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One of the main aims of phylogenetics is to reconstruct the \enquote{Tree of Life}. In this respect, different methods and criteria are used to analyze DNA sequences of different species and to compare them in order to derive the…

种群与进化 · 定量生物学 2018-10-05 Michelle Galla , Kristina Wicke , Mareike Fischer

Most current methods for inferring species-level phylogenies under the coalescent model assume that no gene flow occurs following speciation. While some studies have examined the impact of gene flow on estimation accuracy for certain…

种群与进化 · 定量生物学 2017-10-12 Colby Long , Laura Kubatko

Lineage tracing, the tracking of living cells as they move and divide, is a central problem in biological image analysis. Solutions, called lineage forests, are key to understanding how the structure of multicellular organisms emerges. We…

计算机视觉与模式识别 · 计算机科学 2017-10-03 Florian Jug , Evgeny Levinkov , Corinna Blasse , Eugene W. Myers , Bjoern Andres

Trees corresponding to $\Lambda$- and $\Xi$-$n$-coalescents can be both quite similar and fundamentally different compared to bifurcating tree models based on Kingman's $n$-coalescent. This has consequences for inference of a well-fitting…

概率论 · 数学 2020-10-26 Fabian Freund

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

种群与进化 · 定量生物学 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

One of the goals of phylogenetic research is to find the species tree describing the evolutionary history of a set of species. But the trees derived from geneti data with the help of tree inference methods are gene trees that need not…

种群与进化 · 定量生物学 2015-07-28 Mareike Fischer , Martin Kreidl

The $\text{NJ}_{st}$ method was proposed by Liu and Yu to infer a species tree topology from unrooted topological gene trees. While its statistical consistency under the multispecies coalescent model was established only for a 4-taxon tree,…

种群与进化 · 定量生物学 2016-04-20 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

As genomic scale datasets motivate research on species tree inference, simulators of the multispecies coalescent (MSC) process are essential for the testing and evaluation of new inference methods. However, the simulators themselves must be…

种群与进化 · 定量生物学 2019-08-06 Elizabeth S. Allman , Hector Baños , John A. Rhodes

The \emph{maximum a posteriori} (MAP) assignment for general structure Markov random fields (MRFs) is computationally intractable. In this paper, we exploit tree-based methods to efficiently address this problem. Our novel method, named…

人工智能 · 计算机科学 2014-07-23 Truyen Tran , Dinh Phung , Svetha Venkatesh

We propose a statistical method to test whether two phylogenetic trees with given alignments are significantly incongruent. Our method compares the two distributions of phylogenetic trees given by the input alignments, instead of comparing…

种群与进化 · 定量生物学 2010-04-14 Elissaveta Arnaoudova , David Haws , Peter Huggins , Jerzy W. Jaromczyk , Neil Moore , Chris Schardl , Ruriko Yoshida

We consider a model of a population in which individuals are sampled from different species. The Yule-Kingman nested coalescent describes the genealogy of the sample when each species merges with another randomly chosen species with a…

概率论 · 数学 2023-12-20 Toni Gui

The reconstruction of phylogenetic networks is an important but challenging problem in phylogenetics and genome evolution, as the space of phylogenetic networks is vast and cannot be sampled well. One approach to the problem is to solve the…

种群与进化 · 定量生物学 2023-04-14 Louxin Zhang , Niloufar Abhari , Caroline Colijn , Yufeng Wu

Traditionally, phylogeny and sequence alignment are estimated separately: first estimate a multiple sequence alignment and then infer a phylogeny based on the sequence alignment estimated in the previous step. However, uncertainty in the…

应用统计 · 统计学 2014-11-25 Heejung Shim , Bret Larget

Coalescent models of evolution account for incomplete lineage sorting by specifying a species tree parameter which determines a distribution on gene trees. It has been shown that the unrooted topology of the species tree parameter of the…

种群与进化 · 定量生物学 2017-01-25 Colby Long , Laura Kubatko

This paper develops a novel nested sequent proof-search methodology for intuitionistic tense logics (ITLs), supporting finite counter-model extraction. We introduce a new loop-checking method that detects repeating nested sequents using…

计算机科学中的逻辑 · 计算机科学 2026-04-01 Tim S. Lyon

Coalescent histories are combinatorial structures that describe for a given gene tree and species tree the possible lists of branches of the species tree on which the gene tree coalescences take place. Properties of the number of coalescent…

种群与进化 · 定量生物学 2015-03-13 Filippo Disanto , Noah A. Rosenberg

We provide time- and sample-efficient algorithms for learning and testing latent-tree Ising models, i.e. Ising models that may only be observed at their leaf nodes. On the learning side, we obtain efficient algorithms for learning a…

机器学习 · 计算机科学 2023-07-11 Davin Choo , Yuval Dagan , Constantinos Daskalakis , Anthimos Vardis Kandiros

Reconciliation methods aim at recovering macro evolutionary events and at localizing them in the species history, by observing discrepancies between gene family trees and species trees. In this article we introduce an Integer Linear…

种群与进化 · 定量生物学 2014-10-28 Leo van Iersel , Celine Scornavacca , Steven Kelk

Recently, there has been interest in extending long-known results about the multispecies coalescent tree to other models of gene trees. Results about the gene duplication and loss (GDL) tree have mathematical proofs, including species tree…

种群与进化 · 定量生物学 2024-04-01 Brandon Legried

To introduce selection into a model of coalescence, I explore the use of modified integer partitions that allow the identification of a preferred lineage. I show that a partition-partition transition matrix, along with Monte Carlo discrete…

种群与进化 · 定量生物学 2017-01-05 Irwin Kuntz