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In meta-analysis of diagnostic test accuracy, summary receiver operating characteristic (SROC) is a recommended method to summarize the discriminant capacity of a diagnostic test in the presence of study-specific cutoff values and the area…

统计方法学 · 统计学 2023-01-10 Yi Zhou , Ao Huang , Satoshi Hattori

The receiver operating characteristic (ROC) curve is a powerful statistical tool and has been widely applied in medical research. In the ROC curve estimation, a commonly used assumption is that larger the biomarker value, greater severity…

统计方法学 · 统计学 2023-02-24 Dingding Hu , Meng Yuan , Tao Yu , Pengfei Li

The summary receiver operating characteristic (SROC) curve has been recommended as one important meta-analytical summary to represent the accuracy of a diagnostic test in the presence of heterogeneous cutoff values. However, selective…

统计方法学 · 统计学 2024-01-11 Yi Zhou , Ao Huang , Satoshi Hattori

Receiver operating characteristic (ROC) analysis is one of the most popular approaches for evaluating and comparing the accuracy of medical diagnostic tests. Although various methodologies have been developed for estimating ROC curves and…

统计方法学 · 统计学 2022-08-16 Ainesh Sewak , Torsten Hothorn

The empirical likelihood is a powerful nonparametric tool, that emulates its parametric counterpart -- the parametric likelihood -- preserving many of its large-sample properties. This article tackles the problem of assessing the…

统计方法学 · 统计学 2023-05-29 Duc-Khanh To , Gianfranco Adimari , Monica Chiogna

In diagnostic studies, researchers frequently encounter imperfect reference standards with some misclassified labels. Treating these as gold standards can bias receiver operating characteristic (ROC) curve analysis. To address this issue,…

统计方法学 · 统计学 2025-02-13 Yifan Sun , Peijun Sang , Qinglong Tian , Pengfei Li

In medical diagnostics, leveraging multiple biomarkers can significantly improve classification accuracy compared to using a single biomarker. While existing methods based on exponential tilting or density ratio models have shown promise,…

统计方法学 · 统计学 2026-01-08 Fangyong Zheng , Pengfei Li , Tao Yu

Likelihood-free methods are useful for parameter estimation of complex models with intractable likelihood functions for which it is easy to simulate data. Such models are prevalent in many disciplines including genetics, biology, ecology…

统计方法学 · 统计学 2022-03-29 Christopher Drovandi , David T Frazier

Free-response observer performance studies are of great importance for accuracy evaluation and comparison in tasks related to the detection and localization of multiple targets or signals. The free-response receiver operating characteristic…

统计方法学 · 统计学 2025-12-25 Jiarui Sun , Kaiyuan Liu , Xiao-Hua Zhou

Estimating average human performance has been performed inconsistently in research in diagnostic medicine. This has been particularly apparent in the field of medical artificial intelligence, where humans are often compared against AI…

统计方法学 · 统计学 2020-09-28 Luke Oakden-Rayner , Lyle Palmer

Conventional likelihood-based information criteria for model selection rely on the distribution assumption of data. However, for complex data that are increasingly available in many scientific fields, the specification of their underlying…

统计方法学 · 统计学 2020-06-25 Chixiang Chen , Ming Wang , Rongling Wu , Runze Li

In the analysis of prognosis studies with time-to-event outcomes, dichotomization of patients is often made. As the evaluations of prognostic capacity, the survivals of groups with high/low expression of the biomarker are often estimated by…

统计方法学 · 统计学 2023-06-01 Yi Zhou , Ao Huang , Satoshi Hattori

Many scientifically well-motivated statistical models in natural, engineering and environmental sciences are specified through a generative process, but in some cases it may not be possible to write down a likelihood for these models…

统计计算 · 统计学 2018-10-10 Sanjay Chaudhuri , Subhro Ghosh , David J. Nott , Kim Cuc Pham

The area under a receiver operating characteristic curve (AUC) is a useful tool to assess the performance of continuous-scale diagnostic tests on binary classification. In this article, we propose an empirical likelihood (EL) method to…

统计方法学 · 统计学 2022-05-05 Chul Moon , Xinlei Wang , Johan Lim

The Receiver Operating Characteristic (ROC) curve is a useful tool that measures the discriminating power of a continuous variable or the accuracy of a pharmaceutical or medical test to distinguish between two conditions or classes. In…

统计方法学 · 统计学 2022-07-26 Ana M. Bianco , Graciela Boente , Wenceslao Gonzalez-Manteiga

Bayesian inference and the use of posterior or posterior predictive probabilities for decision making have become increasingly popular in clinical trials. The current practice in Bayesian clinical trials relies on a hybrid…

统计方法学 · 统计学 2024-04-30 Shirin Golchi , James Willard

We provide a comprehensive theory of conducting in-sample statistical inference about receiver operating characteristic (ROC) curves that are based on predicted values from a first stage model with estimated parameters (such as a logit…

计量经济学 · 经济学 2021-12-06 Yu-Chin Hsu , Robert P. Lieli

Logistic regression models are a popular and effective method to predict the probability of categorical response data. However inference for these models can become computationally prohibitive for large datasets. Here we adapt ideas from…

统计方法学 · 统计学 2020-08-25 Tom Whitaker , Boris Beranger , Scott A. Sisson

Meta analysis is commonly-used to synthesize multiple results from individual studies. However, its validation is usually threatened by publication bias and between-study heterogeneity, which can be captured by the Copas selection model.…

统计方法学 · 统计学 2025-07-21 Mengke Li , Yukun Liu , Pengfei Li , Jing Qin

We consider the problem of parametric statistical inference when likelihood computations are prohibitively expensive but sampling from the model is possible. Several so-called likelihood-free methods have been developed to perform inference…

机器学习 · 统计学 2020-09-14 Owen Thomas , Ritabrata Dutta , Jukka Corander , Samuel Kaski , Michael U. Gutmann
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