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The theory of life history evolution provides a powerful framework to understand the evolutionary dynamics of pathogens in both epidemic and endemic situations. This framework, however, relies on the assumption that pathogen populations are…

种群与进化 · 定量生物学 2017-11-28 Todd Parsons , Amaury Lambert , Troy Day , Sylvain Gandon

We consider SISI epidemic model with discrete-time. The crucial point of this model is that an individual can be infected twice. This non-linear evolution operator depends on seven parameters and we assume that the population size under…

动力系统 · 数学 2020-08-31 Sobirjon Shoyimardonov

We study the early stages of viral infection, and the distribution of times to obtain a persistent infection. The virus population proliferates by entering and reproducing inside a target cell until a sufficient number of new virus…

种群与进化 · 定量生物学 2019-07-11 Carmel Sagi , Michael Assaf

The reconstruction of phylogenetic trees based on viral genetic sequence data sequentially sampled from an epidemic provides estimates of the past transmission dynamics, by fitting epidemiological models to these trees. To our knowledge,…

种群与进化 · 定量生物学 2013-06-17 Amaury Lambert , Helen K. Alexander , Tanja Stadler

This paper studies an epidemic model with nonlocal dispersals. We focus on the influences of initial data and nonlocal dispersals on its spatial propagation. Here the initial data stand for the spatial concentrations of infectious agent and…

偏微分方程分析 · 数学 2020-07-31 Wen-Bing Xu , Wan-Tong Li , Shigui Ruan

We study the dynamics of a spatially structured model of worldwide epidemics and formulate predictions for arrival times of the disease at any city in the network. The model is comprised of a system of ordinary differential equations…

斑图形成与孤子 · 物理学 2018-02-14 Lawrence M. Chen , Matt Holzer , Anne Shapiro

This paper considers a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and varying total population. The interaction of the susceptible and infected people is describe by the…

偏微分方程分析 · 数学 2024-12-13 Rui Peng , Rachidi B. Salako , Yixiang Wu

The time evolution of correlation functions in statistical systems is described by an exact functional differential equation for the corresponding generating functionals. This allows for a systematic discussion of non-equilibrium physics…

高能物理 - 理论 · 物理学 2009-10-30 Christof Wetterich

This paper examines a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and constant total population. The infection mechanism in the model is described by a nonlinear term of the form…

偏微分方程分析 · 数学 2024-12-20 Rui Peng , Rachidi B Salako , Yixiang Wu

A generalisation of the Susceptible-Infectious model is made to include a time-dependent transmission rate, which leads to a close analytical expression in terms of a logistic function. The solution can be applied to any continuous function…

物理与社会 · 物理学 2020-10-08 L. Arturo Urena-Lopez , Alma X. Gonzalez-Morales

Epidemiological models are an important tool in coping with epidemics, as they offer a forecast, even if often simplistic, of the behavior of the disease in the population. This allows responsible health agencies to organize themselves and…

种群与进化 · 定量生物学 2023-08-03 Eliza Maria Ferreira , Ricardo Edem Ferreira , Chiara Mocenni

The fundamental models of epidemiology describe the progression of an infectious disease through a population using compartmentalized differential equations, but do not incorporate population-level heterogeneity in infection susceptibility.…

This article proposes an age-structured compartment model for irreversible diseases with a pre-clinical state of undiagnosed cases that precedes the diagnosis. The model is able to cope with mortality rates differing between the…

种群与进化 · 定量生物学 2014-11-11 Ralph Brinks

We study a simple realistic model for describing the diffusion of an infectious disease on a population of individuals. The dynamics is governed by a single functional delay differential equation, which, in the case of a large population,…

种群与进化 · 定量生物学 2020-09-28 Luca Dell'Anna

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

物理与社会 · 物理学 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta

We study a discrete Susceptible-Infected-Recovered (SIR) model for the spread of infectious disease on a homogeneous tree and the limit behavior of the model in the case when the tree vertex degree tends to infinity. We obtain the…

概率论 · 数学 2022-07-08 Alexander Gairat , Vadim Shcherbakov

Forecasting transmission of infectious diseases, especially for vector-borne diseases, poses unique challenges for researchers. Behaviors of and interactions between viruses, vectors, hosts, and the environment each play a part in…

应用统计 · 统计学 2020-06-02 Stephen A Lauer , Alexandria C Brown , Nicholas G Reich

Epidemic models describe the evolution of a communicable disease over time. These models are often modified to include the effects of interventions (control measures) such as vaccination, social distancing, school closings etc. Many such…

统计方法学 · 统计学 2026-01-27 Heejong Bong , Valérie Ventura , Larry Wasserman

The purpose of this paper is to analyze the mechanism for the interplay of deterministic and stochastic models for contagious diseases. Deterministic models for contagious diseases are prone to predict global stability. Small natural birth…

种群与进化 · 定量生物学 2022-06-17 Torsten Lindström

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

数值分析 · 数学 2025-02-24 Ayesha Baig , Li Zhouxin