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The high frequency collective dynamics of liquid hydrogen fluoride is studied by inelastic x-ray scattering on the coexistence curve at T = 239 K. The comparison with existing molecular dynamics simulations shows the existence of two active…

软凝聚态物质 · 物理学 2023-08-29 R. Angelini , P. Giura , G. Monaco , G. Ruocco , F. Sette , R. Verbeni

We discuss relaxation and aging processes in the one- and two-dimensional $ABC$ models. In these driven diffusive systems of three particle types, biased exchanges in one direction yield a coarsening process characterized in the long time…

统计力学 · 物理学 2015-05-13 Mark O. Brown , Robert H. Galyean , Xiangwen Wang , Michel Pleimling

A low-temperature dynamical transition has been reported in several proteins. We provide the first observation of a `protein-like' dynamical transition in nonbiological aqueous environments. To this aim we exploit the popular colloidal…

Concentrated aqueous solutions of the protein lysozyme undergo a liquid solid transition upon a temperature quench into the unstable spinodal region below a characteristic arrest temperature of Tf=15C. We use video microscopy and…

软凝聚态物质 · 物理学 2015-05-13 Thomas Gibaud , Peter Schurtenberger

We elucidate the physics of the dynamical transition via 10-100ns molecular dynamics simulations at temperatures spanning 160-300K. By tracking the energy fluctuations, we show that the protein dynamical transition is marked by a cross-over…

定量方法 · 定量生物学 2009-06-17 Osman Burak Okan , Ali Rana Atilgan , Canan Atilgan

We propose a method for obtaining the intrinsic, long time mean square displacement (MSD) of atoms and molecules in proteins from finite time molecular dynamics (MD) simulations. Typical data from simulations are limited to times of 1 to 10…

生物物理 · 物理学 2015-06-17 Derya Vural , Liang Hong , Jeremy C. Smith , Henry R. Glyde

Many proteins undergo conformational changes during their activity. A full understanding of the function of these proteins can only be obtained if different conformations and transitions between them can be monitored in aqueous solution,…

We using differential scanning calorimetry of the unfolding process to identify conditions in which the pseudo two-state refolding of thermally denatured lysozyme can be observed to occur on time scales of hours, in solutions that approach…

软凝聚态物质 · 物理学 2013-11-27 Zuofeng Zhao , C. Austen Angell

Logarithmic oscillations superimposed on a power-law trend appear in the behavior of various complex hierarchical systems. In this paper, we study the logarithmic oscillations of relaxation curves in p-adic diffusion models that are used to…

生物大分子 · 定量生物学 2023-06-02 A. Kh. Bikulov , A. P. Zubarev

We report a molecular dynamics (MD) study of the collective dynamics of a simple monatomic liquid -interacting through a two body potential that mimics that of lithium- across the liquid-glass transition. In the glassy phase we find…

无序系统与神经网络 · 物理学 2009-11-07 T. Scopigno , G. Ruocco , F. Sette , G. Viliani

Coarse-graining of fully atomistic molecular dynamics simulations is a long-standing goal in order to allow the description of processes occurring on biologically relevant timescales. For example, the prediction of pathways, rates and…

生物物理 · 物理学 2020-06-12 Steffen Wolf , Benjamin Lickert , Simon Bray , Gerhard Stock

Fatigue and aging of materials are, in large part, determined by the evolution of the atomic-scale structure in response to strains and perturbations. This coupling between microscopic structure and long time scales remains one of the main…

We investigate the presence of structural collective motions on a picosecond time scale for the heme protein, cytochrome c, as a function of oxidation and hydration, using terahertz (THz) time-domain spectroscopy and molecular dynamics…

生物大分子 · 定量生物学 2015-05-19 Yunfen He , Jing-Yin Chen , Joseph R. Knab , Wenjun Zheng , Andrea G. Markelz

Terahertz time-domain spectroscopy and differential scanning calorimetry were used to study the role of the dynamics of biomolecules decoupled from solvent effects. Lyophilised sucrose exhibited steadily increasing absorption with…

无序系统与神经网络 · 物理学 2023-05-11 Johanna Kölbel , Moritz L. Anuschek , Ivonne Stelzl , Supawan Santitewagun , Wolfgang Frieß , J. Axel Zeitler

Interactions between actin, an anionic polyelectrolyte, and lysozyme, a cationic globular protein, have been examined using a combination of synchrotron small-angle x-ray scattering and molecular dynamics simulations. Lysozyme initially…

In this paper the investigation of the dynamical processes of liquid alkali metals is executed by analyzing the time scales of relaxation processes in liquids. The obtained theoretical dynamic structure factor $S(k,\omega)$ for the case of…

无序系统与神经网络 · 物理学 2007-05-23 Anatolii V. Mokshin , Renat M. Yulmetyev , Peter Hänggi

Drying colloidal droplets have a wide range of applications from medical diagnostics to coatings for industries. This paper explores the effects of the substrate temperature (ranging from $25$ to $55 ^{\circ}$C) and various initial…

软凝聚态物质 · 物理学 2021-05-14 Anusuya Pal , Amalesh Gope , Germano S. Iannacchione

We investigate dynamical coupling between water and amino acid side-chain residues in solvation dynamics by selecting residues often used as natural probes, namely tryptophan, tyrosine and histidine, located at different positions on…

生物大分子 · 定量生物学 2017-08-04 Sayantan Mondal , Saumyak Mukherjee , Biman Bagchi

An aqueous suspension of the synthetic clay Laponite undergoes a transition from a liquid-like ergodic state to a glass-like nonergodic arrested state. In an observation that closely resembles the dynamical slowdown observed in supercooled…

软凝聚态物质 · 物理学 2016-10-18 Paramesh Gadige , Debasish Saha , Sanjay Kumar Behera , Ranjini Bandyopadhyay

The process of drying is a simple physical mechanism that drives a system to relax from one equilibrium point to another. The native states of the constituent particles in the droplets can be linked to the emergent morphological patterns…

软凝聚态物质 · 物理学 2021-05-14 Anusuya Pal , Amalesh Gope , Germano S. Iannacchione