相关论文: Hybrid models for simulating blood flow in microva…
Cardiovascular networks span the body by branching across many generations of vessels. The resulting structure delivers blood over long distances to supply all cells with oxygen via the relatively short-range process of diffusion at the…
Various biological processes such as transport of oxygen and nutrients, thrombus formation, vascular angiogenesis and remodeling are related to cellular/subcellular level biological processes, where mesoscopic simulations resolving detailed…
Stable and accurate finite element methods are presented for Darcy flow in heterogeneous porous media with an interface of discontinuity of the hydraulic conductivity tensor. Accurate velocity fields are computed through global or local…
Blood flowing through microvascular bifurcations has been an active research topic for many decades, while the partitioning pattern of nanoscale solutes in the blood remains relatively unexplored. Here, we demonstrate a multiscale…
Boundary conditions at the interface between the free-flow region and the adjacent porous medium is a key issue for physically consistent modeling and accurate numerical simulation of flow and transport processes in coupled systems due to…
The correct choice of interface conditions and effective parameters for coupled macroscale free-flow and porous-medium models is crucial for a complete mathematical description of the problem under consideration and for accurate numerical…
This study proposes a new discrete neural operator for surrogate modeling of transient Darcy flow fields in heterogeneous porous media with random parameters. The new method integrates temporal encoding, operator learning and UNet to…
We perform direct numerical simulations (DNS) of a turbulent channel flow over porous walls. In the fluid region the flow is governed by the incompressible Navier--Stokes (NS) equations, while in the porous layers the Volume-Averaged…
We analyze the steady fluid flow in a porous medium containing a network of thin fissures i.e. width $\mathcal{O}(\epsilon)$, where all the cracks are generated by the rigid translation of a continuous piecewise $C^{1}$ functions in a fixed…
Reactive transport in permeable porous media is relevant for a variety of applications, but poses a significant challenge due to the range of length and time scales. Multiscale methods that aim to link microstructure with the macroscopic…
In this paper, we consider multipoint flux mixed finite element discretizations for slightly compressible Darcy flow in porous media. The methods are formulated on general meshes composed of triangles, quadrilaterals, tetrahedra or…
Internal haemorrhage, often leading to cardio-vascular arrest happens to be one of the prime sources of high fatality rates in mammals. We propose a simplistic model of fluid flow to specify the location of the haemorrhagic spots, which, if…
In this paper we present the two-level homogenization of the flow in a deformable double-porous structure described at two characteristic scales. The higher level porosity associated with the mesoscopic structure is constituted by channels…
In this paper, we combine deep learning concepts and some proper orthogonal decomposition (POD) model reduction methods for predicting flow in heterogeneous porous media. Nonlinear flow dynamics is studied, where the dynamics is regarded as…
Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…
Application of computation in many fields are growing fast in last two decades. Increasing on computation performance helps researchers to understand natural phenomena in many fields of science and technology including in life sciences.…
Motivated by the complex rheological behaviors observed in small/micro scale blood vessels, such as the Fahraeus effect, plasma-skimming, shear-thinning, etc., we develop a non-linear suspension model for blood. The viscosity is assumed to…
We generalize to three dimensions (3D) a recently developed improved multi-component pseudopotential lattice Boltzmann method and analyze its applicability to simulate flows through realistic porous media. The model is validated and…
MR vascular Fingerprinting proposes to use the MR Fingerprinting framework to quantitatively and simultaneously map several microvascular characteristics at a sub-voxel scale. The initial implementation assessed the local blood oxygenation…
Blood vessel networks in the brain play a crucial role in stroke research, where understanding their topology is essential for analyzing blood flow dynamics. However, extracting detailed topological vessel network information from…