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The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…

种群与进化 · 定量生物学 2026-03-24 Zahra Ghadiri , Jari Saramäki , Takayuki Hiraoka

This paper is concerned with a nonlocal dispersal susceptible-infected-susceptible (SIS) epidemic model with Dirichlet boundary condition, where the rates of disease transmission and recovery are assumed to be spatially heterogeneous. We…

偏微分方程分析 · 数学 2016-01-21 Fei-Ying Yang , Wan-Tong Li

In this paper, we study a reaction-diffusion vector-host epidemic model. We define the basic reproduction number $R_0$ and show that $R_0$ is a threshold parameter: if $R_0\le 1$ the disease free steady state is globally stable; if $R_0>1$…

偏微分方程分析 · 数学 2018-12-05 Pierre Magal , G. F. Webb , Yixiang Wu

This article is concerned with a nonlocal dispersal susceptible-infected-susceptible (SIS) epidemic model with Neumann boundary condition, where the rates of disease transmission and recovery are assumed to be spatially heterogeneous and…

偏微分方程分析 · 数学 2016-01-21 Fei-Ying Yang , Wan-Tong Li , Liang Zhang

This paper is devoted to the study of asymptotic behavior of the basic reproduction ratio for periodic reaction-diffusion systems in the case of small and large diffusion coefficients. We first establish the continuity of the basic…

偏微分方程分析 · 数学 2020-09-14 Lei Zhang , Xiao-Qiang Zhao

An important issue in theoretical epidemiology is the epidemic threshold phenomenon, which specify the conditions for an epidemic to grow or die out. In standard (mean-field-like) compartmental models the concept of the basic reproductive…

生物物理 · 物理学 2007-05-23 D. Alves , V. J. Haas , A. Caliri

The basic reproduction ratio is a crucial threshold parameter in infectious disease models. In nonlocal dispersal systems, its variational characterization is challenging due to the possible absence of a principal eigenvalue caused by…

偏微分方程分析 · 数学 2026-05-27 Xiandong Lin , Jiazhuo Cheng , Qiru Wang

This paper is devoted to the study of the asymptotic behavior of the principal eigenvalue and basic reproduction ratio associated with periodic population models in a patchy environment for small and large dispersal rates. We first deal…

经典分析与常微分方程 · 数学 2021-08-04 Lei Zhang , Xiao-Qiang Zhao

We show we can control an epidemic reaction-diffusion on a directed, and heterogeneous, network by redirecting the flows, thanks to the optimisation of well-designed loss functions, in particular the basic reproduction number of the model.…

动力系统 · 数学 2022-02-07 Pierre-Yves Massé , Quentin Laborde , Maria Cherifa , Jules Olayé , Laurent Oudre

This paper deals with a simplified SIS model, which describes the transmission of the disease in time-periodic heterogeneous environment. To understand the impact of spatial heterogeneity of environment and small advection on the…

偏微分方程分析 · 数学 2015-10-14 Jing Ge , Chengxia Lei , Zhigui Lin

The basic reproductive number -- $R_0$ -- is one of the most common and most commonly misapplied numbers in public health. Although often used to compare outbreaks and forecast pandemic risk, this single number belies the complexity that…

种群与进化 · 定量生物学 2020-04-15 Laurent Hébert-Dufresne , Benjamin M. Althouse , Samuel V. Scarpino , Antoine Allard

Reproduction numbers are widely used for the estimation and prediction of epidemic spreading processes over networks. However, reproduction numbers do not enable estimation and prediction in individual communities within networks, and they…

系统与控制 · 电气工程与系统科学 2025-06-23 Baike She , Philip E. Paré , Matthew Hale

We show that the basic reproduction number of an SIS patch model with standard incidence is either strictly decreasing and strictly convex with respect to the diffusion coefficient of infected subpopulation if the patch reproduction numbers…

种群与进化 · 定量生物学 2020-01-03 Daozhou Gao , Chao-Ping Dong

The purpose of this paper is to investigate the principal spectral theory and asymptotic behavior of the spectral bound for cooperative nonlocal dispersal systems, specifically focusing on the case where partial diffusion coefficients are…

经典分析与常微分方程 · 数学 2024-09-26 Lei Zhang

Accurate estimates of the reproduction ratio are crucial to project infectious disease epidemic evolution and guide public health response. Here, we prove that estimates of the reproduction ratio based on inference from surveillance data…

物理与社会 · 物理学 2025-01-08 Piero Birello , Michele Re Fiorentin , Boxuan Wang , Vittoria Colizza , Eugenio Valdano

When an infectious disease strikes a population, the number of newly reported cases is often the only available information that one can obtain during early stages of the outbreak. An important goal of early outbreak analysis is to obtain a…

定量方法 · 定量生物学 2013-05-30 Bahman Davoudi , Babak Pourbohloul , Joel Miller , Rafael Meza , Lauren Ancel Meyers , David J. D. Earn

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

定量方法 · 定量生物学 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

概率论 · 数学 2011-12-21 Tom Britton , David Lindenstrand

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

种群与进化 · 定量生物学 2017-09-05 Kristoffer Spricer , Pieter Trapman

Accurate epidemic forecasting requires models that account for the layered and heterogeneous nature of real social interactions. The basic reproduction number $\mathcal R_0$ calculated from models that assume homogeneous mixing or…

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