中文
相关论文

相关论文: Identifiability of 2-tree mixtures for group-based…

200 篇论文

We compare the phylogenetic tensors for various trees and networks for two, three and four taxa. If the probability spaces between one tree or network and another are not identical then there will be phylogenetic tensors that could have…

种群与进化 · 定量生物学 2016-06-24 Jonathan Mitchell

A foundational question in the theory of linear compartmental models is how to assess whether a model is structurally identifiable -- that is, whether parameter values can be inferred from noiseless data -- directly from the combinatorics…

动力系统 · 数学 2024-02-19 Cashous Bortner , Elizabeth Gross , Nicolette Meshkat , Anne Shiu , Seth Sullivant

We prove identifiability of parameters for a broad class of random graph mixture models. These models are characterized by a partition of the set of graph nodes into latent (unobservable) groups. The connectivities between nodes are…

统计理论 · 数学 2010-06-07 Elizabeth S. Allman , Catherine Matias , John A. Rhodes

Mutation rate variation across loci is well known to cause difficulties, notably identifiability issues, in the reconstruction of evolutionary trees from molecular sequences. Here we introduce a new approach for estimating general…

概率论 · 数学 2011-09-30 Elchanan Mossel , Sebastien Roch

The general Markov plus invariable sites (GM+I) model of biological sequence evolution is a two-class model in which an unknown proportion of sites are not allowed to change, while the remainder undergo substitutions according to a Markov…

种群与进化 · 定量生物学 2011-11-10 Elizabeth S. Allman , John A. Rhodes

Phylogenetic networks are an extension of phylogenetic trees which are used to represent evolutionary histories in which reticulation events (such as recombination and hybridization) have occurred. A central question for such networks is…

种群与进化 · 定量生物学 2018-03-28 Andrew Francis , Vincent Moulton

Phylogenetic networks extend phylogenetic trees to model non-vertical inheritance, by which a lineage inherits material from multiple parents. The computational complexity of estimating phylogenetic networks from genome-wide data with…

种群与进化 · 定量生物学 2022-06-28 Jingcheng Xu , Cécile Ané

The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories,…

概率论 · 数学 2012-11-30 Elchanan Mossel , Sebastien Roch

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

种群与进化 · 定量生物学 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

Inference of species networks from genomic data under the Network Multispecies Coalescent Model is currently severely limited by heavy computational demands. It also remains unclear how complicated networks can be for consistent inference…

种群与进化 · 定量生物学 2022-05-10 Elizabeth S. Allman , Hector Baños , Jonathan D. Mitchell , John A. Rhodes

For a pair consisting of a gene tree and a species tree, the ancestral configurations at an internal node of the species tree are the distinct sets of gene lineages that can be present at that node. Ancestral configurations appear in…

组合数学 · 数学 2020-06-17 Filippo Disanto , Michael Fuchs , Ariel R. Paningbatan , Noah A. Rosenberg

This paper explores unsupervised learning of parsing models along two directions. First, which models are identifiable from infinite data? We use a general technique for numerically checking identifiability based on the rank of a Jacobian…

机器学习 · 统计学 2012-06-15 Daniel Hsu , Sham M. Kakade , Percy Liang

The reconstruction of phylogenetic trees from mixed populations has become important in the study of cancer evolution, as sequencing is often performed on bulk tumor tissue containing mixed populations of cells. Recent work has shown how to…

数据结构与算法 · 计算机科学 2016-04-12 Mohammed El-Kebir , Gryte Satas , Layla Oesper , Benjamin J. Raphael

The inference of the evolutionary history of a collection of organisms is a problem of fundamental importance in evolutionary biology. The abundance of DNA sequence data arising from genome sequencing projects has led to significant…

种群与进化 · 定量生物学 2015-07-07 Julia Chifman , Laura Kubatko

In mathematical phylogenetics, evolutionary relationships are often represented by trees and networks. The latter are typically used whenever the relationships cannot be adequately described by a tree, which happens when so-called…

种群与进化 · 定量生物学 2025-12-05 Mirko Wilde , Mareike Fischer

Identifiability of the discrete tree parameter is a key property for phylogenetic models since it is necessary for statistically consistent estimation of the tree from sequence data. Algebraic methods have proven to be very effective at…

种群与进化 · 定量生物学 2023-03-22 Jane Ivy Coons , Benjamin Hollering

Species trees represent the historical divergences of populations or species, while gene trees trace the ancestry of individual gene copies sampled within those populations. In cases involving rapid speciation, gene trees with topologies…

种群与进化 · 定量生物学 2015-08-28 James H. Degnan , John A. Rhodes

Recent work has shown that finite mixture models with $m$ components are identifiable, while making no assumptions on the mixture components, so long as one has access to groups of samples of size $2m-1$ which are known to come from the…

统计理论 · 数学 2022-07-25 Robert A. Vandermeulen , René Saitenmacher

Given a gene-tree labeled topology $G$ and a species tree $S$, the "ancestral configurations" at an internal node $k$ of $S$ represent the combinatorially different sets of gene lineages that can be present at $k$ when all possible…

In phylogenetics, a central problem is to infer the evolutionary relationships between a set of species $X$; these relationships are often depicted via a phylogenetic tree -- a tree having its leaves univocally labeled by elements of $X$…

数据结构与算法 · 计算机科学 2016-04-12 Julien Baste , Christophe Paul , Ignasi Sau , Celine Scornavacca