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We study an optimal control problem for a non-autonomous SEIRS model with incidence given by a general function of the infective, the susceptible and the total population, and with vaccination and treatment as control variables. We prove…

最优化与控制 · 数学 2018-06-13 Joaquim P. Mateus , Paulo Rebelo , Silvério Rosa , César M. Silva , Delfim F. M. Torres

SIR models, also with age structure, can be used to describe the evolution of an infective disease. A vaccination campaign influences this dynamics immunizing part of the susceptible individuals, essentially turning them into recovered…

偏微分方程分析 · 数学 2019-10-17 Rinaldo M. Colombo , Mauro Garavello

We introduce a policy model coupled with the susceptible-infected-recovered (SIR) epidemic model to study interactions between policy-making and the dynamics of epidemics. We consider both single-region policies, as well as game-theoretic…

最优化与控制 · 数学 2024-08-06 Xia Li , Andrea L. Bertozzi , P. Jeffrey Brantingham , Yevgeniy Vorobeychik

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

最优化与控制 · 数学 2016-12-28 Olga Klimenkova

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

种群与进化 · 定量生物学 2021-08-17 Evangelos F. Magirou

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

种群与进化 · 定量生物学 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

最优化与控制 · 数学 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

最优化与控制 · 数学 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

In this research paper we modify a classical SIR model to better adapt to the dynamics of COVID-19, that is we propose the heterogeneous SQAIRD model where COVID-19 spreads over a population of economic agents, namely: the elderly, adults…

最优化与控制 · 数学 2021-05-19 Elena Gubar , Laura Policardo , Edgar J. Sanchez Carrera , Vladislav Taynitskiy

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

系统与控制 · 电气工程与系统科学 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

种群与进化 · 定量生物学 2020-06-09 Evangelos Magirou

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

种群与进化 · 定量生物学 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

The SEIR model is a compartmental model used to simulate the dynamics of an epidemic. In this chapter, we introduce two control functions in the compartmental SEIR model representing vaccination and plasma transfusion. Optimal control…

最优化与控制 · 数学 2021-07-23 Juliana Couras , Ivan Area , Juan J. Nieto , Cristiana J. Silva , Delfim F. M. Torres

A probabilistic approach to the epidemic evolution on realistic social-contact networks allows for characteristic differences among subjects, including the individual number and structure of social contacts, and the heterogeneity of the…

社会与信息网络 · 计算机科学 2022-02-11 Jan B. Broekaert , Davide La Torre , Faizal Hafiz

A linearization-based feedback-control strategy for a SEIR epidemic model is discussed. The vaccination objective is the asymptotically tracking of the removed-by-immunity population to the total population while achieving simultaneously…

动力系统 · 数学 2011-03-24 M. De la Sen , A. Ibeas , S. Alonso-Quesada

This paper presents a simple continuous-time linear vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total…

动力系统 · 数学 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

We propose and study a compartmental model for epidemiology with human behavioral effects. Specifically, our model incorporates governmental prevention measures aimed at lowering the disease infection rate, but we split the population into…

系统与控制 · 电气工程与系统科学 2026-02-16 Chloe Ngo , Christian Parkinson , Weinan Wang

Contagious diseases can spread quickly in human populations, either through airborne transmission or if some other spreading vectors are abundantly accessible. They can be particularly devastating if the impact on individuals' health has…

物理与社会 · 物理学 2022-07-20 Bram A. Siebert , James P. Gleeson , M. Asllani

Without vaccines and treatments, societies must rely on non-pharmaceutical intervention strategies to control the spread of emerging diseases such as COVID-19. Though complete lockdown is epidemiologically effective, because it eliminates…

种群与进化 · 定量生物学 2021-01-08 Jason Hindes , Simone Bianco , Ira B. Schwartz

Social distancing strategies have been adopted by governments to manage the COVID-19 pandemic, since the first outbreak began. However, further epidemic waves keep out the return of economic and social activities to their standard levels of…

最优化与控制 · 数学 2021-06-07 J. E. Sereno , A. D' Jorge , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez
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