相关论文: Microtubules: The neuronic system of the neurons?
The microtubule cytoskeleton is comprised of dynamic, polarized filaments that facilitate transport within the cell. Polarized microtubule arrays are key to facilitating cargo transport in long cells such as neurons. Microtubules also…
In this paper we present an efficient model of the neuronal potentials recorded by a deep brain stimulation microelectrode (DBS MER) in the subthalamic nucleus. It is shown that a computationally efficient filtered point process consisting…
Modern machine learning (ML) systems excel in recognising and classifying images with remarkable accuracy. However, like many computer software systems, they can fail by generating confusing or erroneous outputs or by deferring to human…
The emergence of mental states from neural states by partitioning the neural phase space is analyzed in terms of symbolic dynamics. Well-defined mental states provide contexts inducing a criterion of structural stability for the…
The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…
We consider a new class of non Markovian processes with a countable number of interacting components, both in discrete and continuous time. Each component is represented by a point process indicating if it has a spike or not at a given…
Microscopic two-level systems (TLS) -- ubiquitous atomic-scale defects in solid-state quantum devices -- are a dominant source of qubit decoherence, yet their role is often considered local and short-memoried. Here, we report the…
Increased variability in performance has been associated with the emergence of several neurological and psychiatric pathologies. However, whether and how consistency of neuronal activity may also be indicative of an underlying pathology is…
The Penrose-Hameroff (`Orch OR') model of quantum computation in brain microtubules has been criticized as regards the issue of environmental decoherence. A recent report by Tegmark finds that microtubules can maintain quantum coherence for…
Type 0A string theory in the (2,4k) superconformal minimal model backgrounds, with background ZZ D-branes or R-R fluxes can be formulated non-perturbatively. The branes and fluxes have a description as threshold bound states in an…
The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…
Understanding the intricate operations of Recurrent Neural Networks (RNNs) mechanistically is pivotal for advancing their capabilities and applications. In this pursuit, we propose the Episodic Memory Theory (EMT), illustrating that RNNs…
The fundamental, powerful process of computation in the brain has been widely misunderstood. The paper [1] associates the general failure to build intelligent thinking machines with current reductionist principles of temporal coding and…
In the present paper we describe a model of nonlinear dynamics of microtubules (MT) assuming a single longitudinal degree of freedom per tubulin dimer. This is a longitudinal displacement of a dimer at a certain position with respect to the…
Kinetics of a balanced network of neurons with a sparse grid of synaptic links is well representable by the stochastic dynamics of a generic neuron subject to an effective shot noise. The rate of delta-pulses of the noise is determined…
Nonperturbative effects in string theory are usually associated to D-branes. In many cases it can be explicitly shown that D-brane instantons control the large-order behavior of string perturbation theory, leading to the well-known (2g)!…
The human brain has been studied at multiple scales, from neurons, circuits, areas with well defined anatomical and functional boundaries, to large-scale functional networks which mediate coherent cognition. In a recent work, we addressed…
The actin and microtubule cytoskeletons are vital structures for cell growth and development across all species. While individual molecular mechanisms underpinning actin and microtubule dynamics have been intensively studied, principles…
Artificial neural networks are becoming an integral part of digital solutions to complex problems. However, employing neural networks on quantum processors faces challenges related to the implementation of non-linear functions using quantum…
The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…