相关论文: Derivation of a Hele-Shaw type system from a cell …
Mechanical effects have mostly been neglected so far in phase field tumour models that are based on a Cahn-Hilliard approach. In this paper we study a macroscopic mechanical model for tumour growth in which cell-cell adhesion effects are…
We analyse a novel mathematical model of malignant invasion which takes the form of a two-phase moving boundary problem describing the invasion of a population of malignant cells into a population of background tissue, such as skin. Cells…
A plane turbulent mixing in a shear flow of an ideal homogeneous fluid confined between two relatively close rigid walls is considered. The character of the flow is determined by interaction of vortices arising at the nonlinear stage of the…
An asymptotic analysis for a system with equation and dynamic boundary condition of Cahn-Hilliard type is carried out as the coefficient of the surface diffusion acting on the phase variable tends to 0, thus obtaining a forward-backward…
In this paper, we propose a novel free boundary problem to model the movement of single species with a range boundary. The spatial movement and birth/death processes of the species found within the range boundary are assumed to be governed…
A large population limit of the parabolic-parabolic Patlak-Keller-Segel (PKS) system with degenerate, nonlinear diffusion, e.g., of porous medium-type $-\frac{m}{m-1}\mathrm{div}(\rho \nabla \rho^{m-1})$, is studied. We show,…
This paper is a continuation of the work in \cite{kimzhang2024} concerning Hele-Shaw flow with both drift and source terms. We prove that, in a local neighborhood, if the free boundary is Lipschitz continuous with a sufficiently small…
In this paper, we derive a new chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the…
Topology changes in multi-phase fluid flows are difficult to model within a traditional sharp interface theory. Diffuse interface models turn out to be an attractive alternative to model two-phase flows. Based on a…
Collective migration dominates many phenomena, from cell movement in living systems to abiotic self-propelling particles. Focusing on the early stages of tumor evolution, we enunciate the principles involved in cell dynamics and highlight…
A new general class of exact solutions is presented for the time evolution of a bubble of arbitrary initial shape in a Hele-Shaw cell when surface tension effects are neglected. These solutions are obtained by conformal mapping the viscous…
In this paper, the interaction between two immiscible fluids with a finite mobility ratio is investigated numerically within a Hele-Shaw cell. Fingering instabilities initiated at the interface between a low viscosity fluid and a high…
In this paper, we study a system of three evolutionary operator equations involving fractional powers of selfadjoint, monotone, unbounded, linear operators having compact resolvents. This system constitutes a generalization of a phase field…
We report new chemoconvective pattern formation phenomena observed in a two-layer system of miscible fluids filling a vertical Hele-Shaw cell. We show both experimentally and theoretically that the concentration-dependent diffusion coupled…
In this paper we consider two diffuse interface models for tumor growth coupling a Cahn-Hilliard type equation for the tumor phase parameter to a reaction-diffusion type equation for the nutrient. The models are distinguished by the…
We propose a method of construction of exact solutions of free boundary problems corresponding to Hele-Shaw flows in presence of an external field. Such a field may arise, in particular, due to electrokinetic phenomena. Both a general…
Epithelization, the process whereby an epithelium covers a cell-free surface, is not only central to wound healing but also pivotal in embryonic morphogenesis, regeneration, and cancer. In the context of wound healing, the epithelization…
In this work, we develop a structure-preserving numerical scheme for a Cahn-Hilliard-Darcy model that describes tumor growth in a fluid-saturated porous medium. First, we derive a physically consistent model from the general framework…
We analyze the contact Hele-Shaw problem with zero surface tension of a free boundary in a thin domain $\Omega^{\varepsilon}(t).$ Under suitable conditions on the given data, the one-valued local classical solvability of the problem for…
We investigate a generalized Hele-Shaw equation with a source and drift terms where the density is constrained by an upper-bound density constraint that varies in space and time. By using a generalized porous medium equation approximation,…