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This work is devoted to study of a class of elliptic singular perturbed systems and their singular limit to a phase segregating system. We prove existence and uniqueness and study the asymptotic behaviour with convergence to a limiting…

偏微分方程分析 · 数学 2019-01-28 Farid Bozorgnia , Martin Burger

The work is devoted to the construction of the asymptotic behavior of the solution of a singularly perturbed system of equations of parabolic type, in the case when the limit equation has a regular singularity as the small parameter tends…

偏微分方程分析 · 数学 2020-09-17 Asan Omuraliev , Peiil Esengul Kyzy

The ability of a cell to communicate with its environment is essential for key cellular functions like replication, metabolism, or cell fate decisions. The involved molecular mechanisms are highly dynamic and difficult to capture…

人机交互 · 计算机科学 2025-09-11 Lena Cibulski , Fiete Haack , Adelinde Uhrmacher , Stefan Bruckner

We study the free boundary of solutions to the parabolic obstacle problem with fully nonlinear diffusion. We show that the free boundary splits into a regular and a singular part: near regular points the free boundary is $C^\infty$ in space…

偏微分方程分析 · 数学 2022-09-12 Alessandro Audrito , Teo Kukuljan

We address nonautonomous initial boundary value problems for decoupled linear first-order one-dimensional hyperbolic systems, investigating the phenomenon of finite time stabilization. We establish sufficient and necessary conditions…

偏微分方程分析 · 数学 2025-12-10 Irina Kmit , Natalya Lyul'ko

We consider a free boundary model of epithelial cell migration with logistic growth and nonlinear diffusion induced by mechanical interactions. Using numerical simulations, phase plane and perturbation analysis, we find and analyse…

斑图形成与孤子 · 物理学 2020-10-05 Ryan J Murphy , Pascal R Buenzli , Ruth E Baker , Matthew J Simpson

This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…

偏微分方程分析 · 数学 2025-11-11 Aesol Jeon , Ki-Ahm Lee

In this paper we establish the exact growth of the solution of the singular quasilinear p-parabolic obstacle problem near the free boundary from which we deduce its porosity.

偏微分方程分析 · 数学 2015-09-01 Abdeslem Lyaghfouri

We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…

偏微分方程分析 · 数学 2017-07-21 Tang Quoc Bao , Klemens Fellner , Evangelos Latos

We study a free boundary problem modelling the growth of non-necrotic tumors with fluid-like tissues. The fluid velocity satisfies Stokes equations with a source determined by the proliferation rate of tumor cells which depends on the…

偏微分方程分析 · 数学 2008-06-10 Junde Wu , Shangbin Cui

We consider the finite-time stabilization of homogeneous quasilinear hyperbolic systems with one side controls and with nonlinear boundary condition at the other side. We present time-independent feedbacks leading to the finite-time…

最优化与控制 · 数学 2020-05-28 Jean-Michel Coron , Hoai-Minh Nguyen

Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…

偏微分方程分析 · 数学 2023-11-01 Xu'an Dou , Chengfeng Shen , Zhennan Zhou

Reaction-diffusion models with nonlocal constraints naturally arise as limiting cases of coupled bulk-surface models of intracellular signalling. In this paper, a minimal, mass-conserving model of cell-polarization on a curved membrane is…

斑图形成与孤子 · 物理学 2022-10-04 Pearson W. Miller , Daniel Fortunato , Matteo Novaga , Stanislav Y. Shvartsman , Cyrill B. Muratov

In this paper we consider a free boundary tumor growth model with a time delay in cell proliferation and study how time delay affects the stability and the size of the tumor. The model is a coupled system of an elliptic equation, a…

偏微分方程分析 · 数学 2019-08-20 Xinyue Evelyn Zhao , Bei Hu

The dynamical and stationary behaviors of a fourth-order evolution equation with clamped boundary conditions and a singular nonlocal reaction term, which is coupled to an elliptic free boundary problem on a non-smooth domain, are…

偏微分方程分析 · 数学 2013-08-29 Philippe Laurencot , Christoph Walker

The parabolic obstacle problem for the fractional Laplacian naturally arises in American option models when the assets prices are driven by pure jump L\'evy processes. In this paper we study the regularity of the free boundary. Our main…

偏微分方程分析 · 数学 2016-05-03 Begoña Barrios , Alessio Figalli , Xavier Ros-Oton

The source term in a reaction-diffusion system, in general, does not involve explicit time dependence. A class of self-limiting growth models dealing with animal and tumor growth and bacterial population in a culture, on the other hand are…

生物物理 · 物理学 2009-11-07 Sandip Kar , Suman Kumar Banik , Deb Shankar Ray

We study the 6-vertex model with fixed boundary conditions. In the thermodynamical limit there is a formation of the limit shape. We collect most of the known results about the analytical properties of the free energy of the model as the…

数学物理 · 物理学 2010-10-26 K. Palamarchuk , N. Reshetikhin

We investigate the use of an extension of rule-based modelling for cellular signalling to create a structured space of model variants. This enables the incremental development of rule sets that start from simple mechanisms and which, by a…

其他计算机科学 · 计算机科学 2009-11-16 Russ Harmer

Communication between single cells or higher organisms by means of diffusive compounds is an important phenomenon in biological systems. Modelling therefore often occurs, most straightforwardly by a diffusion equation with suitable flux…

偏微分方程分析 · 数学 2025-05-19 Xiao Yang , Qiyao Peng , Sander C. Hille