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In wet-lab experiments, the slime mold Physarum polycephalum has demonstrated its ability to solve shortest path problems and to design efficient networks. For the shortest path problem, a mathematical model for the evolution of the slime…

In the realm of biological flow networks, the ability to dynamically adjust to varying demands is paramount. Drawing inspiration from the remarkable adaptability of Physarum polycephalum, we present a novel physical mechanism tailored to…

软凝聚态物质 · 物理学 2023-10-05 Vidyesh Rao Anisetti , Ananth Kandala , J. M. Schwarz

Physarum Polycephalum is a slime mold that is apparently able to solve shortest path problems. A mathematical model has been proposed by biologists to describe the feedback mechanism used by the slime mold to adapt its tubular channels…

数据结构与算法 · 计算机科学 2019-07-01 Vincenzo Bonifaci , Kurt Mehlhorn , Girish Varma

Optimization of fluid transport in the slime mold Physarum polycephalum has been the subject of several modeling efforts in recent literature. Existing models assume that the tube adaptation mechanism in P. polycephalum's tubular network is…

组织与器官 · 定量生物学 2019-07-01 Vincenzo Bonifaci

Physarum polycephalum is an acellular slime mould that grows as a highly adaptive network of veins filled with protoplasm. As it forages, Physarum dynamically rearranges its network structure as a response to local stimuli information,…

流体动力学 · 物理学 2023-05-23 Rodrigo Almeida , Rui Dilão

The true slime mold \textit{Physarum polycephalum} has the remarkable capability to perform self-organized activities such as network formation among food sources. Despite well reproducing the emergence of slime networks, existing models…

种群与进化 · 定量生物学 2025-08-04 Damiano Reginato , Daniele Proverbio , Giulia Giordano

In this paper we study dynamics inspired by Physarum polycephalum (a slime mold) for solving linear programs [NTY00, IJNT11, JZ12]. These dynamics are arrived at by a local and mechanistic interpretation of the inner workings of the slime…

数据结构与算法 · 计算机科学 2015-11-24 Damian Straszak , Nisheeth K. Vishnoi

True slime mould Physarum polycephalum approximates a range of complex computations via growth and adaptation of its proto- plasmic transport network, stimulating a large body of recent research into how such a simple organism can perform…

新兴技术 · 计算机科学 2015-03-12 Jeff Jones , Andrew Adamatzky

The true slime mould Physarum polycephalum is a recent well studied example of how complex transport networks emerge from simple auto-catalytic and self- organising local interactions, adapting structure and function against changing…

新兴技术 · 计算机科学 2015-03-29 Jeff Jones

Slime mould Physarum polycephalum is large single cell with intriguingly smart behaviour. The slime mould shows outstanding abilities to adapt its protoplasmic network to varying environmental conditions. The slime mould can solve tasks of…

新兴技术 · 计算机科学 2013-04-09 Andrew Adamatzky , Rachel Armstrong , Jeff Jones , Yukio-Pegio Gunji

We present two results on slime mold computations. In wet-lab experiments (Nature'00) by Nakagaki et al. the slime mold Physarum polycephalum demonstrated its ability to solve shortest path problems. Biologists proposed a mathematical…

数据结构与算法 · 计算机科学 2019-07-01 Ruben Becker , Vincenzo Bonifaci , Andreas Karrenbauer , Pavel Kolev , Kurt Mehlhorn

Physarum polycephalum is a single-celled, multi-nucleated slime mold whose body constitutes a network of veins. As it explores its environment, it adapts and optimizes its network to external stimuli. It has been shown to exhibit complex…

流体动力学 · 物理学 2023-09-20 Ana Filipa Valente

The giant single-celled slime mould Physarum polycephalum has inspired rapid develop- ments in unconventional computing substrates since the start of this century. This is primarily due to its simple component parts and the distributed…

新兴技术 · 计算机科学 2015-11-19 Jeff Jones

The slime mould Physarum polycephalum displays adaptive transport dynamics and network formation that have inspired its use as a model of biological computation. We develop a Lagrangian formulation of Physarum's adaptive dynamics on…

神经元与认知 · 定量生物学 2025-11-12 Ricard Solé , Jordi Pla-Mauri

Slime mould \emph{Physarum polycephalum} is a large single cell capable for distributed sensing, concurrent information processing, parallel computation and decentralised actuation. The ease of culturing and experimenting with Physarum…

新兴技术 · 计算机科学 2015-12-29 Andrew Adamatzky

With increasing interest in adaptive clinical trial designs, challenges are present to drug supply chain management which may offset the benefit of adaptive designs. Thus, it is necessary to develop an optimization tool to facilitate the…

应用统计 · 统计学 2023-10-16 Jincheng Pang , Hong Yan , Zoe Hua

The slime mould Physarum polycephalum has been used in developing unconventional computing devices for in which the slime mould played a role of a sensing, actuating, and computing device. These devices treated the slime mould rather as an…

A dynamic self-organized morphology is the hallmark of network-shaped organisms like slime moulds and fungi. Organisms continuously re-organize their flexible, undifferentiated body plans to forage for food. Among these organisms the slime…

生物物理 · 物理学 2019-03-27 Karen Alim

Physarum polycephalum is a large single amoeba cell, which in its plasmodial phase,forages and connects nearby food sources with protoplasmic tubes. The organism forages for food by growing these tubes towards detected food stuffs, this…

新兴技术 · 计算机科学 2014-06-10 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

Plasmodium of true slime mold, Physarum polycephalum, is an amoeboid organism, which spreads with developing tubular network structure and crawls on two-dimensional plane with oscillating the cell thickness. The plasmodium transforms its…

适应与自组织系统 · 物理学 2009-04-10 Yuki Kagawa , Atsuko Takamatsu
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