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We present results of numerical self-consistent field (SCF) calculations for the equilibrium mechanical unfolding of a globule formed by a single flexible polymer chain collapsed in a poor solvent. In accordance with earlier scaling theory…

The non-equilibrium structural and dynamical properties of semiflexible polymers confined to two dimensions are investigated by molecular dynamics simulations. Three different scenarios are considered: The force-extension relation of…

软凝聚态物质 · 物理学 2013-01-08 A. Lamura , R. G. Winkler

In this paper we study the role of topology in DNA gel electrophoresis experiments via molecular dynamics simulations. The gel is modelled as a 3D array of obstacles from which half edges are removed at random with probability p, thereby…

软凝聚态物质 · 物理学 2015-04-10 Davide Michieletto , Marco Baiesi , Enzo Orlandini , Matthew S. Turner

We use a series of molecular dynamics simulations, and analytical theory, to demonstrate that a system of hard spheres confined to a narrow cylindrical channel exhibits a continuous phase transition from an isotropic fluid at low densities,…

软凝聚态物质 · 物理学 2014-09-18 Mahdi Zaeifi Yamchi , Richard K. Bowles

Biological organisms often have elongated, flexible structures with some degree of chirality in their bodies or movements. In nature, these organisms frequently take advantage of self-encapsulation mechanisms that create folded…

软凝聚态物质 · 物理学 2024-10-04 Lorenzo Caprini , Iman Abdoli , Umberto Marini Bettolo Marconi , Hartmut Löwen

The contact of a hydrogel during the rotational shearing on glass surface in concentrated polymer solution was observed in situ. Dynamic contact patterns that rotate in-phase with the rotational shearing of the gel were observed for the…

The radius of gyration of a polymer chain immersed in a low molecular weight solvent is known to vary monotonically with the solvent quality. Here, we consider the behavior of a chain immersed in a high molecular weight solvent (polymer…

软凝聚态物质 · 物理学 2007-05-23 Cyprien Gay , Elie Raphael

By means of extensive replica-exchange simulations of generic coarse-grained models for helical polymers, we systematically investigate the structural transitions into all possible helical phases for flexible and semiflexible elastic…

生物物理 · 物理学 2015-09-23 Matthew J. Williams , Michael Bachmann

We use Brownian dynamics simulations and advanced topological profiling methods to characterize the out-of-equilibrium evolution of self-entanglement in linear polymers confined into nano-channels and under periodic compression. We…

软凝聚态物质 · 物理学 2020-06-22 Davide Michieletto , Enzo Orlandini , Matthew S Turner , Cristian Micheletti

We construct a micromechanical version of an early model for topologically constrained polymers -- a 2D chain amongst point-like uncrossable obstacles -- which allows us to explicitly elucidate the role of topological forces beyond…

软凝聚态物质 · 物理学 2022-07-13 Ahmad K. Omar , Yuyuan Lu , Lijia An , Zhen-Gang Wang

Epithelial monolayers are a central building block of complex organisms. Topological defects have emerged as important elements for single cell behavior in flat epithelia. Here we theoretically study such defects in a three-dimensional…

生物物理 · 物理学 2025-02-19 Oliver M. Drozdowski , Ulrich S. Schwarz

We investigate a flexible polymer chain made up of chiral active Brownian particles in two dimensions using computer simulations. In the presence of chiral active Brownian forces, the radius of gyration of the chain reduces significantly.…

软凝聚态物质 · 物理学 2025-05-05 Shalabh K. Anand

The formation of chain-folded structures from the melt is observed in molecular dynamics simulations resembling the lamellae of polymer crystals. Crystallization and subsequent melting temperatures are related linearly to the inverse…

软凝聚态物质 · 物理学 2009-10-31 Hendrik Meyer , Florian Mueller-Plathe

The extent of coupling between the folding of a protein and its binding to a substrate varies from protein to protein. Some proteins have highly structured native states in solution, while others are natively disordered and only fold fully…

软凝聚态物质 · 物理学 2012-05-16 Brenda M. Rubenstein , Ivan Coluzza , Mark A. Miller

Molecular process of crystallization from an oriented amorphous state was reproduced by molecular dynamics simulation for a realistic polyethylene model. Initial oriented amorphous state was obtained by uniaxial drawing an isotropic glassy…

软凝聚态物质 · 物理学 2009-11-07 Akira Koyama , Takashi Yamamoto , Koji Fukao , Yoshihisa Miyamoto

Polymeric particles are strong candidates for designing artificial materials capable of emulating the complex twisting-based functionality observed in biological systems. In this letter, we provide the first detailed investigation of the…

软凝聚态物质 · 物理学 2019-10-16 H. S. Ansell , D. S. Kim , R. D. Kamien , E. Katifori , T. Lopez-Leon

We derive the stochastic equations of motion for a tracer that is tightly attached to a semiflexible polymer and confined or agitated by an externally controlled potential. The generalised Langevin equation, the power spectrum, and the…

软凝聚态物质 · 物理学 2011-11-22 Jakob Tómas Bullerjahn , Sebastian Sturm , Lars Wolff , Klaus Kroy

We combine small angle scattering experiments and simulations to investigate the internal structure and interactions of composite Poly(N-isopropylacrylamide)-Poly(ethylene glycol) (PNIPAM-PEG) microgels. At low temperatures the…

The unfolding of a polymer below the $\theta$ point when pulled by an external force is studied both in d=2 on the lattice and in $d=3$ off lattice. A ground state analysis of finite length chains shows that the globule unfolds via multiple…

统计力学 · 物理学 2009-11-07 D. Marenduzzo , A. Maritan , A. Rosa , F. Seno

The properties of semiflexible polymers tethered by one end to an impenetrable wall and exposed to oscillatory shear flow are investigated by mesoscale simulations. A polymer, confined in two dimensions, is described by a linear bead-spring…

软凝聚态物质 · 物理学 2021-12-14 Antonio Lamura , Roland G. Winkler , Gerhard Gompper