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Water plays a major role in bio-systems, greatly contributing to determine their structure, stability and even function. It is well know, for instance, that proteins require a minimum amount of water to be functionally active. Since the…

生物物理 · 物理学 2019-04-05 Antonio Benedetto

The time-dependent relaxation of a dynamical system may exhibit a power-law behavior that is superimposed by log-periodic oscillations. Sornette [Phys. Rep. 297, 239 (1998)] showed that this behavior can be explained by a discrete scale…

生物物理 · 物理学 2023-11-21 Emanuel Dorbath , Adnan Gulzar , Gerhard Stock

A key factor influencing a drug's efficacy is its residence time in the binding pocket of the host protein. Using atomistic computer simulation to predict this residence time and the associated dissociation process is a desirable but…

软凝聚态物质 · 物理学 2015-10-08 Pratyush Tiwary , Jagannath Mondal , Joseph A. Morrone , B. J. Berne

We report a dynamic light scattering study on protein suspensions of bovine lens homogenates at conditions (pH and ionic strength) similar to the physiological ones. Light scattering data were collected at two temperatures, 20 oC and 37 oC,…

软凝聚态物质 · 物理学 2009-11-13 A. Giannopoulou , A. J. Aletras , N. Pharmakakis , G. N. Papatheodorou , S. N. Yannopoulos

Combining elastic incoherent neutron scattering experiments at different resolutions with molecular dynamics simulations, we report the observation of a protein-like dynamical transition in linear chains of Poly(N-isopropylacrylamide). We…

The effects of static electric field on the dynamics of lysozyme and its hydration water have been investigated by means of incoherent quasi-elastic neutron scattering (QENS). Measurements were performed on lysozyme samples, hydrated…

软凝聚态物质 · 物理学 2013-12-09 P. M. Favi , Q. Zhang , H. O'Neill , E. Mamontov , S. O. Diallo

We present a computational investigation on the slow dynamics of a mixture of large and small soft spheres. By varying the size disparity at a moderate fixed composition different relaxation scenarios are observed for the small particles.…

软凝聚态物质 · 物理学 2007-05-23 Angel J. Moreno , Juan Colmenero

Lipid structures exhibit complex and highly dynamic lateral structure; and changes in lipid density and fluidity are believed to play an essential role in membrane targeting and function. The dynamic structure of liquids on the molecular…

软凝聚态物质 · 物理学 2016-12-21 Neda Dadashvand , Christina M. Othon

Protein$\alpha$-helices provide an ordered biological environment that is conducive to soliton-assisted energy transport. The nonlinear interaction between amide I excitons and phonon deformations induced in the hydrogen-bonded lattice of…

生物物理 · 物理学 2022-02-02 Danko D. Georgiev , James F. Glazebrook

The dynamics of self-locomotion of active particles in aligned or liquid crystalline fluids strongly deviates from that in simple isotropic media. We explore the long-time dynamics of a swimmer moving in a three-dimensional smectic liquid…

软凝聚态物质 · 物理学 2018-08-01 Claudia Ferreiro-Córdova , John Toner , Hartmut Löwen , Henricus H. Wensink

In this study, the thermal relaxation of the 20 naturally occurring amino-acids in water is investigated using transient non-equilibrium molecular-dynamics simulations. By modeling the thermal relaxation process, the relaxation times of the…

软凝聚态物质 · 物理学 2023-04-14 Heydar Hamzi , Ali Rajabpour , Édgar Roldán , Ali Hassanali

The relaxation dynamics of a model fluid of platelike colloidal particles is investigated by means of a phenomenological dynamic density functional theory. The model fluid approximates the particles within the Zwanzig model of restricted…

软凝聚态物质 · 物理学 2011-09-14 Markus Bier , Rene van Roij

In this paper, we analyze the dynamics of the Coulomb Glass lattice model in three dimensions near a local equilibrium state by using mean-field approximations. We specifically focus on understanding the role of localization length ($\xi$)…

无序系统与神经网络 · 物理学 2021-03-31 Preeti Bhandari , Vikas Malik , Deepak Kumar , Moshe Schechter

We use computer simulations to study the relaxation dynamics of a model for oil-in-water microemulsion droplets linked with telechelic polymers. This system exhibits both gel and glass phases and we show that the competition between these…

软凝聚态物质 · 物理学 2015-05-29 Pinaki Chaudhuri , Pablo I. Hurtado , Ludovic Berthier , Walter Kob

Pressure provides a powerful parameter to control the protein conformation state, which at sufficiently high values can lead to unfolding. Here, we investigate the effects of increasing pressure up to $0.4$ GPa on hydrated lysozyme…

We investigate theoretically the behavior of proteins as well as other large macromolecules which are incorporated into amphiphilic monolayers at the air-water interface. We assume the monolayer to be in the coexistence region of the…

软凝聚态物质 · 物理学 2007-05-23 R. R. Netz , D. Andelman , H. Orland

The mobility of water molecules confined in a silica pore is studied by computer simulation in the low hydration regime, where most of the molecules reside close to the hydrophilic substrate. A layer analysis of the single particle dynamics…

统计力学 · 物理学 2009-11-10 P. Gallo , M. Rovere

We combine the swap Monte Carlo algorithm to long multi-CPU molecular dynamics simulations to analyse the equilibrium relaxation dynamics of model supercooled liquids over a time window covering ten orders of magnitude for temperatures down…

软凝聚态物质 · 物理学 2022-12-16 Camille Scalliet , Benjamin Guiselin , Ludovic Berthier

In conventional glassformers at sufficiently short times and low enough temperatures, molecules are mutually caged by the intermolecular potential. The fluctuation and dissipation from motion of caged molecules when observed by elastic…

软凝聚态物质 · 物理学 2011-06-30 K. L. Ngai , S. Capaccioli , A. Paciaroni

We present the frequency- and temperature-dependent dielectric properties of lysozyme solutions in a broad concentration regime, measured at subzero temperatures and compare the results with measurements above the freezing point of water…

软凝聚态物质 · 物理学 2015-10-01 M. Wolf , S. Emmert , R. Gulich , P. Lunkenheimer , A. Loidl