离子条件对 DNA 粗粒化模型中打结的影响
软凝聚态物质
2022-12-26 v2
摘要
我们通过蒙特卡洛模拟，在 DNA 的粗粒化 Kratky-Porod 模型中研究长双链 DNA 链的打结概率。通过调整单体的有效直径来实现不同的离子条件。我们发现，高盐条件与平板间限域可显著增强 DNA 中结的出现；类似地，在低盐水情形下结几乎可完全消解。与近期实验的对比证实，该粗粒化模型能够捕捉并定量预测 DNA 的拓扑特征，并可用于指导未来的 DNA 结实验。
引用
@article{arxiv.2211.07326,
title = {Influence of ionic conditions on knotting in a coarse-grained model for DNA},
author = {Sarah Wettermann and Ranajay Datta and Peter Virnau},
journal= {arXiv preprint arXiv:2211.07326},
year = {2022}
}
备注
There were some errors in our manuscript such as mixing up data values from other published papers. Some clarifications were added