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The microvascular networks in the body of vertebrates consist of the smallest vessels such as arterioles, capillaries, and venules. The flow of RBCs through these networks ensures the gas exchange in as well as the transport of nutrients to…

生物物理 · 物理学 2021-02-26 A. Kihm , S. Quint , M. W. Laschke , M. D. Menger , T. John , L. Kaestner , C. Wagner

One-dimensional blood flow models take the general form of nonlinear hyperbolic systems but differ greatly in their formulation. One class of models considers the physically conserved quantities of mass and momentum, while another class…

流体动力学 · 物理学 2016-04-19 Charles Puelz , Suncica Canic , Beatrice Riviere , Craig G. Rusin

This study introduces an open-source computational framework for the generation and permeability evaluation of synthetic porous media. The proposed methodology integrates crystallographic and meshing tools to construct controlled…

组织与器官 · 定量生物学 2025-02-21 Thomas Lavigne , Camilo Andrés Suarez Afanador , Anas Obeidat , Stéphane Urcun

Modelling the sudden depressurisation of superheated liquids through nozzles is a challenge because the pressure drop causes rapid flash boiling of the liquid. The resulting jet usually demonstrates a wide range of structures, including…

流体动力学 · 物理学 2021-12-15 David Schmidt , Romit Maulik , Konstantinos G. Lyras

Systems comprising a turbulent channel flow overlaying a permeable bed can be found in a variety of industrial and natural applications (e.g. urban planning, fracking, submerged vegetation). One important realization of this system is at…

流体动力学 · 物理学 2017-08-01 Benjamin H. Sonin

A new two-dimensional model for blood flows in arteries with arbitrary cross sections is derived. The model consists of a system of balance laws for conservation of mass and balance of momentum in the axial and angular directions. The…

数值分析 · 数学 2021-08-23 Cesar Alberto Rosales-Alcantar , Gerardo Hernandez-Duenas

In this paper, we extend the Darcy law for micropolar fluid flow in a thin porous medium. This provides a framework for understanding how a fluid's microstructural properties, the geometry of the porous medium and the thickness of the…

偏微分方程分析 · 数学 2025-08-07 María Anguiano , Francisco J. Suárez-Grau

We propose simple methods for multivariate diffusion bridge simulation, which plays a fundamental role in simulation-based likelihood and Bayesian inference for stochastic differential equations. By a novel application of classical coupling…

统计理论 · 数学 2014-06-02 Mogens Bladt , Samuel Finch , Michael Sørensen

The blood vascular system consists of blood vessels such as arteries, arterioles, capillaries and veins that convey blood throughout the body. The pressure difference which exists between the ends of the vessels provides the living force…

组织与器官 · 定量生物学 2020-04-21 Tahmineh Azizi , Robert Mugabi

We investigate the margination of microparticles/platelets in blood flow through complex geometries typical for in vivo vessel networks: a vessel confluence and a bifurcation. Using 3D Lattice-Boltzmann simulations, we confirm that behind…

生物物理 · 物理学 2018-08-15 C. Bächer , A. Kihm , L. Schrack , L. Kaestner , M. W. Laschke , C. Wagner , S. Gekle

Two-scale models pose a promising approach in simulating reactive flow and transport in evolving porous media. Classically, homogenized flow and transport equations are solved on the macroscopic scale, while effective parameters are…

偏微分方程分析 · 数学 2022-02-01 Stephan Gärttner , Peter Knabner , Nadja Ray

Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells…

流体动力学 · 物理学 2025-08-04 Maxx Yung

Homogenization method is used to analyse the equivalent behavior of transient flow of a passive solute through highly heterogeneous porous media. The flow is governed by a coupled system which includes an elliptic equation and a linear…

数学物理 · 物理学 2007-05-23 Brahim Amaziane , Alain Bourgeat , Mladen Jurak

Molecular dynamics simulation is applied to Poiseuille flow of liquid methane in planar graphite channels, covering channel diameters between 3 and 135 nm. On this length scale, a transition is found between the regime where local ordering…

In the last years, medical computer simulation has seen a great growth in several scientific branches, from modelling to numerical methods, going through computer science. The main goals of this incipient discipline are testing hypotheses…

流体动力学 · 物理学 2017-10-20 Cristóbal Rodero Gómez

Mathematical modelling of coupled flow systems containing a free-flow region in contact with a porous medium is challenging, especially for arbitrary flow directions to the fluid--porous interface. Transport processes in the free flow and…

流体动力学 · 物理学 2025-02-04 Linheng Ruan , Iryna Rybak

In this paper, a novel deep learning framework is proposed for temporal super-resolution simulation of blood vessel flows, in which a high-temporal-resolution time-varying blood vessel flow simulation is generated from a…

图像与视频处理 · 电气工程与系统科学 2021-11-23 Zhizheng Jiang , Fei Gao , Renshu Gu , Jinlan Xu , Gang Xu , Timon Rabczuk

Muscle contraction, both in skeletal and cardiac tissue, is driven by sarcomeres, the microscopic units inside muscle cells where thick myosin and thin actin filaments slide past each other. During contraction and relaxation, the…

流体动力学 · 物理学 2025-03-19 John Severn , Thomas Vacus , Eric Lauga

Predicting the flow of non-Newtonian fluids in porous structure is still a challenging issue due to the interplay betwen the microscopic disorder and the non-linear rheology. In this letter, we study the case of an yield stress fluid in a…

软凝聚态物质 · 物理学 2019-06-26 Chen Liu , Andrea De Luca , Alberto Rosso , Laurent Talon

A new slender-body theory for viscous flow, based on the concepts of dimensional reduction and hyperviscous regularization, is presented. The geometry of flat, elongated, or point-like rigid bodies immersed in a viscous fluid is…

流体动力学 · 物理学 2016-03-23 Giulio G. Giusteri , Eliot Fried