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By the end of 2020, a year since the first cases of infection by the Covid-19 virus have been reported, there is a light at the end of the tunnel. Several pharmaceutical companies made significant progress in developing effective vaccines…

种群与进化 · 定量生物学 2021-08-04 Hilla De-Leon , Francesco Pederiva

The COVID-19 pandemic has posed a policy making crisis where efforts to slow down or end the pandemic conflict with economic priorities. This paper provides mathematical analysis of optimal disease control policies with idealized…

最优化与控制 · 数学 2021-02-16 Aaron Z. Palmer , Zelda B. Zabinsky , Shan Liu

I develop a novel macroeconomic epidemiological agent-based model to study the impact of the COVID-19 pandemic under varying policy scenarios. Agents differ with regard to their profession, family status and age and interact with other…

理论经济学 · 经济学 2020-11-13 Patrick Mellacher

Variations in individuals' perceptions of vaccination and decision-making processes can give rise to poor vaccination coverage. The future vaccination promotion programs will benefit from understanding this heterogeneity amongst groups…

定量方法 · 定量生物学 2024-11-05 Azadeh Aghaeeyan , Mark A. Lewis , Pouria Ramazi

We present a compartmental mathematical model with demography for the spread of the COVID-19 disease, considering also asymptomatic infectious individuals. We compute the basic reproductive ratio of the model and study the local and global…

种群与进化 · 定量生物学 2020-11-17 Vasiliki Bitsouni , Nikolaos Gialelis , Ioannis G. Stratis

During the COVID-19 pandemic, there were over three million infections in Los Angeles County (LAC). To facilitate distribution when vaccines first became available, LAC set up six mega-sites for dispensing a large number of vaccines to the…

最优化与控制 · 数学 2025-02-27 Suyanpeng Zhang , Sze-chuan Suen , Han Yu , Maged Dessouky , Fernando Ordonez

Healthcare workers such as doctors and nurses are expected to be trustworthy and creditable sources of vaccine-related information. Their opinions toward the COVID-19 vaccines may influence the vaccine uptake among the general population.…

社会与信息网络 · 计算机科学 2022-11-22 Sajid Hussain Rafi Ahamed , Shahid Shakil , Hanjia Lyu , Xinping Zhang , Jiebo Luo

The COVID-19 pandemic has adversely affected US public health, resulting in over a hundred million cases and more than one million deaths. Vaccination is the key intervention against the COVID-19 pandemic. Multiple COVID-19 vaccines are now…

应用统计 · 统计学 2025-02-25 Asim K. Dey

Allocation of scarce healthcare resources under limited logistic and infrastructural facilities is a major issue in the modern society. We consider the problem of allocation of healthcare resources like vaccines to people or hospital beds…

多智能体系统 · 计算机科学 2023-03-21 Aadityan Ganesh , Prajakta Nimbhorkar , Pratik Ghosal , Vishwa Prakash HV

This paper presents a stochastic optimization model for allocating and sharing a critical resource in the case of a pandemic. The demand for different entities peaks at different times, and an initial inventory from a central agency is to…

最优化与控制 · 数学 2020-04-06 Sanjay Mehrotra , Hamed Rahimian , Masoud Barah , Fengqiao Luo , Karolina Schantz

We propose a framework for the description of the effects of vaccinations on the spreading of an epidemic disease. Different vaccines can be dosed, each providing different immunization times and immunization levels. Differences due to…

偏微分方程分析 · 数学 2024-07-23 Rinaldo M. Colombo , Mauro Garavello

We analyse the economics and epidemiology of different scenarios for a phased restart of the UK economy. Our economic model is designed to address the unique features of the COVID-19 pandemic. Social distancing measures affect both supply…

The aim of this work is to investigate the optimal vaccine sharing between two SIR centers in the presence of migration fluxes of susceptibles and infected individuals during the mumps outbreak. Optimality of the vaccine allocation means…

定量方法 · 定量生物学 2018-09-11 A. Chernov , M. Kelbert , A. Shemendyuk

Opposition to vaccination has long been a non-negligible public health phenomenon resulted from people's varied perceptions toward vaccination (e.g., vaccine-phobia). This paper investigates the voluntary vaccination behavior of a…

物理与社会 · 物理学 2019-09-04 Liqun Lu , Yanfeng Ouyang

Vaccination is widely recognized as the most effective way of immunization against many infectious diseases. However, unfounded claims about supposed side effects of some vaccines have contributed to spread concern and fear among people,…

物理与社会 · 物理学 2014-12-03 A. D. Medus , C. O. Dorso

The outbreak of a novel coronavirus causing severe acute respiratory syndrome in December 2019 has escalated into a worldwide pandemic. In this work, we propose a compartmental model to describe the dynamics of transmission of infection and…

最优化与控制 · 数学 2022-10-25 Eleni Zavrakli , Andrew Parnell , David Malone , Ken Duffy , Subhrakanti Dey

Assessing the economic impact of COVID-19 pandemic and public health policies is essential for a rapid recovery. In this paper, we analyze the impact of mobility contraction on furloughed workers and excess deaths in Italy. We provide a…

物理与社会 · 物理学 2021-03-26 Valentina Pieroni , Angelo Facchini , Massimo Riccaboni

The way diseases spread through schools, epidemics through countries, and viruses through the Internet is crucial in determining their risk. Although each of these threats has its own characteristics, its underlying network determines the…

物理与社会 · 物理学 2011-12-20 Christian M. Schneider , Tamara Mihaljev , Shlomo Havlin , Hans J. Herrmann

We consider the bi-objective problem of allocating doses of a (perfect) vaccine to an infinite-dimensional metapopulation in order to minimize simultaneously the vaccination cost and the effective reproduction number $R_e$, which is defined…

最优化与控制 · 数学 2022-12-19 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

This study presents a seasonally forced cholera model that incorporates imperfect vaccination as a control strategy. The model captures the temporal dynamics of susceptible, vaccinated, infected, and recovered individuals, as well as the…

种群与进化 · 定量生物学 2025-07-15 Eric Herrison Gyamfi