相关论文: Does Recycling in Germinal Centers Exist?
Bistability is a major mechanism for cellular decision making and usually results from positive feedback in biochemical control systems. Here we show theoretically that bistability between unbound and bound states of adhesion clusters…
Recycled pulsars are mainly characterized by their spin periods, B-fields and masses. All these quantities are affected by previous interactions with a companion star in a binary system. Therefore, we can use these quantities as fossil…
This paper presents a criterion that provides an easy sufficient condition for a collection of line integrals to have the Chebyshev property. The condition is based on the functions appearing in the line integrals. The criterion is used to…
Given a finite abelian group $G$ and cyclic subgroups $A$, $B$, $C$ of $G$ of the same order, we find necessary and sufficient conditions for $A$, $B$, $C$ to admit a common transversal for the cosets they afford. For an arbitrary number of…
The problem of unicellular-multicellular transition is one of the main issues that is discussing in evolutionary biology. In [1] the fitness of a colony of cells is considered in terms of its two basic components, viability and fecundity.…
A completeness conjecture is advanced concerning the free small-colimit completion P(A) of a (possibly large) category A. The conjecture is based on the existence of a small generating-cogenerating set of objects in A. We sketch how the…
This article is concerned with the existence of a weak solution to the initial boundary problem for a cross-diffusion system which arises in the study of two cell population growth. The mathematical challenge is due to the fact that the…
The revival mechanism in dormant bacteria is a puzzling and open issue. We propose a model of information diffusion on a regular grid where agents represent bacteria and their mutual interactions implement quorum sensing. Agents may have…
Free products of two residually finite groups with amalgamated retracts are considered. It is proved that a cyclic subgroup of such a group is not finitely separable if, and only if, it is conjugated with a subgroup of a free factor which…
A protocell model consisting of mutually catalyzing molecules is studied in order to investigate how chemical compositions are transferred recursively through cell divisions under replication errors. Depending on the path rate, the numbers…
We investigate the probability density of rescaled sums of iterates of deterministic dynamical systems, a problem relevant for many complex physical systems consisting of dependent random variables. A Central Limit Theorem (CLT) is only…
We study a two-species bidirectional exclusion process, and a single species variant, which is motivated by the motion of organelles and vesicles along microtubules. Specifically, we are interested in the clustering of the particles and…
The object of our investigation is a point that gives the maximum value of a potential with a strictly decreasing radially symmetric kernel. It defines a center of a body in Rm. When we choose the Riesz kernel or the Poisson kernel as the…
Self-cycling fermentation is an automated process used for culturing microorganisms. We consider a model of $n$ distinct species competing for a single non-reproducing nutrient in a self-cycling fermentor in which the nutrient level is used…
Like other types of computational research, modeling and simulation of biological processes (biomodels) is still largely communicated without sufficient detail to allow independent reproduction of results. But reproducibility in this area…
The metabolic network of a living cell involves several hundreds or thousands of interconnected biochemical reactions. Previous research has shown that under realistic conditions only a fraction of these reactions is concurrently active in…
We introduce a necessary and sufficient criterion for determining the existence and the values of ratio limits of complex sequences generated by arbitrary linear recurrences.
For understanding the origin of life, it is essential to explain the development of a compartmentalized structure, which undergoes growth and division, from a set of chemical reactions. In this study, a hypercycle with two chemicals that…
We analyze the interactions between division, mutation and selection in a simplified evolutionary model, assuming that the population observed can be classified into fitness levels. The construction of our mathematical framework is…
We investigate a generalization of stacks that we call $\mathcal{C}$-machines. We show how this viewpoint rapidly leads to functional equations for the classes of permutations that $\mathcal{C}$-machines generate, and how these systems of…