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Predicting drug responses using genetic and transcriptomic features is crucial for enhancing personalized medicine. In this study, we implemented an ensemble of machine learning algorithms to analyze the correlation between genetic and…

基因组学 · 定量生物学 2025-07-04 Johannes Schlüter , Alexander Schönhuth

English words and the outputs of many other natural processes are well-known to follow a Zipf distribution. Yet this thoroughly-established property has never been shown to help compress or predict these important processes. We show that…

Random forest is a classification algorithm well suited for microarray data: it shows excellent performance even when most predictive variables are noise, can be used when the number of variables is much larger than the number of…

定量方法 · 定量生物学 2007-05-23 Ramon Diaz-Uriarte , Sara Alvarez de Andres

Modeling distributions of citations to scientific papers is crucial for understanding how science develops. However, there is a considerable empirical controversy on which statistical model fits the citation distributions best. This paper…

数字图书馆 · 计算机科学 2014-02-18 Michal Brzezinski

In a matching paper (arXiv:1207.5027), I proved that Conservation of Size and Information in a discrete token based system is overwhelmingly likely to lead to a power-law component size distribution with respect to the size of its unique…

信息论 · 计算机科学 2012-09-11 Les Hatton

With the number of sequenced genomes now over one hundred, and the availability of rough functional annotations for a substantial proportion of their genes, it has become possible to study the statistics of gene content across genomes. Here…

生物物理 · 物理学 2007-05-23 Erik van Nimwegen

A curious observation was made that the rank statistics of scientific citation numbers follows Zipf-Mandelbrot's law. The same pow-like behavior is exhibited by some simple random citation models. The observed regularity indicates not so…

物理与社会 · 物理学 2007-05-23 Z. K. Silagadze

We study a deliberately simple, fully non-linguistic model of text: a sequence of independent draws from a finite alphabet of letters plus a single space symbol. A word is defined as a maximal block of non-space symbols. Within this…

计算与语言 · 计算机科学 2025-11-25 Vladimir Berman

Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with trait diversity and disease susceptibility, yet the functional properties of many genetic variants and their molecular…

基因组学 · 定量生物学 2018-03-21 Gary Wilk , Rosemary Braun

In statistics and machine learning, feature selection is the process of picking a subset of relevant attributes for utilizing in a predictive model. Recently, rough set-based feature selection techniques, that employ feature dependency to…

机器学习 · 计算机科学 2020-03-30 Seyedeh Faezeh Farahbakhshian , Milad Taleby Ahvanooey

The importance of statistical patterns of language has been debated over decades. Although Zipf's law is perhaps the most popular case, recently, Menzerath's law has begun to be involved. Menzerath's law manifests in language, music and…

Computational analysis methods including machine learning have a significant impact in the fields of genomics and medicine. High-throughput gene expression analysis methods such as microarray technology and RNA sequencing produce enormous…

基因组学 · 定量生物学 2022-09-28 Nikita Bhandari , Rahee Walambe , Ketan Kotecha , Satyajeet Khare

Classification is one of the major issues in Data Mining Research fields. The classification problems in medical area often classify medical dataset based on the result of medical diagnosis or description of medical treatment by the medical…

人工智能 · 计算机科学 2013-01-09 N. Kalaiselvi , H. Hannah Inbarani

The theory of graphons is an important tool in understanding properties of large networks. We investigate a power-law random graph model and cast it in the graphon framework. The distinctively different structures of the limit graph are…

概率论 · 数学 2022-08-22 Mei Yin

The different between the inverse power function and the negative exponential function is significant. The former suggests a complex distribution, while the latter indicates a simple distribution. However, the association of the power-law…

物理与社会 · 物理学 2018-12-19 Yanguang Chen

When following a sequence - such as reading a text or tracking a user's activity - one can measure how the "dictionary" of distinct elements (types) grows with the number of observations (tokens). When this growth follows a power law, it is…

物理与社会 · 物理学 2026-04-21 Célestin Zimmerlin , Thomas Louail , Manuel Moussallam , Marc Barthelemy

In this second part of our survey on the social and natural distributions, we investigate some models, which intend to explain the statistical regularity of the natural and social distributions. There is a large variety of models and in…

物理与社会 · 物理学 2016-07-05 L. Benguigui , M. Marinov

We address the role of multiplicative stochastic processes in modeling the occurrence of power-law city size distributions. As an explanation of the result of Zipf's rank analysis, Simon's model is presented in a mathematically elementary…

物理与社会 · 物理学 2007-05-23 Damian H. Zanette

DNA Methylation has been the most extensively studied epigenetic mark. Usually a change in the genotype, DNA sequence, leads to a change in the phenotype, observable characteristics of the individual. But DNA methylation, which happens in…

基因组学 · 定量生物学 2018-07-26 Soham Chatterjee , Archana Iyer , Satya Avva , Abhai Kollara , Malaikannan Sankarasubbu

Zipf's law is found when the vocabulary of long written texts is ranked according to the frequency of word occurrences, establishing a power-law decay for the frequency vs rank relation. This law is a robust statistical property observed…

物理与社会 · 物理学 2020-02-17 Juan Ignacio Perotti , Orlando Vito Billoni