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Alternating recurrent events, where subjects experience two potentially correlated event types over time, are common in healthcare, social, and behavioral studies. Often there is a primary event of interest that, when triggered, initiates a…

统计方法学 · 统计学 2025-10-29 Abigail Loe , Susan Murray , Zhenke Wu

In survival analysis it often happens that some subjects under study do not experience the event of interest; they are considered to be `cured'. The population is thus a mixture of two subpopulations: the one of cured subjects, and the one…

统计理论 · 数学 2017-01-16 Valentin Patilea , Ingrid Van Keilegom

Adaptive experimentation enables efficient estimation of causal effects, but existing methods are not designed for survival data with censoring, where event times are only partially observed (e.g., overall survival in cancer trials but with…

机器学习 · 计算机科学 2026-05-19 Yuxin Wang , Dennis Frauen , Jonas Schweisthal , Maresa Schröder , Emil Javurek , Stefan Feuerriegel

In a typical Event-Based Surveillance setting, a stream of web documents is continuously monitored for disease reporting. A structured representation of the disease reporting events is extracted from the raw text, and the events are then…

计算机与社会 · 计算机科学 2011-01-05 Avaré Stewar , Ricardo Lage , Ernesto Diaz-Aviles , Peter Dolog

A very classical problem in statistics is to test the stochastic superiority of one distribution to another. However, many existing approaches are developed for independent samples and, moreover, do not take censored data into account. We…

统计方法学 · 统计学 2023-06-19 Dennis Dobler , Kathrin Möllenhoff

The Mann-Whitney effect is an intuitive measure for discriminating two survival distributions. Here we analyze various inference techniques for this parameter in a two-sample survival setting with independent right-censoring, where the…

统计理论 · 数学 2016-09-26 Dennis Dobler , Markus Pauly

Interval-censored data analysis is important in biomedical statistics for any type of time-to-event response where the time of response is not known exactly, but rather only known to occur between two assessment times. Many clinical trials…

统计方法学 · 统计学 2019-06-12 Weichi Yao , Halina Frydman , Jeffrey S. Simonoff

When data are collected subject to a detection limit, observations below the detection limit may be considered censored. In addition, the domain of such observations may be restricted; for example, values may be required to be non-negative.…

应用统计 · 统计学 2020-06-30 Justin R. Williams , Hyung-Woo Kim , Catherine M. Crespi

We propose a censored quantile regression estimator motivated by unbiased estimating equations. Under the usual conditional independence assumption of the survival time and the censoring time given the covariates, we show that the proposed…

统计理论 · 数学 2013-02-04 Chenlei Leng , Xingwei Tong

Screening and surveillance are routinely used in medicine for early detection of disease and close monitoring of progression. Biomarkers are one of the primarily tools used for these tasks, but their successful translation to clinical…

Risk prediction models are widely used to guide real-world decision-making in areas such as healthcare and economics, and they also play a key role in estimating nuisance parameters in semiparametric inference. The super learner is a…

统计方法学 · 统计学 2025-09-05 Anders Munch , Thomas A. Gerds

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

机器学习 · 统计学 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

This paper studies a service system in which arriving customers are provided with information about the delay they will experience. Based on this information they decide to wait for service or to leave the system. Specifically, every…

概率论 · 数学 2022-08-31 Yoshiaki Inoue , Liron Ravner , Michel Mandjes

Left censoring can occur with relative frequency when analysing recurrent events in epidemiological studies, especially observational ones. Concretely, the inclusion of individuals that were already at risk before the effective initiation…

统计方法学 · 统计学 2021-02-24 Gilma Hernández-Herrera , David Moriña , Albert Navarro

This paper presents a conformal prediction procedure to generate two-sided or one-sided prediction intervals for survival times in the presence of right censoring. Specifically, the method provides two-sided predictive bounds for…

统计方法学 · 统计学 2025-06-23 Chris Holmes , Ariane Marandon

The study of survival data often requires taking proper care of the censoring mechanism that prohibits complete observation of the data. Under right censoring, only the first occurring event is observed: either the event of interest, or a…

统计理论 · 数学 2025-03-25 Myrthe D'Haen , Ingrid Van Keilegom , Anneleen Verhasselt

In observational studies of survival time featuring a binary time-dependent treatment, the hazard ratio (an instantaneous measure) is often used to represent the treatment effect. However, investigators are often more interested in the…

统计方法学 · 统计学 2020-05-21 Yun Li , Douglas E. Schaubel , Kevin He

This report is designed to clarify a few points about the article "Semiparametric modeling of grouped current duration data with preferential reporting" by McLain, Sundaram, Thoma and Louis in Statistics in Medicine (McLain et al., 2014,…

应用统计 · 统计学 2018-01-03 Alexander C. McLain , Rajeshwari Sundaram , Marie Thoma , Germaine M. Buck Louis

Methods for the evaluation of the predictive accuracy of biomarkers with respect to survival outcomes subject to right censoring have been discussed extensively in the literature. In cancer and other diseases, survival outcomes are commonly…

统计方法学 · 统计学 2018-06-06 Yuan Wu , Xiaofei Wang , Jiaxing Lin , Beilin Jia , Kouros Owzar

Nonparametric and semiparametric methods are commonly used in survival analysis to mitigate the bias due to model misspecification. However, such methods often cannot estimate upper-tail survival quantiles when a sizable proportion of the…

统计方法学 · 统计学 2019-07-19 Yifan Wang , Tian You , Martin Lysy