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Phylogenetic trees summarize evolutionary relationships between organisms, and tools to analyze collections of phylogenetic trees enable contrasts between different genes' ancestry. The BHV metric space has enabled the analysis of…

定量方法 · 定量生物学 2026-04-24 Maria Alejandra Valdez Cabrera , Amy D Willis

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…

Phylogeny can be inferred using two sources of data from an organism: morphological data and molecular data. Historically, phylogenies were usually inferred using morphological characters, but some morphological features may not necessarily…

种群与进化 · 定量生物学 2023-12-19 Ray Han

Determining associations among different species from citizen science databases is challenging due to observer behavior and intrinsic density variations that give rise to correlations that do not imply species associations. This paper…

种群与进化 · 定量生物学 2025-09-05 Jacob Deutsch

Latent tree analysis seeks to model the correlations among a set of random variables using a tree of latent variables. It was proposed as an improvement to latent class analysis --- a method widely used in social sciences and medicine to…

机器学习 · 计算机科学 2016-10-04 Nevin L. Zhang , Leonard K. M. Poon

Interacting proteins coevolve at multiple but interconnected scales, from the residue-residue over the protein-protein up to the family-family level. The recent accumulation of enormous amounts of sequence data allows for the development of…

生物大分子 · 定量生物学 2019-06-25 Hendrik Szurmant , Martin Weigt

Phylogenies are commonly used to represent the evolutionary relationships between species, and often these phylogenies are equipped with edge lengths that indicate degrees of evolutionary difference. Given such a phylogeny, a popular…

种群与进化 · 定量生物学 2025-02-12 Martin Frohn , Kerry Manson

Phylogenetic analyses of gene expression have great potential for addressing a wide range of questions. These analyses will, for example, identify genes that have evolutionary shifts in expression that are correlated with evolutionary…

种群与进化 · 定量生物学 2014-01-14 Casey W. Dunn , Xi Luo , Zhijin Wu

Molecular phylogeny has focused mainly on improving models for the reconstruction of gene trees based on sequence alignments. Yet, most phylogeneticists seek to reveal the history of species. Although the histories of genes and species are…

种群与进化 · 定量生物学 2013-11-05 Gergely J. Szöllosi , Eric Tannier , Vincent Daubin , Bastien Boussau

Tree shape statistics, particularly measures of tree (im)balance, play an important role in the analysis of the shape of phylogenetic trees. With applications ranging from testing evolutionary models to studying the impact of fertility…

种群与进化 · 定量生物学 2024-10-15 Sophie J. Kersting , Kristina Wicke , Mareike Fischer

Statistical consistency in phylogenetics has traditionally referred to the accuracy of estimating phylogenetic parameters for a fixed number of species as we increase the number of characters. However, as sequences are often of fixed length…

种群与进化 · 定量生物学 2010-04-09 Olivier Gascuel , Mike Steel

We propose a statistical framework to investigate whether a given subpopulation lies between two other subpopulations in a multivariate feature space. This methodology is motivated by a biological question from a collaborator: Is a newly…

统计方法学 · 统计学 2021-03-18 Dustin Pluta , Xiangmin Xu , Daniel L. Gillen , Zhaoxia Yu

Divergence time estimation requires the reconciliation of two major sources of data. These are fossil and/or biogeographic evidence that give estimates of the absolute age of nodes (ancestors) and molecular estimates that give us estimates…

种群与进化 · 定量生物学 2008-12-31 Peter J Waddell

Rank-rank regression is commonly employed in economic research as a way of capturing the relationship between two economic variables. The slope of this regression is the Spearman rank correlation, a classical measure of association.…

计量经济学 · 经济学 2025-10-29 Victor Chernozhukov , Iván Fernández-Val , Jonas Meier , Aico van Vuuren , Francis Vella

Phylogenomics, even more so than traditional phylogenetics, needs to represent the uncertainty in evolutionary trees due to systematic error. Here we illustrate the analysis of genome-scale alignments of yeast, using robust measures of the…

种群与进化 · 定量生物学 2009-12-31 Peter J. Waddell , Ariful Azad

Several formulations are describing the pattern of species-area relationship, log-log linear, semi-log linear, among others. These patterns mainly explain the species-area relationship for large areas, and for the small area, they provide…

种群与进化 · 定量生物学 2021-07-06 Saeid Alirezazadeh , Khadijeh Alibabaei , Stephen P. Hubbell

Interactions among individuals from the same-species of wild animals are an important component of population dynamics. An interaction can be either static (based on overlap of space use) or dynamic (based on movement). The goal of this…

Genetic sequence data of pathogens are increasingly used to investigate transmission dynamics in both endemic diseases and disease outbreaks; such research can aid in development of appropriate interventions and in design of studies to…

定量方法 · 定量生物学 2018-01-24 Hesam Montazeri , Susan Little , Niko Beerenwinkel , Victor DeGruttola

The evolutionary edit distance between two individuals in a population, i.e., the amount of applications of any genetic operator it would take the evolutionary process to generate one individual starting from the other, seems like a…

神经与进化计算 · 计算机科学 2017-05-01 Thomas Gabor , Lenz Belzner

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…