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We prove the following. For each weakly reversible mass-action system, there exists a positive steady state in each positive stoichiometric class.

动力系统 · 数学 2022-09-14 Balázs Boros

A reaction network together with a choice of rate constants uniquely gives rise to a system of differential equations, according to the law of mass-action kinetics. On the other hand, different networks can generate the same dynamical…

动力系统 · 数学 2021-05-18 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

We show that there exists endotactic and strongly endotactic dynamical systems that are not weakly reversible and possess infinitely many steady states. We provide a few examples in two dimensions and an example in three dimensions that…

动力系统 · 数学 2023-03-16 Samay Kothari , Abhishek Deshpande

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction…

动力系统 · 数学 2020-01-01 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

A natural condition on the structure of the underlying chemical reaction network, namely weak reversibility, is shown to guarantee the existence of an equilibrium (steady state) in each positive stoichiometric compatibility class for the…

定量方法 · 定量生物学 2011-11-14 Jian Deng , Christopher Jones , Martin Feinberg , Adrian Nachman

We give a new proof of the fact that each weakly reversible mass-action system with a single linkage class is permanent.

动力系统 · 数学 2022-09-14 Balázs Boros , Josef Hofbauer

Given a dynamical system with polynomial right-hand side, can it be generated by a reaction network that possesses certain properties? This question is important because some network properties may guarantee specific dynamical properties,…

动力系统 · 数学 2023-03-17 Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

It has been known for nearly a decade that deterministically modeled reaction networks that are weakly reversible and consist of a single linkage class have trajectories that are bounded from both above and below by positive constants (so…

概率论 · 数学 2020-01-17 David F. Anderson , Daniele Cappelletti , Jinsu Kim

Mass-action kinetics is frequently used in systems biology to model the behaviour of interacting chemical species. Many important dynamical properties are known to hold for such systems if they are weakly reversible and have a low…

动力系统 · 数学 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Mass-action chemical reaction systems are frequently used in Computational Biology. The corresponding polynomial dynamical systems are often large (consisting of tens or even hundreds of ordinary differential equations) and poorly…

动力系统 · 数学 2011-07-13 Mercedes Perez Millan , Alicia Dickenstein , Anne Shiu , Carsten Conradi

We establish that mass conserving single terminal-linkage networks of chemical reactions admit positive steady states regardless of network deficiency and the choice of reaction rate constants. This result holds for closed systems without…

分子网络 · 定量生物学 2015-03-19 Santiago Akle , Onkar Dalal , Ronan M. T. Fleming , Michael Saunders , Nicole Taheri , Yinyu Ye

Systems of differential equations with polynomial right-hand sides are very common in applications. On the other hand, their mathematical analysis is very challenging in general, due to the possibility of complex dynamics: multiple basins…

动力系统 · 数学 2022-05-31 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

The mass-based Maxwell-Stefan approach to one-phase multicomponent reactive mixtures is mathematically analyzed. It is shown that the resulting quasilinear, strongly coupled reaction-diffusion system is locally well-posed in an…

偏微分方程分析 · 数学 2014-01-09 Martin Herberg , Martin Meyries , Jan Prüss , Mathias Wilke

We prove that if a given reaction network $\mathcal{N}$ has a weakly reversible deficiency zero realization for all choice of rate constants, then there exists a $\textit{unique}$ weakly reversible deficiency zero network $\mathcal{N}'$…

分子网络 · 定量生物学 2025-02-26 Neal Buxton , Gheorghe Craciun , Abhishek Deshpande , Casian Pantea

The Deficiency-One Theorem states that there exists a unique positive steady state in each positive stoichiometric class for weakly reversible deficiency-one mass action systems with one linkage class (regardless of the values of the rate…

动力系统 · 数学 2022-09-14 Balázs Boros

Systems of differential equations with polynomial right-hand sides are very common in applications. In particular, when restricted to the positive orthant, they appear naturally (according to the law of mass-action kinetics) in ecology,…

动力系统 · 数学 2023-03-06 Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

This paper is concerned with the dynamical properties of deterministically modeled chemical reaction systems with mass-action kinetics. Such models are ubiquitously found in chemistry, population biology, and the burgeoning field of systems…

动力系统 · 数学 2011-06-20 David F. Anderson

Persistence and permanence are properties of dynamical systems that describe the long-term behavior of the solutions, and in particular specify whether positive solutions approach the boundary of the positive orthant. Mass-action systems…

动力系统 · 数学 2011-03-03 Gheorghe Craciun , Fedor Nazarov , Casian Pantea

Much attention has been focused in recent years on the following algebraic problem arising from applications: which chemical reaction networks, when taken with mass-action kinetics, admit multiple positive steady states? The interest behind…

动力系统 · 数学 2018-06-06 Anne Shiu , Timo de Wolff

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics. The original problem…

动力系统 · 数学 2011-07-05 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza
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