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Deterministic approximations to stochastic Susceptible-Infectious-Susceptible models typically predict a stable endemic steady-state when above threshold. This can be hard to relate to the underlying stochastic dynamics, which has no…

种群与进化 · 定量生物学 2022-08-12 Christopher E. Overton , Robert R. Wilkinson , Adedapo Loyinmi , Joel C. Miller , Kieran J. Sharkey

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

概率论 · 数学 2011-01-21 Sylvie Méléard , Sylvie Roelly

Global strategies to contain a pandemic, such as social distancing and protective measures, are designed to reduce the overall transmission rate between individuals. Despite such measures, essential institutions, including hospitals,…

种群与进化 · 定量生物学 2022-09-07 Roberto Morán-Tovar , Henning Gruell , Florian Klein , Michael Lässig

Predicting the spread of vector-borne diseases in response to incursions requires knowledge of both host and vector demographics in advance of an outbreak. Whereas host population data is typically available, for novel disease introductions…

种群与进化 · 定量生物学 2015-06-02 Chris Jewell , Richard Brown

We propose a robust parameter estimation method for dynamical systems based on Statistical Learning techniques which aims to estimate a set of parameters that well fit the dynamics in order to obtain robust evidences about the qualitative…

统计方法学 · 统计学 2021-02-26 Diego Marcondes

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

物理与社会 · 物理学 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

种群与进化 · 定量生物学 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

The interplay of seasonality, the system's nonlinearities and intrinsic stochasticity is studied for a seasonally forced susceptible-exposed-infective-recovered stochastic model. The model is explored in the parameter region that…

生物物理 · 物理学 2010-10-19 Ganna Rozhnova , Ana Nunes

An individual-based model of the infectious disease spread among the urban population is considered. A system of stochastic equations, which describes changes in quantities of four population groups, susceptible, exposed, infected…

种群与进化 · 定量生物学 2011-11-11 Vasiliy Leonenko

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…

统计计算 · 统计学 2017-02-14 Jonathan Fintzi , Xiang Cui , Jon Wakefield , Vladimir N. Minin

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

统计方法学 · 统计学 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

种群与进化 · 定量生物学 2026-05-13 Seong Jun Park

At the onset of the Covid-19 pandemic, a number of non-pharmaceutical interventions have been implemented in order to reduce transmission, thus leading to multiple phases of transmission. The disease reproduction number $R_t$, a way of…

应用统计 · 统计学 2023-05-03 Petros Barmpounakis , Nikolaos Demiris

Viruses constantly undergo mutations with genomic changes. The propagation of variants of viruses is an interesting problem. We perform numerical simulations of the microscopic epidemic model based on network theory for the spread of…

种群与进化 · 定量生物学 2025-01-14 Yutaka Okabe , Akira Shudo

We propose and analyze an epidemiological model for vector borne diseases that integrates a multi-stage vector population and several host sub-populations which may be characterized by a variety of compartmental model types: subpopulations…

种群与进化 · 定量生物学 2023-06-28 Francis G. T. Kamba , Leonard C. Eze , Jean Claude Kamgang , Christopher P. Thron

Effective utilization of flexible loads for grid services, while satisfying end-user preferences and constraints, requires an accurate estimation of the aggregated predictive flexibility offered by the electrical loads. Virtual battery (VB)…

系统与控制 · 电气工程与系统科学 2020-03-20 Indrasis Chakraborty , Sai Pushpak Nandanoori , Soumya Kundu , Karanjit Kalsi

We propose a deterministic SAIVRD model and a stochastic SARV model of the epidemic COVID-19 involving asymptomatic infections and vaccinations to conduct data forecasts using time-dependent parameters. The forecast by our deterministic…

种群与进化 · 定量生物学 2022-09-28 Bo-Sheng Chen , Zong-Ying Wu , Yen-Jia Chen , Jann-Long Chern

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Human migration exhibits complex spatiotemporal dependence driven by environmental and socioeconomic forces. Modeling such patterns at scale requires methods that accommodate many random effects while remaining feasible when raw data or…

统计方法学 · 统计学 2026-05-29 Lida Chalangar Jalili Dehkharghani , Li-Hsiang Lin