 pandemic is still spreading in the…

最优化与控制 · 数学 2026-05-12 Hadis Anahideh , Lulu Kang , Nazanin Nezami

Controlling and understanding epidemic outbreaks has recently drawn great interest in a large spectrum of research communities. Vaccination is one of the most well-established and effective strategies in order to contain an epidemic. In the…

社会与信息网络 · 计算机科学 2023-05-29 Sourin Chatterjee , Ahad N. Zehmakan

The threat of avian influenza and the 2004-2005 influenza vaccine supply shortage in the United States has sparked a debate about optimal vaccination strategies to reduce the burden of morbidity and mortality caused by the influenza virus.…

种群与进化 · 定量生物学 2010-02-10 Shweta Bansal , Babak Pourbohloul , Lauren Ancel Meyers

Vaccination is crucial for the control of epidemics. Yet it is a social dilemma since non-vaccinators can benefit from the herd immunity created by the vaccinators. Thus the optimum vaccination level is not reached via voluntary vaccination…

种群与进化 · 定量生物学 2019-02-06 Yuting Wei , Yaosen Lin , Bin Wu

In this study, we present an immuno-epidemic model to understand mitigation options during an epidemic break. The model incorporates comorbidity and multiple-vaccine doses through a system of coupled integro-differential equations to…

种群与进化 · 定量生物学 2025-05-28 Samiran Ghosh , Malay Banerjee , Amit K Chattopadhyay

We introduce a multi-population mean field game framework to examine how economic status and authority perception shape vaccination and social distancing decisions under different epidemic control policies. We carried out a survey to inform…

最优化与控制 · 数学 2025-12-30 Huaning Liu , Junke Yang , Soren L. Larsen , Pamela P. Martinez , Gokce Dayanikli

This paper uses new and existing methods to study collective trends across countries throughout the pandemic, with a focus on the multivariate time series of reproduction numbers and vaccine proliferation. We begin with a time-varying…

物理与社会 · 物理学 2023-10-16 Nick James , Max Menzies

Although the topic of opinion polarization receives much attention from the media, public opinion researchers and political scientists, the phenomenon itself has not been adequately characterized in either the lay or academic literature. To…

物理与社会 · 物理学 2024-08-08 Hane Lee , Michael E. Sobel

A COVID-19 vaccine is our best bet for mitigating the ongoing onslaught of the pandemic. However, vaccine is also expected to be a limited resource. An optimal allocation strategy, especially in countries with access inequities and temporal…

Frequent emergence of communicable diseases has been a major concern worldwide. Lack of sufficient resources to mitigate the disease-burden makes the situation even more challenging for lower-income countries. Hence, strategy development…

种群与进化 · 定量生物学 2023-02-03 Biplab Maity , Swarnendu Banerjee , Abhishek Senapati , Joydev Chattopadhyay

During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…

种群与进化 · 定量生物学 2021-04-28 Joseph Samuel , Supurna Sinha

The recent COVID-19 pandemic highlighted the need of non-pharmaceutical interventions in the first stages of a pandemic. Among these, lockdown policies proved unavoidable yet extremely costly from an economic perspective. To better…

最优化与控制 · 数学 2021-12-14 Leonardo Cianfanelli , Francesca Parise , Daron Acemoglu , Giacomo Como , Asuman Ozdaglar

If we can lower the number of people needed to vaccinate for a community to be immune against contagious diseases, we can save resources and life. A key to reach such a lower threshold of immunization is to find and vaccinate people who,…

种群与进化 · 定量生物学 2012-10-10 Sungmin Lee , Luis E. C. Rocha , Fredrik Liljeros , Petter Holme

In this study, we formulate a mathematical model incorporating age specific transmission dynamics of COVID-19 to evaluate the role of vaccination and treatment strategies in reducing the size of COVID-19 burden. Initially, we establish the…

种群与进化 · 定量生物学 2021-02-22 Bishal Chhetri , D. k. k. Vamsi , S Balasubramanian , Carani B Sanjeevi