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Seasonal variation in environmental variables, and in rates of contact among individuals, are fundamental drivers of infectious disease dynamics. Unlike most periodically-forced physical systems, for which the precise pattern of forcing is…

种群与进化 · 定量生物学 2019-08-09 Irena Papst , David J. D. Earn

We consider state and parameter estimation for compartmental models having both time-varying and time-invariant parameters. Though the described Bayesian computational framework is general, we look at a specific application to the…

计算工程、金融与科学 · 计算机科学 2023-11-07 Brandon Robinson , Philippe Bisaillon , Jodi D. Edwards , Tetyana Kendzerska , Mohammad Khalil , Dominique Poirel , Abhijit Sarkar

Compartmental models, especially the Susceptible-Infected-Removed (SIR) model, have long been used to understand the behaviour of various diseases. Allowing parameters, such as the transmission rate, to be time-dependent functions makes it…

统计方法学 · 统计学 2024-09-27 Son Luu , Edward Susko , Lam Si Tung Ho

The susceptible-infectious-recovered (SIR) model describes the evolution of three species of individuals which are subject to an infection and recovery mechanism. A susceptible $S$ can become infectious with an infection rate $\beta$ by an…

统计力学 · 物理学 2008-06-30 Gunter M. Schütz , Marian Brandau , Steffen Trimper

Using a stochastic Susceptible-Infected-Removed (SIR) meta-population model of disease transmission, we present analytical calculations and numerical simulations dissecting the interplay between stochasticity and the division of a…

种群与进化 · 定量生物学 2020-12-17 Philip Bittihn , Ramin Golestanian

We present an exact analytical solution to a one-dimensional model of the Susceptible-Infected-Recovered (SIR) epidemic type, with infection rates dependent on nearest-neighbor occupations. We use a quantum mechanical approach, transforming…

统计力学 · 物理学 2015-05-30 H. Thomas Williams , Irina Mazilu , Dan Mazilu

Estimation of epidemiological and population parameters from molecular sequence data has become central to the understanding of infectious disease dynamics. Various models have been proposed to infer details of the dynamics that describe…

种群与进化 · 定量生物学 2014-12-25 Alex Popinga , Tim Vaughan , Tanja Stadler , Alexei Drummond

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

种群与进化 · 定量生物学 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

We introduce a stochastic SIR-type partial differential equation model incorporating random diffusion, reinfection, vital dynamics, and a randomly varying transmission rate. For the associated random dynamical system, we prove the existence…

Our study is based on an epidemiological compartmental model, the SIRS model. In the SIRS model, each individual is in one of the states susceptible (S), infected(I) or recovered (R), depending on its state of health. In compartment R, an…

种群与进化 · 定量生物学 2023-05-10 Michael Bestehorn , Thomas M. Michelitsch

We propose a stochastic SIR model, specified as a system of stochastic differential equations, to analyse the data of the Italian COVID-19 epidemic, taking also into account the under-detection of infected and recovered individuals in the…

种群与进化 · 定量生物学 2021-02-22 Sara Pasquali , Antonio Pievatolo , Antonella Bodini , Fabrizio Ruggeri

We investigate an epidemic model based on Bailey's continuous differential system. In the continuous time domain, we extend the classical model to time-dependent coefficients and present an alternative solution method to Gleissner's…

经典分析与常微分方程 · 数学 2019-01-01 Martin Bohner , Sabrina Streipert , Delfim F. M. Torres

We present a new Bayesian inference method for compartmental models that takes into account the intrinsic stochasticity of the process. We show how to formulate a SIR-type Markov jump process as the solution of a stochastic differential…

统计方法学 · 统计学 2020-04-23 Benjamin Nguyen-Van-Yen , Pierre Del Moral , Bernard Cazelles

The impact of spatial structure on the spread of an epidemic is an important issue in the propagation of infectious diseases. Recent studies, both deterministic and stochastic, have made it possible to understand the importance of the…

概率论 · 数学 2023-01-09 Alphonse Emakoua

Consider a large uniformly mixing dynamic population, which has constant birth rate and exponentially distributed lifetimes, with mean population size $n$. A Markovian SIR (susceptible $\to$ infective $\to$ recovered) infectious disease,…

概率论 · 数学 2015-06-09 Frank Ball , Tom Britton , Pieter Trapman

Waiting times between two consecutive infection and recovery events in spreading processes are often assumed to be exponentially distributed, which results in Markovian (i.e., memoryless) continuous spreading dynamics. However, this is not…

物理与社会 · 物理学 2020-07-27 Lucas Böttcher , Nino Antulov-Fantulin

We present a modelling framework for the spreading of epidemics on temporal networks from which both the individual-based and pair-based models can be recovered. The proposed temporal pair-based model that is systematically derived from…

物理与社会 · 物理学 2020-11-17 Rory Humphries , Kieran Mulchrone , Jamie Tratalos , Simon More , Philipp Hövel

Multidimensional continuous-time Markov jump processes $(Z(t))$ on $\mathbb{Z}^p$ form a usual set-up for modeling $SIR$-like epidemics. However, when facing incomplete epidemic data, inference based on $(Z(t))$ is not easy to be achieved.…

统计方法学 · 统计学 2014-01-03 Romain Guy , Catherine Larédo , Elisabeta Vergu

In the recent COVID-19 pandemic we assisted at a sequence of epidemic waves intertwined by anomalous fade-outs with periods of low but persistent epidemic prevalence. These long-living epidemic states complicate epidemic control and…

物理与社会 · 物理学 2025-08-27 Javier Aguilar , Beatriz Arregui García , Raúl Toral , Sandro Meloni , Jose J. Ramasco

Stochastic epidemic models provide an interpretable probabilistic description of the spread of a disease through a population. Yet, fitting these models to partially observed data is a notoriously difficult task due to intractability of the…

统计计算 · 统计学 2022-10-21 Raphael Morsomme , Jason Xu