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相关论文: Geometric stability considerations of the ribosome…

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The ribosome flow model (RFM) is a phenomenological model for the unidirectional flow of particles along a 1D chain of $n$ sites. The RFM has been extensively used to study the dynamics of ribosome flow along a single mRNA molecule during…

分子网络 · 定量生物学 2026-01-09 Aliza Ehrman , Thomas Kriecherbauer , Lars Gruene , Michael Margaliot

In this work we propose a novel method to ensure important entropy inequalities are satisfied semi-discretely when constructing reduced order models (ROMs) on nonlinear reduced manifolds. We are in particular interested in ROMs of systems…

数值分析 · 数学 2024-07-18 Robin Klein , Benjamin Sanderse , Pedro Costa , Rene Pecnik , Ruud Henkes

The Ribosome Flow Model (RFM) describes the unidirectional movement of interacting particles along a one-dimensional chain of sites. As a site becomes fuller, the effective entry rate into this site decreases. The RFM has been used to model…

网络与互联网体系结构 · 计算机科学 2015-08-26 Yoram Zarai , Oz Mendel , Michael Margaliot

By identifying Hamiltonian flows with geodesic flows of suitably chosen Riemannian manifolds, it is possible to explain the origin of chaos in classical Newtonian dynamics and to quantify its strength. There are several possibilities to…

统计力学 · 物理学 2020-01-29 Loris Di Cairano , Matteo Gori , Marco Pettini

The ribosome flow model with input and output (RFMIO) is a deterministic dynamical system that has been used to study the flow of ribosomes during mRNA translation. The RFMIO and its variants encapsulate important properties that are…

分子网络 · 定量生物学 2018-11-20 Itzik Nanikashvili , Yoram Zarai , Alexander Ovseevich , Tamir Tuller , Michael Margaliot

A recently proposed renormalization group technique, based on the hierarchical structures present in theories with fluctuating geometry, is implemented in the model of branched polymers. The renormalization group equations can be solved…

高能物理 - 格点 · 物理学 2009-10-28 Jan Ambjorn , Piotr Bialas , Jerzy Jurkiewicz

We study holographic RG flows in a 3d supergravity model from the side of the dynamical system theory. The gravity equations of motion are reduced to an autonomous dynamical system. Then we find equilibrium points of the system and analyze…

高能物理 - 理论 · 物理学 2023-03-21 Anastasia A. Golubtsova , Marina K. Usova

In this paper the qualitative dynamical properties of so-called generalized ribosome flow models are studied. Ribosome flow models known from the literature are generalized by allowing an arbitrary directed network structure between the…

动力系统 · 数学 2023-07-19 G. Szederkenyi , M. A. Vaghy

This paper is concerned with the global dynamics of a hybrid parabolic-hyperbolic model describing populations with distinct dispersal and sedentary stages. We first establish the global well-posedness of solutions, prove a comparison…

偏微分方程分析 · 数学 2025-09-16 Qihua Huang , Minglong Wang , Yixiang Wu

In this paper we analyze the stability of equilibrium manifolds of hyperbolic shallow water moment equations. Shallow water moment equations describe shallow flows for complex velocity profiles which vary in vertical direction and the…

流体动力学 · 物理学 2020-11-18 Qian Huang , Julian Koellermeier , Wen-An Yong

The ribosome flow model (RFM) is a phenomenological model for the flow of particles along a 1D chain of $n$ sites. It has been extensively used to study ribosome flow along the mRNA molecule during translation. When the transition rates…

最优化与控制 · 数学 2025-05-20 Ron Ofir , Thomas Kriecherbauer , Lars Grüne , Michael Margaliot

In this paper we introduce and study a new kind of hyperbolic geometric flows --dissipative hyperbolic geometric flow. This kind of flow is defined by a system of quasilinear wave equations with dissipative terms. Some interesting exact…

微分几何 · 数学 2007-09-18 Wen-Rong Dai , De-Xing Kong , Kefeng Liu

We consider four extended Ricci flow systems---that is, Ricci flow coupled with other geometric flows---and prove dynamical stability of certain classes of stationary solutions of these flows. The systems include Ricci flow coupled with…

微分几何 · 数学 2015-06-22 Michael Bradford Williams

We present a novel geometric approach for determining the unique structure of a Hamiltonian and establishing an instability criterion for quantum quadratic systems. Our geometric criterion provides insights into the underlying geometric…

量子物理 · 物理学 2023-05-31 Xuanloc Leu , Xuan-Hoai Thi Nguyen , Jinhyoung Lee

The rimming flow of a viscoelastic thin film inside a rotating horizontal cylinder is studied theoretically. Attention is given to the onset of non-Newtonian free-surface instability in creeping flow. This non-inertial instability has been…

流体动力学 · 物理学 2015-09-18 Sergei Fomin , Ravi Shankar , Peter Haine

The ribosomal density along the coding region of the mRNA molecule affect various fundamental intracellular phenomena including: protein production rates, organismal fitness, ribosomal drop off, and co-translational protein folding. Thus,…

基因组学 · 定量生物学 2017-05-19 Yoram Zarai , Michael Margaliot , Eduardo D. Sontag , Tamir Tuller

A novel reduced-order model (ROM) formulation for incompressible flows is presented with the key property that it exhibits non-linearly stability, independent of the mesh (of the full order model), the time step, the viscosity, and the…

数值分析 · 数学 2020-08-12 B. Sanderse

This paper explores the evolution and monotonicity of geometric constants within the framework of extended Ricci flows, incorporating variable coupling parameters. Building on Hamiltons foundational Ricci flow and subsequent extensions by…

微分几何 · 数学 2024-12-10 Shouvik Datta Choudhury

Complex systems with many degrees of freedom are typically intractable, but some of their behaviors may admit simpler effective descriptions. The question of when such effective descriptions are possible remains open. The paradigmatic…

统计力学 · 物理学 2020-11-26 Charlotte Strandkvist , Pavel Chvykov , Mikhail Tikhonov

We design strategies in nonlinear geometric analysis to temper the effects of adversarial learning for sufficiently smooth data of numerical method-type dynamics in encoder-decoder methods, variational and deterministic, through the use of…

数值分析 · 数学 2026-05-29 Andrew Gracyk
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