相关论文: Agent-Based Simulation of the Two-Dimensional Patl…
The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions…
This paper aims to develop numerical approximations of the Keller--Segel equations that mimic at the discrete level the lower bounds and the energy law of the continuous problem. We solve these equations for two unknowns: the organism (or…
In this paper we investigate the one-dimensional parabolic-parabolic Patlak-Keller-Segel model of chemotaxis. For the case when the diffusion coefficient of chemical substance is equal to two, in terms of travelling wave variables the…
We study a stochastic particle system with a logarithmically-singular inter-particle interaction potential which allows for inelastic particle collisions. We relate the squared Bessel process to the evolution of localized clusters of…
Chemotaxis systems of Keller--Segel type constitute one of the central mathematical frameworks for understanding aggregation phenomena in biological and ecological systems. Over the past decades, the theory has evolved from the classical…
We introduce a stochastic system of interacting particles which is expected to furnish as the number of particles goes to infinity a stochastic approach of the 2-D Keller-Segel model. In this note, we prove existence and some uniqueness for…
A Keller-Segel model describes macroscopic dynamics of bacterial colonies and biological cells. Bacteria secret chemical which attracts other bacteria so that they move towards chemical gradient creating nonlocal attraction between…
The Cellular Potts Model (CPM) has been used for simulating various biological phenomena such as differential adhesion, fruiting body formation of the slime mold Dictyostelium discoideum, angiogenesis, cancer invasion, chondrogenesis in…
We analyse an operator arising in the description of singular solutions to the two-dimensional Keller-Segel problem. It corresponds to the linearised operator in parabolic self-similar variables, close to a concentrated stationary state.…
We consider the parabolic-elliptic Patlak-Keller-Segel (PKS) model of chemotactic aggregation in two space dimensions which describes the aggregation of bacteria under chemo-taxis. When the mass is equal to $8\pi$ and the second moment is…
We consider a special case of the Patlak-Keller-Segel system in a disc, which arises in the modelling of chemotaxis phenomena. For a critical value of the total mass, the solutions are known to be global in time but with density becoming…
We study the Keller-Segel model of chemotaxis and develop a composite particle-grid numerical method with adaptive time stepping which allows us to accurately resolve singular solutions. The numerical findings (in two dimensions) are then…
Stochastic agent-based models can account for millions of cells with spatiotemporal movement that can be a function of different factors. However, these simulations can be computationally expensive. In this work, we develop a novel…
We investigate the (reduced) Keller-Segel equations modeling chemotaxis of bio-organisms. We present a formal derivation and partial rigorous results of the blowup dynamics of solution of these equations describing the chemotactic…
The Keller-Segel-Navier-Stokes system governs chemotaxis in liquid environments. This system is to be solved for the organism and chemoattractant densities and for the fluid velocity and pressure. It is known that if the total initial cell…
In this paper, we analyze the behavior of a multi-agent system driven by the interactions of agents within a competitive environment. To achieve this, we describe the transition probabilities that underlie the system's stochastic nature. We…
We develop and analyse a discrete, one-dimensional model of cell motility which incorporates the effects of volume filling, cell-to-cell adhesion and chemotaxis. The formal continuum limit of the model is a nonlinear generalisation of the…
Agent-based modelling is a valuable approach for systems whose behaviour is driven by the interactions between distinct entities. They have shown particular promise as a means of modelling crowds of people in streets, public transport…
A hybrid stochastic individual-based model of proliferating cells with chemotaxis is presented. The model is expressed by a branching diffusion process coupled to a partial differential equation describing concentration of a chemotactic…
This article proposes a methodology to model and simulate complex systems, based on IRM4MLS, a generic agent-based meta-model able to deal with multi-level systems. This methodology permits the engineering of dynamic multi-level agent-based…