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Major interventions have been introduced worldwide to slow down the spread of the SARS-CoV-2 virus. Large-scale lockdowns of human movements are effective in reducing the spread, but they come at a cost of significantly limited societal…

In this paper we create a compartmental, stochastic process model of SARS-CoV-2 transmission, where the process's mean and variance have distinct dynamics. The model is fit to time series data from Washington from January 2020 to March 2021…

The Covid-19 outbreak of 2020 has required many governments to develop mathematical-statistical models of the outbreak for policy and planning purposes. This work provides a tutorial on building a compartmental model using Susceptibles,…

The outbreak of the coronavirus disease 2019 (COVID-19) has now spread throughout the globe infecting over 150 million people and causing the death of over 3.2 million people. Thus, there is an urgent need to study the dynamics of…

When the novel coronavirus disease SARS-CoV2 (COVID-19) was officially declared a pandemic by the WHO in March 2020, the scientific community had already braced up in the effort of making sense of the fast-growing wealth of data gathered by…

Washing hands, social distancing and staying at home are the preventive measures set in place to contain the spread of the COVID-19, a disease caused by SARS-CoV-2. These measures, although straightforward to follow, highlight the tip of an…

COVID-19 is a new pandemic disease that is affecting almost every country with a negative impact on social life and economic activities. The number of infected and deceased patients continues to increase globally. Mathematical models can…

With the rapid spread of the novel coronavirus (COVID-19) across the globe and its continuous mutation, it is of pivotal importance to design a system to identify different known (and unknown) variants of SARS-CoV-2. Identifying particular…

In this paper we study intra-host viral adaptation by antigenic cooperation - a mechanism of immune escape that serves as an alternative to the standard mechanism of escape by continuous genomic diversification and allows to explain a…

Controlling the spread of COVID-19 - even after a licensed vaccine is available - requires the effective use of non-pharmaceutical interventions: physical distancing, limits on group sizes, mask wearing, etc. To date, such interventions…

In the 21st century, several emergent viruses have posed a global threat. Each pathogen has emphasized the value of rapid and scalable vaccine development programs. The ongoing SARS-CoV-2 pandemic has made the importance of such efforts…

In the United States, from the start of the COVID-19 pandemic to December 31, 2020, 341,199 deaths and more than 19,663,976 infections were recorded. Recent literature establishes that communities with poverty-related health problems, such…

In regard to infectious diseases socioeconomic determinants are strongly associated with differential exposure and susceptibility however they are seldom accounted for by standard compartmental infectious disease models. These associations…

The seasonal human influenza virus undergoes rapid evolution, leading to significant changes in circulating viral strains from year to year. These changes are typically driven by adaptive mutations, particularly in the antigenic epitopes,…

Various variants of the well known Covariance Matrix Adaptation Evolution Strategy (CMA-ES) have been proposed recently, which improve the empirical performance of the original algorithm by structural modifications. However, in practice it…

To investigate the origin of cooperative behaviors, we developed an evolutionary model of sequential strategies and tested our model with computer simulations. The sequential strategies represented by stochastic machines were evaluated…

The Coronavirus Disease 2019 (COVID-19) pandemic has caused tremendous amount of deaths and a devastating impact on the economic development all over the world. Thus, it is paramount to control its further transmission, for which purpose it…

Voluntary vaccination is effective to prevent infectious diseases from spreading. Both vaccination behavior and cognition of the vaccination risk play important roles in individual vaccination decision making. However, it is not clear how…

Generative adversarial networks (GAN) became a hot topic, presenting impressive results in the field of computer vision. However, there are still open problems with the GAN model, such as the training stability and the hand-design of…

In order to slow the spread of the CoViD-19 pandemic, governments around the world have enacted a wide set of policies limiting the transmission of the disease. Initially, these focused on non-pharmaceutical interventions; more recently,…