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SARS-CoV-2 is a new human coronavirus (CoV), which emerged in China in late 2019 and is responsible for the global COVID-19 pandemic that caused more than 59 million infections and 1.4 million deaths in 11 months. Understanding the origin…
We study the interplay between epidemic dynamics and human decision making for epidemics that involve reinfection risk; in particular, the susceptible-infected-susceptible (SIS) and the susceptible-infected-recovered-infected (SIRI)…
At the beginning of 2020 the world has seen the initial outbreak of COVID-19, a disease caused by SARS-CoV2 virus in China. The World Health Organization (WHO) declared this disease as a pandemic on March 11 2020. As the disease spread…
As of July, 2020, acute respiratory syndrome caused by coronavirus COVID-19 is spreading over the world and causing severe economic damages. While minimizing human contact is effective in managing the outbreak, it causes severe economic…
Holland's (1975) genetic algorithm is a minimal computer model of natural selection that made it possible to investigate the effect of manipulating specific parameters on the evolutionary process. If culture is, like biology, a form of…
At the time of writing, the ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had already resulted in more than thirty-two million cases infected and more than one million deaths worldwide.…
We propose two stochastic models for the Coronavirus pandemic. The statistical properties of the models, in particular the correlation functions and the probability density function, have duly been computed. Our models, which generalises a…
Today, we are all threatened by an unprecedented pandemic: COVID-19. How different is it from other coronaviruses? Will it be attenuated or become more virulent? Which animals may be its original host? In this study, we collected and…
Comparing how different populations have suffered under COVID-19 is a core part of ongoing investigations into how public policy and social inequalities influence the number of and severity of COVID-19 cases. But COVID-19 incidence can vary…
The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…
Public policy must confront emergencies that evolve in real time and in uncertain directions, yet little is known about the nature of policy response. Here we take the coronavirus pandemic as a global and extraordinarily consequential case,…
Phase transition theory, implemented quantitatively by thermodynamic scaling, has explained the evolution of Coronavirus extremely high contagiousness caused by a few key mutations from CoV2003 to CoV2019 identified among hundreds, as well…
A dynamical epidemic model optimized using genetic algorithm and cross validation method to overcome the overfitting problem is proposed. The cross validation procedure is applied so that available data are split into a training subset used…
The integration of machine learning methods into bioinformatics provides particular benefits in identifying how therapeutics effective in one context might have utility in an unknown clinical context or against a novel pathology. We aim to…
The world is still fighting against COVID-19, which has been lasting for more than a year. Till date, it has been a greatest challenge to human beings in fighting against COVID-19 since, the pathogen SARS-COV-2 that causes COVID-19 has…
Antigenic escape constitutes the main mechanism allowing rapidly evolving viruses to achieve endemicity. Beyond granting immune escape, empirical evidence also suggests that mutations of viruses might increase their inter-host…
The dissipation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already taken on pandemic proportions, affecting over 100 countries in a couple of weeks. The evolution of the disease and its economic impact is highly…
The SARS-CoV-2 pandemic has so far unfolded diversely across the fifty United States of America, reflected both in different time progressions of infection "waves" and in magnitudes of local infection rates. Despite a marked diversity of…
RNA virus (e.g., SARS-CoV-2) evolves in a complex manner. Studying RNA virus evolution is vital for understanding molecular evolution and medicine development. Scientists lack, however, general frameworks to characterize the dynamics of RNA…
During a public health crisis like COVID-19, individuals' adoption of protective behaviors, such as self-isolation and wearing masks, can significantly impact the spread of the disease. In the meanwhile, the spread of the disease can also…