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相关论文: Robust Pandemic Control Synthesis with Formal Spec…

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During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…

种群与进化 · 定量生物学 2021-04-28 Joseph Samuel , Supurna Sinha

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

种群与进化 · 定量生物学 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

OBJECTIVES: to describe the first wave of the COVID-19 pandemic with a focus on undetected cases and to evaluate different post-lockdown scenarios. DESIGN: the study introduces a SEIR compartmental model, taking into account the…

种群与进化 · 定量生物学 2021-06-03 Nicola Picchiotti , Monica Salvioli , Elena Zanardini , Francesco Missale

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

应用统计 · 统计学 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

最优化与控制 · 数学 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

The COVID-19 pandemic has forced policy makers to decree urgent confinements to stop a rapid and massive contagion. However, after that stage, societies are being forced to find an equilibrium between the need to reduce contagion rates and…

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

种群与进化 · 定量生物学 2021-08-17 Evangelos F. Magirou

In this paper, we develop a robust economic model predictive controller for the containment of stochastic Susceptible-Exposed-Infected-Vigilant (SEIV) epidemic processes which drives the process to extinction quickly, while minimizing the…

最优化与控制 · 数学 2019-05-14 Nicholas J. Watkins , Cameron Nowzari , George J. Pappas

Game theory has been an effective tool in the control of disease spread and in suggesting optimal policies at both individual and area levels. In this paper, we propose a multi-region SEIR model based on stochastic differential game theory,…

最优化与控制 · 数学 2021-03-10 Yao Xuan , Robert Balkin , Jiequn Han , Ruimeng Hu , Hector D. Ceniceros

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

种群与进化 · 定量生物学 2021-05-18 G. Albi , L. Pareschi , M. Zanella

The synthetic control method is an empirical methodology forcausal inference using observational data. By observing thespread of COVID-19 throughout the world, we analyze the dataon the number of deaths and cases in different regions…

计算机与社会 · 计算机科学 2020-09-29 Niloofar Bayat , Cody Morrin , Yuheng Wang , Vishal Misra

We propose a stochastic SIR model, specified as a system of stochastic differential equations, to analyse the data of the Italian COVID-19 epidemic, taking also into account the under-detection of infected and recovered individuals in the…

种群与进化 · 定量生物学 2021-02-22 Sara Pasquali , Antonio Pievatolo , Antonella Bodini , Fabrizio Ruggeri

This study aims to determine an optimal control strategy for vaccine scheduling in COVID-19 pandemic treatment by converting widely acknowledged infectious disease model named SEIR into an optimal control problem. The problem is augmented…

种群与进化 · 定量生物学 2020-08-26 Syed Irfan Ali Meerza , Seyed M. Karimi , Bert B. Little , Jacek M. Zurada , Tamer Inanc

The purpose of this work is to give a contribution to the understanding of the COVID-19 contagion in Italy. To this end, we developed a modified Susceptible-Infected-Recovered (SIR) model for the contagion, and we used official data of the…

物理与社会 · 物理学 2020-04-01 Giuseppe C. Calafiore , Carlo Novara , Corrado Possieri

Restrictions on social and economic activities, as well as vaccinations, have been a key intervention in containing the COVID-19 epidemic. Our work focuses on better understanding the options available to policymakers under the conditions…

最优化与控制 · 数学 2023-09-07 Franco Galante , Chiara Ravazzi , Michele Garetto , Emilio Leonardi

Although modeling studies are focused on the control of SIR-based systems describing epidemic data sets (particularly the COVID-19), few of them present a formal dynamic characterization in terms of equilibrium sets and stability. Such…

最优化与控制 · 数学 2021-06-03 A. H. González , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas

The COVID-19 pandemic is the profoundest health crisis of the 21rst century. The SARS-CoV-2 virus arrived in Brazil around March, 2020 and its social and economical backlashes are catastrophic. In this paper, it is investigated how Model…

COVID-19--a viral infectious disease--has quickly emerged as a global pandemic infecting millions of people with a significant number of deaths across the globe. The symptoms of this disease vary widely. Depending on the symptoms an…

种群与进化 · 定量生物学 2020-07-23 Madhab Barman , Snigdhashree Nayak , Manoj K. Yadav , Soumyendu Raha , Nachiketa Mishra

The Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model is one of the standard models of disease spreading. Here we analyse an extended SEIR model that accounts for asymptomatic carriers, believed to play an important role…

种群与进化 · 定量生物学 2021-01-26 Arghya Das , Abhishek Dhar , Srashti Goyal , Anupam Kundu , Saurav Pandey

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

种群与进化 · 定量生物学 2026-03-31 J. Ilnytskyi , T. Patsahan