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Assessing the practical identifiability of epidemic models is essential for determining whether parameters can be meaningfully estimated from observed data. Monte Carlo (MC) methods provide an accessible and intuitive framework; however,…

统计方法学 · 统计学 2025-10-01 Chiara Mattamira , Olivia Prosper Feldman

We consider a continuous-time Markov chain model of SIR disease dynamics with two levels of mixing. For this so-called stochastic households model, we provide two methods for inferring the model parameters---governing within-household…

种群与进化 · 定量生物学 2018-02-07 James N. Walker , Joshua V. Ross , Andrew J. Black

In this work, we study the evolution of the susceptible individuals during the spread of an epidemic modeled by the susceptible-infected-recovered (SIR) process spreading on the top of complex networks. Using an edge-based compartmental…

物理与社会 · 物理学 2012-09-25 L. D. Valdez , P. A. Macri , L. A. Braunstein

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

统计方法学 · 统计学 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

This paper presents a discrete time probabilistic dynamic for simulating a contact-based epidemic spreading based on discrete time Markov chain process, in particular the attention is addressed to the susceptible-infectious-removed (SIR)…

物理与社会 · 物理学 2017-12-22 Fabrizio Angaroni

Different strains competing for a common pool of susceptible individuals is a key problem in mathematical epidemiology. To address this problem, we investigate a two-strain model within a Susceptible-Infected-Recovered (SIR) framework.…

种群与进化 · 定量生物学 2026-04-28 Enrique C. Gabrick , Ana Luiza de Moraes , Ervin K. Lenzi , Iberê L. Caldas

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

Threshold theorem is probably the most important development of mathematical epidemic modelling. Unfortunately, some models may not behave according to the threshold. In this paper, we will focus on the final outcome of SIR model with…

种群与进化 · 定量生物学 2018-03-06 Kurnia Susvitasari

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

应用统计 · 统计学 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

In this paper we consider a stochastic SEIQR (susceptible-exposed-infected-quarantined-recovered) epidemic model with a generalized incidence function. Using the Lyapunov method, we establish the existence and uniqueness of a global…

种群与进化 · 定量生物学 2025-01-31 Brahim Boukanjime , Mohamed Maama

In this study, we propose a time-dependent Susceptible-Exposed-Infected-Recovered (SEIR) model for the analysis of the SARS-CoV-2 epidemic outbreak in three different countries, the United States of America, Italy and Iceland using public…

种群与进化 · 定量生物学 2021-11-08 P. Girardi , C. Gaetan

Here we propose and implement a generalized mathematical model to find the time evolution of population in infectious diseases and apply the model to study the recent COVID-19 pandemic. Our model at the core is a non-local generalization of…

种群与进化 · 定量生物学 2020-05-01 Saumyak Mukherjee , Sayantan Mondal , Biman Bagchi

Global pandemics, such as the recent COVID-19 crisis, highlight the need for stochastic epidemic models that can capture the randomness inherent in the spread of disease. Such models must be accompanied by methods for estimating parameters…

定量方法 · 定量生物学 2026-04-13 Vincent Wieland , Nils Wassmuth , Lorenzo Contento , Martin Kühn , Jan Hasenauer

A stochastic SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a social network is analysed. The underlying social network is described by an Erd\H{o}s-R\'{e}nyi random graph but, during the course of the epidemic,…

概率论 · 数学 2020-08-17 Frank Ball , Tom Britton

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

种群与进化 · 定量生物学 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

We examine the age-structured SIR model, a variant of the classical Susceptible-Infected-Recovered (SIR) model of epidemic propagation, in the context of COVID-19. In doing so, we provide a theoretical basis for the model, perform an…

最优化与控制 · 数学 2022-03-11 Rohit Parasnis , Ryosuke Kato , Amol Sakhale , Massimo Franceschetti , Behrouz Touri

We consider Markovian susceptible-infectious-removed (SIR) dynamics on time-invariant weighted contact networks where the infection and removal processes are Poisson and where network links may be directed or undirected. We prove that a…

种群与进化 · 定量生物学 2013-12-19 Kieran J. Sharkey , Istvan Z. Kiss , Robert R. Wilkinson , Peter L. Simon

In contrast to the common assumption in epidemic models that the rate of infection between individuals is constant, in reality, an individual's viral load determines their infectiousness. We compare the average and individual reproductive…

种群与进化 · 定量生物学 2021-12-07 Nicholas Landry

We study the Susceptible-Infected-Recovered (SIR) and the Susceptible-Exposed-Infected-Recovered (SEIR) models of epidemics, with possibly time-varying rates, on a class of networks that are locally tree-like, which includes sparse…

概率论 · 数学 2023-09-22 Juniper Cocomello , Kavita Ramanan

The recent COVID-19 pandemic has shown that when the reproduction number is high and there are no proper measurements in place, the number of infected people can increase dramatically in a short time, producing a phenomenon that many…

种群与进化 · 定量生物学 2022-09-20 Jonathan A. Chávez Casillas