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We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

种群与进化 · 定量生物学 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual

Different countries -- and sometimes different regions within the same countries -- have adopted different strategies in trying to contain the ongoing COVID-19 epidemic; these mix in variable parts social confinement, early detection and…

种群与进化 · 定量生物学 2020-07-17 Giuseppe Gaeta

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

种群与进化 · 定量生物学 2020-05-04 Andrew Lesniewski

As offered by the World Health Organisation (WHO), close to half of the population in the world's resides in dengue-risk zones. Dengue viruses are transmitted to individuals by Aedes mosquito species infected bite (Ae. Albopictus of Ae.…

种群与进化 · 定量生物学 2025-03-12 Burcu Gürbüz , Aytül Gökçe , Segun I. Oke , Michael O. Adeniyi , Mayowa M. Ojo

Time delay in general leads to instability in some systems, while a specific feedback with delay can control fluctuated motion in nonlinear deterministic systems to a stable state. In this paper, we consider a non-stationary stochastic…

混沌动力学 · 物理学 2017-08-02 Hiroyasu Ando , Kohta Takehara , Miki U. Kobayashi

Traditional biomedical approaches treat diseases in isolation, but the importance of synergistic disease interactions is now recognized. As a first step we present and analyze a simple coinfection model for two diseases affecting…

动力系统 · 数学 2015-04-21 Marcos Marvá , Ezio Venturino , Rafael Bravo de la Parra

Cities have long served as nucleating centers for human development and advancement. Cities have facilitated the spread of both human creativity and human disease, and at the same time, efforts to minimize the spread of disease have…

物理与社会 · 物理学 2020-11-10 Harold M Hastings , Tai Young-Taft

When an unprecedented infectious disease with high mortality and transmissibility emerges, immediate usage of vaccines or medicines is hardly available. Thus, many health authorities rely on non-pharmaceutical interventions through…

物理与社会 · 物理学 2022-01-21 Minsuk Kim , Soon-Hyung Yook

In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…

偏微分方程分析 · 数学 2025-02-11 Marcelo Bongarti , Christian Parkinson , Weinan Wang

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

We introduce a general system of ordinary differential equations that includes some classical and recent models for the epidemic spread in a closed population without vital dynamic in a finite time horizon. The model is vectorial, in the…

最优化与控制 · 数学 2023-06-21 Lorenzo Freddi

Pandemics involve the high transmission of a disease that impacts global and local health and economic patterns. The impact of a pandemic can be minimized by enforcing certain restrictions on a community. However, while minimizing infection…

人工智能 · 计算机科学 2024-02-13 Ishir Rao

We formulate an age-structured nonlinear partial differential equation model that features short-term immigration effects in a population. Individuals can immigrate into the population as any of the three stages in the model: susceptible,…

种群与进化 · 定量生物学 2019-08-07 Fabio Sanchez , Juan Gabriel Calvo

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

种群与进化 · 定量生物学 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

The SIR pandemic model suffers from an unrealistic assumption: The rate of removal from the infectious class of individuals is assumed to be proportional to the number of infectious individuals. This means that a change in the rate of…

种群与进化 · 定量生物学 2021-02-23 Paul A. Reiser

We propose a mathematical spatiotemporal epidemic SICA model with a control strategy. The spatial behavior is modeled by adding a diffusion term with the Laplace operator, which is justified and interpreted both mathematically and…

最优化与控制 · 数学 2022-07-12 Houssine Zine , Abderrahim El Adraoui , Delfim F. M. Torres

Over the past several decades there has been a proliferation of epidemiological models with ordinary derivatives replaced by fractional derivatives in an an-hoc manner. These models may be mathematically interesting but their relevance is…

种群与进化 · 定量生物学 2016-03-31 C. N. Angstmann , B. I. Henry , A. V. McGann

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

种群与进化 · 定量生物学 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

We study a dynamic infection spread model, inspired by the discrete time SIR model, where infections are spread via non-isolated infected individuals. While infection keeps spreading over time, a limited capacity testing is performed at…

统计方法学 · 统计学 2022-01-25 Batuhan Arasli , Sennur Ulukus

The COVID-19 pandemic has led to significant changes in how people are currently living their lives. To determine how to best reduce the effects of the pandemic and start reopening societies, governments have drawn insights from…

其他定量生物学 · 定量生物学 2020-09-08 Heather Z. Brooks , Unchitta Kanjanasaratool , Yacoub H. Kureh , Mason A. Porter