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To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

种群与进化 · 定量生物学 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

This research presents an advanced fractional-order compartmental model designed to delve into the complexities of COVID-19 transmission dynamics, specifically accounting for the influence of environmental pathogens on disease spread. By…

种群与进化 · 定量生物学 2024-07-09 Moein Khalighi , Faïçal Ndaïrou , Leo Lahti

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

动力系统 · 数学 2025-10-03 Abdallah Alsammani

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

细胞行为 · 定量生物学 2018-08-16 Enrico Gavagnin , Christian A. Yates

Stochastic ordering among distributions has been considered in a variety of scenarios. Economic studies often involve research about the ordering of investment strategies or social welfare. However, as noted in the literature, stochastic…

Among various possible causes of autoimmune disease, an important role is played by infections that can result in a breakdown of immune tolerance, primarily through the mechanism of "molecular mimicry". In this paper we propose and analyse…

组织与器官 · 定量生物学 2018-05-21 F. Fatehi , S. N. Kyrychko , A. Ross , Y. N. Kyrychko , K. B. Blyuss

Infectious disease spread is a multi-scale process composed of within-host (biological) and between-host (social) drivers and disentangling them from each other is a central challenge in epidemiology. Here, we introduce VIBES, a multi-scale…

Agent based models (ABMs) are a useful tool for modeling spatio-temporal population dynamics, where many details can be included in the model description. Their computational cost though is very high and for stochastic ABMs a lot of…

Determinants of COVID-19 clinical severity are commonly assessed by transverse or longitudinal studies of the fatality counts. However, the fatality counts depend both on disease clinical severity and transmissibility, as more infected also…

种群与进化 · 定量生物学 2021-09-02 Sofija Markovic , Andjela Rodic , Igor Salom , Ognjen Milicevic , Magdalena Djordjevic , Marko Djordjevic

Breaking a complex bio-social phenomenon (epidemic) into its components, considering the processes that determine its dynamics, formalizing the accepted hypotheses in mathematical equations, selecting appropriate experimental and…

物理与社会 · 物理学 2020-06-16 A. V. Sokolov , L. A. Sokolova

The aim of the paper is to describe two models of Covid-19 infection dynamics. For this purpose a special class of branching processes with two types of individuals is considered. These models are intended to use only the observed daily…

种群与进化 · 定量生物学 2020-05-05 Nikolay M. Yanev , Vessela K. Stoimenova , Dimitar V. Atanasov

The Banana Bunchy Top Virus (BBTV) is one of the most economically important vector-borne banana diseases throughout the Asia-Pacific Basin and presents a significant challenge to the agricultural sector. Current models of BBTV are largely…

应用统计 · 统计学 2020-07-01 Abhishek Varghese , Christopher Drovandi , Kerrie Mengersen , Antonietta Mira

Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet…

Infectious diseases that incorporate pre-symptomatic transmission are challenging to monitor, model, predict and contain. We address this scenario by studying a variant of a stochastic susceptible-exposed-infected-recovered model on…

物理与社会 · 物理学 2021-05-07 Bo Li , David Saad

Nowadays, Vector-Borne Diseases (VBDs) raise a severe threat for public health, accounting for a considerable amount of human illnesses. Recently, several surveillance plans have been put in place for limiting the spread of such diseases,…

We analyze four models of epidemic spreading using a stochastic approach in which the primary stochastic variables are the numbers of individuals in each class. The stochastic approach is described by a master equation and the transition…

统计力学 · 物理学 2020-10-28 Tânia Tomé , Mário J. de Oliveira

Epidemics are often modelled using non-linear dynamical systems observed through partial and noisy data. In this paper, we consider stochastic extensions in order to capture unknown influences (changing behaviors, public interventions,…

应用统计 · 统计学 2012-11-06 Joseph Dureau , Konstantinos Kalogeropoulos , Marc Baguelin

The dynamics of contact networks and epidemics of infectious diseases often occur on comparable time scales. Ignoring one of these time scales may provide an incomplete understanding of the population dynamics of the infection process. We…

种群与进化 · 定量生物学 2021-02-09 Luis E C Rocha , Naoki Masuda

The importation and subsequent establishment of novel pathogenic strains in a population is subject to a large degree of uncertainty due to the stochastic nature of the disease dynamics. Mathematical models need to take this stochasticity…

种群与进化 · 定量生物学 2024-12-02 Jacob Curran-Sebastian , Frederik Mølkjær Andersen , Samir Bhatt

The breeding method is a computationally cheap way to generate flow-adapted ensembles to be used in probabilistic forecasts. Its main disadvantage is that the ensemble may lack diversity and collapse to a low-dimensional subspace. To still…

大气与海洋物理 · 物理学 2019-05-01 Brent Giggins , Georg A. Gottwald