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The binding of a ligand molecule to a protein is often accompanied by conformational changes of the protein. A central question is whether the ligand induces the conformational change (induced-fit), or rather selects and stabilizes a…

生物大分子 · 定量生物学 2008-09-04 Thomas R. Weikl , Carola von Deuster

We show that quasi-alternating links arise naturally when considering surgery on a strongly invertible L-space knot (that is, a knot that yields an L-space for some Dehn surgery). In particular, we show that for many known classes of…

几何拓扑 · 数学 2009-10-05 Liam Watson

Using a lattice model of polymers in a tube, we define one way to characterise different configurations of a given knot as either "local" or "non-local" and, for several ring polymer models, we provide both theoretical and numerical…

This paper investigates the relationship between the signature and the crossing number of knots and links. We refine existing theorems and provide a comprehensive classification of links with specific properties, particularly those with…

几何拓扑 · 数学 2024-10-02 Kai Ishihara , Kei Okada , Koya Shimokawa

Given any unoriented link diagram, a group of new knot invariants are constructed. Each of them satisfies a generalized 4 term skein relation. The coefficients of each invariant is from a commutative ring. Homomorphisms and representations…

几何拓扑 · 数学 2010-04-14 Zhiqing Yang , Jifu Xiao

We elaborate that general intersecting brane models on orbifolds are obtained from type I string compactifications and their T-duals. Symmetry breaking and restoration occur via recombination and parallel separation of branes, preserving…

高能物理 - 理论 · 物理学 2008-11-26 Kang-Sin Choi

A quasi-coherent ringed scheme is a pair (X,A), where X is a scheme, and A is a noncommutative quasi-coherent O_X-ring. We introduce dualizing complexes over quasi-coherent ringed schemes and study their properties. For a separated…

代数几何 · 数学 2007-05-23 Amnon Yekutieli , James J. Zhang

Tied links and the tied braid monoid were introduced recently by the authors and used to define new invariants for classical links. Here, we give a version purely algebraic-combinatoric of tied links. With this new version we prove that the…

几何拓扑 · 数学 2021-01-28 Francesca Aicardi , Jesus Juyumaya

Motivated by the study of reversal behaviour of myxobacteria, in this article we are interested in a kinetic model for reversal dynamics, in which particles with directions close to be opposite undergo binary collision resulting in…

偏微分方程分析 · 数学 2023-05-22 Amic Frouvelle , Laura Kanzler , Christian Schmeiser

Accurate image segmentation plays a crucial role in medical image analysis, yet it faces great challenges of various shapes, diverse sizes, and blurry boundaries. To address these difficulties, square kernel-based encoder-decoder…

图像与视频处理 · 电气工程与系统科学 2022-01-02 Qian Yu , Lei Qi , Luping Zhou , Lei Wang , Yilong Yin , Yinghuan Shi , Wuzhang Wang , Yang Gao

Petri nets are a mathematical language for modeling and reasoning about distributed systems. In this paper we propose an approach to Petri nets for embedding reversibility, i.e., the ability of reversing an executed sequence of operations…

计算机科学中的逻辑 · 计算机科学 2020-10-09 Anna Philippou , Kyriaki Psara

The knot concordance group can be contextualized as organizing problems about 3- and 4-dimensional spaces and the relationships between them. Every 3-manifold is surgery on some link, not necessarily a knot, and thus it is natural to ask…

几何拓扑 · 数学 2023-08-30 Miriam Kuzbary

Quantized response is one distinguishing feature of a topological system. In non-Hermitian systems, the spectral winding topology yields quantized steady-state response. By considering two weakly coupled non-Hermitian chains, we discover…

介观与纳米尺度物理 · 物理学 2022-06-10 Hui-Qiang Liang , Sen Mu , Jiangbin Gong , Linhu Li

Accurate prediction of protein-ligand binding affinity is crucial for rapid and efficient drug development. Recently, the importance of predicting binding affinity has led to increased attention on research that models the three-dimensional…

机器学习 · 计算机科学 2024-07-17 Seungyeon Choi , Sangmin Seo , Sanghyun Park

The bias-reversal symmetry -- where reversing an external bias inverts the current without changing its magnitude -- is a hallmark of nonequilibrium transport. While this property holds in homogeneous systems such as the asymmetric simple…

统计力学 · 物理学 2026-04-20 Issei Sakai , Takuma Akimoto

Knot theory provides a powerful tool for the understanding of topological matters in biology, chemistry, and physics. Here knot theory is introduced to describe topological phases in the quantum spin system. Exactly solvable models with…

强关联电子 · 物理学 2019-06-24 X. M. Yang , L. Jin , Z. Song

In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting…

种群与进化 · 定量生物学 2014-03-25 Richard A. Neher , Taylor A. Kessinger , Boris I. Shraiman

This article introduces a natural extension of colouring numbers of knots, called colouring polynomials, and studies their relationship to Yang-Baxter invariants and quandle 2-cocycle invariants. For a knot K in the 3-sphere let \pi_K be…

几何拓扑 · 数学 2007-11-20 Michael Eisermann

There are a number of clinically relevant tasks in digital breast tomosynthesis (DBT) involving the detection and visual assessment of fiber-like structures such as Cooper's ligaments, blood vessels, and spiculated lesions. Such structures…

医学物理 · 物理学 2018-03-14 Sean D. Rose , Ingrid Reiser , Emil Y. Sidky , Xiaochuan Pan

Knotted proteins, when forced through the pores, can get stuck if the knots in their backbone tighten under force. Alternatively, the knot can slide off the chain, making translocation possible. We construct a simple energy landscape model…

统计力学 · 物理学 2023-11-08 Karol Capała , Piotr Szymczak