相关论文: Starr: Simple Tiling Array Analysis of Affymetrix …
Precision medicine is a paradigm shift in healthcare relying heavily on genomics data. However, the complexity of biological interactions, the large number of genes as well as the lack of comparisons on the analysis of data, remain a…
A novel simultaneously transmitting and reflecting (STAR) system design relying on reconfigurable intelligent surfaces (RISs) is conceived. First, an existing prototype is reviewed and the potential benefits of STAR-RISs are discussed.…
The current trend for domain-specific architectures (DSAs) has led to renewed interest in research test chips to demonstrate new specialized hardware. Tape-outs also offer huge pedagogical value garnered from real hands-on exposure to the…
The different elemental abundances of the photosphere and the corona are striking features of not only the Sun, but other stars as well. This phenomenon is known as the FIP effect (FIP stands for first ionization potential), and its…
Background: Over the last years, more and more biological data became available. Besides the pure amount of new data, also its dimensionality - the number of different attributes per data point - increased. Recently, especially the amount…
The interAdapt R package is designed to be used by statisticians and clinical investigators to plan randomized trials. It can be used to determine if certain adaptive designs offer tangible benefits compared to standard designs, in the…
The STAR experiment at the Relativistic Heavy Ion Collider (RHIC) has a rich spin physics program aimed at exploring the spin structure of the proton with polarized proton beams. In addition to the currently accessible channels, heavy…
Photoactivatable ribonucleoside-enhanced cross-linking and immunoprecipitation (PAR-CLIP) is an experimental method based on next-generation sequencing for identifying the RNA interaction sites of a given protein. The method deliberately…
The identification of essential proteins in protein-protein interaction networks (PINs) can help to discover drug targets and prevent disease. In order to improve the accuracy of the identification of essential proteins, researchers…
DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA…
Antibodies are widely used in life-sciences and medical therapy. Yet, broadly applicable methods are missing to determine, in the biological system of choice, antibody specificity and its quantitative contribution to e.g. immunofluorescence…
We present STAR: a novel system aimed at solving the complex issue of "p-hacking" and false discoveries in scientific studies. STAR provides a concrete way for ensuring the application of false discovery control procedures in hypothesis…
Motivation: Usefulness of analysis derived from Affymetrix microarrays depends largely upon the reliability of files describing the correspondence between probe sets, genes and transcripts. In particular, in case a gene is targeted by two…
DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important.…
A variety of genome-wide profiling techniques are available to probe complementary aspects of genome structure and function. Integrative analysis of heterogeneous data sources can reveal higher-level interactions that cannot be detected…
Thermal infrared (TIR) target tracking methods often adopt the correlation filter (CF) framework due to its computational efficiency. However, the low resolution of TIR images, along with tracking interference, significantly limits the…
In microarray experiments, it is often of interest to identify genes which have a pre-specified gene expression profile with respect to time. Methods available in the literature are, however, typically not stringent enough in identifying…
Genome-scale screening experiments in cancer produce long lists of candidate genes that require extensive interpretation for biological insight and prioritization for follow-up studies. Interrogation of gene lists frequently represents a…
This book chapter reviews progress in crystallographic image processing (CIP) for scanning probe microscopy (SPM) that has occurred since our description of the technique was first put into open access in this book series in the year 2010.…
Investigations of elemental abundances in the ancient and most metal deficient stars are extremely important because they serve as tests of variable nucleosynthesis pathways and can provide critical inferences of the type of stars that…