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In this paper, we derive the minimum-energy periodic control that entrains an ensemble of structurally similar neural oscillators to a desired frequency. The state space representation of a nominal oscillator is reduced to a phase model by…

神经元与认知 · 定量生物学 2012-02-24 Anatoly Zlotnik , Jr-Shin Li

In this paper, we study the optimal control of phase models for spiking neuron oscillators. We focus on the design of minimum-power current stimuli that elicit spikes in neurons at desired times. We furthermore take the charge-balanced…

最优化与控制 · 数学 2015-03-19 Isuru Dasanayake , Jr-Shin Li

We apply the framework of optimal nonlinear control to steer the dynamics of a whole-brain network of FitzHugh-Nagumo oscillators. Its nodes correspond to the cortical areas of an atlas-based segmentation of the human cerebral cortex, and…

神经元与认知 · 定量生物学 2021-09-08 Teresa Chouzouris , Nicolas Roth , Caglar Cakan , Klaus Obermayer

In this article, we study optimal control problems of spiking neurons whose dynamics are described by a phase model. We design minimum-power current stimuli (controls) that lead to targeted spiking times of neurons, where the cases with…

动力系统 · 数学 2010-11-18 Isuru Dasanayake , Jr-Shin Li

In this paper, we investigate the fundamental limits on how the inter- spike time of a neuron oscillator can be perturbed by the application of a bounded external control input (a current stimulus) with zero net electric charge…

最优化与控制 · 数学 2012-11-20 Isuru S. Dasanayake , Jr-Shin Li

We examine the response of type II excitable neurons to trains of synaptic pulses, as a function of the pulse frequency and amplitude. We show that the resonant behavior characteristic of type II excitability, already described for harmonic…

神经元与认知 · 定量生物学 2015-06-26 Pablo Balenzuela , Javier M. Buldu , Marcos Casanova , Jordi Garcia-Ojalvo

Spatiotemporal patterns such as traveling waves are frequently observed in recordings of neural activity. The mechanisms underlying the generation of such patterns are largely unknown. Previous studies have investigated the existence and…

神经元与认知 · 定量生物学 2022-09-16 Johanna Senk , Karolína Korvasová , Jannis Schuecker , Espen Hagen , Tom Tetzlaff , Markus Diesmann , Moritz Helias

In various neurological disorders spatio-temporal excitation patterns constitute examples of excitable behavior emerging from pathological pathways. During migraine, seizure, and stroke an initially localized pathological state can…

斑图形成与孤子 · 物理学 2007-09-27 Markus A. Dahlem , Felix M. Schneider , Eckehard Schoell

In this work we study the detection of weak stimuli by spiking neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present…

神经元与认知 · 定量生物学 2009-06-04 Jorge F. Mejias , Joaquin J. Torres

Neurons in the nervous system convey information to higher brain regions by the generation of spike trains. An important question in the field of computational neuroscience is how these sensory neurons encode environmental information in a…

神经元与认知 · 定量生物学 2013-09-13 Alex Susemihl , Ron Meir , Manfred Opper

Synchronization of oscillations is a phenomenon prevalent in natural, social, and engineering systems. Controlling synchronization of oscillating systems is motivated by a wide range of applications from neurological treatment of…

最优化与控制 · 数学 2015-03-19 Jr-Shin Li , Isuru Dasanayake , Justin Ruths

We study the dynamics of a low-dimensional system of coupled model neurons as a step towards understanding the vastly complex network of neurons in the brain. We analyze the bifurcation structure of a system of two model neurons with…

动力系统 · 数学 2019-03-27 Elizabeth N. Davison , Zahra Aminzare , Biswadip Dey , Naomi Ehrich Leonard

Electrical brain stimulation relies on externally applied currents to modulate neural activity, but safety constraints require each stimulation cycle to be charge-balanced, enforcing a zero net injected charge. However, how such…

系统与控制 · 电气工程与系统科学 2025-12-09 Yuzhen Qin , Zonglin Liu , Marcel van Gerven

A single neuron is known to generate almost identical spike trains when the same fluctuating input is repeatedly applied. Here, we study the reliability of spike firing in a pulse-coupled network of oscillator neurons receiving fluctuating…

适应与自组织系统 · 物理学 2015-05-13 Jun-nosuke Teramae , Tomoki Fukai

We investigate the performance of sparsely-connected networks of integrate-and-fire neurons for ultra-short term information processing. We exploit the fact that the population activity of networks with balanced excitation and inhibition…

神经元与认知 · 定量生物学 2007-05-23 Julien Mayor , Wulfram Gerstner

While most models of randomly connected networks assume nodes with simple dynamics, nodes in realistic highly connected networks, such as neurons in the brain, exhibit intrinsic dynamics over multiple timescales. We analyze how the…

无序系统与神经网络 · 物理学 2019-09-11 Samuel P. Muscinelli , Wulfram Gerstner , Tilo Schwalger

Dynamical balance of excitation and inhibition is usually invoked to explain the irregular low firing activity observed in the cortex. We propose a robust nonlinear balancing mechanism for a random network of spiking neurons, which works…

无序系统与神经网络 · 物理学 2025-05-29 Antonio Politi , Alessandro Torcini

Recent experimental studies of living neural networks reveal that their global activation induced by electrical stimulation can be explained using the concept of bootstrap percolation on a directed random network. The experiment consists in…

概率论 · 数学 2015-05-14 Hamed Amini

In computer simulations of spiking neural networks, often it is assumed that every two neurons of the network are connected by a probability of 2\%, 20\% of neurons are inhibitory and 80\% are excitatory. These common values are based on…

神经元与认知 · 定量生物学 2015-03-06 Hamed Seyed-allaei

The mathematical theory of pattern formation in electrically coupled networks of excitable neurons forced by small noise is presented in this work. Using the Freidlin-Wentzell large deviation theory for randomly perturbed dynamical systems…

斑图形成与孤子 · 物理学 2012-06-05 Georgi S. Medvedev , Svitlana Zhuravytska
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