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Single-nucleotide-resolution chemical mapping for structured RNA is being rapidly advanced by new chemistries, faster readouts, and coupling to computational algorithms. Recent tests have shown that selective 2'-hydroxyl acylation by primer…

定量方法 · 定量生物学 2011-09-08 Wipapat Kladwang , Christopher C. VanLang , Pablo Cordero , Rhiju Das

Let $L_n$ be the length of the longest common subsequence of two independent i.i.d. sequences of Bernoulli variables of length $n$. We prove that the order of the standard deviation of $L_n$ is $\sqrt{n}$, provided the parameter of the…

概率论 · 数学 2009-07-30 Jüri Lember , Heinrich Matzinger

Despite the recent progress in genome sequencing and assembly, many of the currently available assembled genomes come in a draft form. Such draft genomes consist of a large number of genomic fragments (scaffolds), whose order and/or…

基因组学 · 定量生物学 2022-05-27 Sergey Aganezov , Pavel Avdeyev , Nikita Alexeev , Yongwu Rong , Max A. Alekseyev

Although both RNA and proteins have densely packed native structures, chain organizations of these two biopolymers are fundamentally different. Motivated by the recent discoveries in chromatin folding that interphase chromosomes have…

软凝聚态物质 · 物理学 2016-12-28 Lei Liu , Changbong Hyeon

This work describes the implementation of a genetic algorithm-based strategy combined with first-principles computations for identifying the structure of the most stable boron 1D structures. We focus our attention on the structure of…

材料科学 · 物理学 2023-08-09 Tomasz Tarkowski , Nevill Gonzalez Szwacki

Due to the lack of long-range order, it remains challenging to characterize the structure of disordered solids and understand the nature of the glass transition. Here we propose a new structural order parameter by taking into account…

软凝聚态物质 · 物理学 2024-08-26 Ding Xu , Qinyi Liao , Ning Xu

When interfaces between ordered domains are ordered clusters, frustration disappears. A phase with mixed ordered structures emerges but no length scale can be associated to. We show that sum of densities of each structure plays the role of…

统计力学 · 物理学 2010-05-13 Y. Boughaleb , M. Noureddine , R. Nassif

This paper develops an analogy between the cycle structure of, on the one hand, random permutations with cycle lengths restricted to lie in an infinite set $S$ with asymptotic density $\sigma$ and, on the other hand, permutations selected…

组合数学 · 数学 2009-08-07 Michael Lugo

Many systems in nature and the synthetic world involve ordered arrangements of units on two-dimensional surfaces. We review here the fundamental role payed by both the topology of the underlying surface and its detailed curvature. Topology…

软凝聚态物质 · 物理学 2009-07-31 Mark J. Bowick , Luca Giomi

Let $\Pi_q$ be an arbitrary finite projective plane of order $q$. A subset $S$ of its points is called saturating if any point outside $S$ is collinear with a pair of points from $S$. Applying probabilistic tools we improve the upper bound…

组合数学 · 数学 2017-11-28 Zoltán Lóránt Nagy

The GOR program for predicting protein secondary structure is extended to include triple correlation. A score system for a residue pair to be at certain conformation state is derived from the conditional weight matrix describing amino acid…

生物物理 · 物理学 2007-05-23 Xin Liu , Li-mei Zhang , Wei-Mou Zheng

Resonant soft X-ray scattering was used to determine the presence of more subtle orderings not detected in standard structural analyses. By tuning to specific Co absorption edges, arrangements particular to the electronic states of those…

强关联电子 · 物理学 2017-07-17 F. J. Rueckert , F. He , B. Poudel , B. Dabrowski , W. A. Hines , J. I. Budnick , B. O. Wells

In this paper we present a sampling framework for RNA structures of fixed topological genus. We introduce a novel, linear time, uniform sampling algorithm for RNA structures of fixed topological genus $g$, for arbitrary $g>0$. Furthermore…

计算工程、金融与科学 · 计算机科学 2013-04-30 Fenix W. D. Huang , Markus E. Nebel , Christian M. Reidys

We establish a general result about extending a right invertible row over a Banach algebra to an invertible matrix. This is applied to the computation of right topological stable rank of a split exact sequence. We also introduce a…

算子代数 · 数学 2014-02-26 Kenneth R. Davidson , You Qing Ji

We study a circular order on labelled, m-edge-coloured trees with k vertices, and show that the set of such trees with a fixed circular order is in bijection with the set of RNA m-diagrams of degree k, combinatorial objects which can be…

组合数学 · 数学 2020-12-21 Bethany Marsh , Sibylle Schroll

Let $X_1, X_2,\ldots, X_n$ (resp. $Y_1, Y_2,\ldots, Y_n$) be independent random variables such that $X_i$ (resp. $Y_i$) follows generalized exponential distribution with shape parameter $\theta_i$ and scale parameter $\lambda_i$ (resp.…

应用统计 · 统计学 2016-01-18 Amarjit Kundu , Shovan Chowdhury , Asok K. Nanda , Nil Kamal Hazra

We show that the expected size of the maximum agreement subtree of two $n$-leaf trees, uniformly random among all trees with the shape, is $\Theta(\sqrt{n})$. To derive the lower bound, we prove a global structural result on a decomposition…

组合数学 · 数学 2018-09-13 Pratik Misra , Seth Sullivant

We show that the diameter of the directed configuration model with $n$ vertices rescaled by $\log n$ converges in probability to a constant. Our assumptions are the convergence of the in- and out-degree of a uniform random vertex in…

概率论 · 数学 2020-03-12 Xing Shi Cai , Guillem Perarnau

We present a dynamic data structure for representing binary $n\times n$ matrices that are $d$-twin-ordered, for a~fixed parameter $d$. Our structure supports cell queries and single-cell updates both in $\Oh(\log \log n)$ expected worst…

Transfer systems are combinatorial objects which classify $N_\infty$ operads up to homotopy. By results of A. Blumberg and M. Hill, every transfer system associated to a linear isometries operad is also saturated (closed under a particular…

代数拓扑 · 数学 2021-09-20 Usman Hafeez , Peter Marcus , Kyle Ormsby , Angélica Osorno