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Tree structures appear in many fields of the life sciences, including phylogenetics, developmental biology and nucleic acid structures. Trees can be used to represent RNA secondary structures, which directly relate to the function of…

机器学习 · 计算机科学 2026-01-22 Pengyu Liu , Mariel Vázquez , Nataša Jonoska

In this experimental study we consider Steiner tree approximations that guarantee a constant approximation of ratio smaller than $2$. The considered greedy algorithms and approaches based on linear programming involve the incorporation of…

数据结构与算法 · 计算机科学 2015-12-10 Stephan Beyer , Markus Chimani

We compare the phylogenetic tensors for various trees and networks for two, three and four taxa. If the probability spaces between one tree or network and another are not identical then there will be phylogenetic tensors that could have…

种群与进化 · 定量生物学 2016-06-24 Jonathan Mitchell

Phylogenetic trees play a key role in the reconstruction of evolutionary relationships. Typically, they are derived from aligned sequence data (like DNA, RNA, or proteins) by using optimization criteria like, e.g., maximum parsimony (MP).…

种群与进化 · 定量生物学 2025-06-11 Mirko Wilde , Mareike Fischer

We study search trees with 2-way comparisons (2WCST's), which involve separate less-than and equal-to tests in their nodes, each test having two possible outcomes, yes and no. These trees have a much subtler structure than standard search…

数据结构与算法 · 计算机科学 2023-12-08 Sunny Atalig , Marek Chrobak

Reticulate events play an important role in determining evolutionary relationships. The problem of computing the minimum number of such events to explain discordance between two phylogenetic trees is a hard computational problem. Even for…

种群与进化 · 定量生物学 2014-05-02 Leo van Iersel , Steven Kelk , Nela Lekić , Celine Scornavacca

We study the natural problem of Triplet Reconstruction (also Rooted Triplets Consistency or Triplet Clustering), originally motivated in computational biology and relational databases (Aho, Sagiv, Szymanski, and Ullman, 1981): given $n$…

数据结构与算法 · 计算机科学 2023-04-06 Vaggos Chatziafratis , Konstantin Makarychev

Phylogenetic (evolutionary) trees and networks are leaf-labeled graphs that are widely used to represent the evolutionary relationships between entities such as species, languages, cancer cells, and viruses. To reconstruct and analyze…

数据结构与算法 · 计算机科学 2023-08-21 Michael J. Dinneen , Pankaj S. Ghodla , Simone Linz

Phylogenetic networks allow modeling reticulate evolution, capturing events such as hybridization and horizontal gene transfer. A fundamental computational problem in this context is the Tree Containment problem, which asks whether a given…

数据结构与算法 · 计算机科学 2026-03-13 Sebastian Bruchhold , Mathias Weller

We present the first sub-quadratic time algorithm that with high probability correctly reconstructs phylogenetic trees for short sequences generated by a Markov model of evolution. Due to rapid expansion in sequence databases, such very…

种群与进化 · 定量生物学 2012-06-01 Daniel G. Brown , Jakub Truszkowski

The subtree prune-and-regraft (SPR) distance metric is a fundamental way of comparing evolutionary trees. It has wide-ranging applications, such as to study lateral genetic transfer, viral recombination, and Markov chain Monte Carlo…

数据结构与算法 · 计算机科学 2017-11-07 Chris Whidden , Frederick A. Matsen

Vertex deletion and edge deletion problems play a central role in Parameterized Complexity. Examples include classical problems like Feedback Vertex Set, Odd Cycle Transversal, and Chordal Deletion. Interestingly, the study of edge…

数据结构与算法 · 计算机科学 2011-04-20 Pinar Heggernes , Pim van 't Hof , Benjamin Lévêque , Daniel Lokshtanov , Christophe Paul

We revisit the \textsc{$k$-Secluded Tree} problem. Given a vertex-weighted undirected graph $G$, its objective is to find a maximum-weight induced subtree $T$ whose open neighborhood has size at most $k$. We present a fixed-parameter…

数据结构与算法 · 计算机科学 2022-06-27 Huib Donkers , Bart M. P. Jansen , Jari J. H. de Kroon

Orchard and tree-child networks share an important property with phylogenetic trees: they can be completely reduced to a single node by iteratively deleting cherries and reticulated cherries. As it is the case with phylogenetic trees, the…

种群与进化 · 定量生物学 2024-03-22 Tomás M. Coronado , Joan Carles Pons , Gabriel Riera

Normal networks are an important class of phylogenetic networks that have compelling mathematical properties which align with intuition about inference from genetic data. While tools enabling widespread use of phylogenetic networks in the…

组合数学 · 数学 2025-12-16 Andrew Francis , Charles Semple

Kernelization is a theoretical formalization of efficient preprocessing for NP-hard problems. Empirically, preprocessing is highly successful in practice, for example in state-of-the-art ILP-solvers like CPLEX. Motivated by this, previous…

计算复杂性 · 计算机科学 2015-06-26 Bart M. P. Jansen , Stefan Kratsch

It is a classical result that any finite tree with positively weighted edges, and without vertices of degree 2, is uniquely determined by the weighted path distance between each pair of leaves. Moreover, it is possible for a (small) strict…

组合数学 · 数学 2012-09-12 Katharina T. Huber , Mike Steel

This paper tightens the best known analysis of Hein's 1989 algorithm to infer the topology of a weighted tree based on the lengths of paths between its leaves. It shows that the number of length queries required for a degree-$k$ tree of $n$…

数据结构与算法 · 计算机科学 2024-12-05 Jack Gardiner , Lachlan L. H. Andrew , Junhao Gan , Jean Honorio , Seeun William Umboh

In distance query reconstruction, we wish to reconstruct the edge set of a hidden graph by asking as few distance queries as possible to an oracle. Given two vertices $u$ and $v$, the oracle returns the shortest path distance between $u$…

数据结构与算法 · 计算机科学 2024-10-17 Paul Bastide , Carla Groenland

There exist several methods dealing with the reconstruction of rooted phylogenetic networks explaining different evolutionary histories given by rooted binary phylogenetic trees. In practice, however, due to insufficient information of the…

种群与进化 · 定量生物学 2015-12-18 Benjamin Albrecht