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Molecular phenotypes are important links between genomic information and organismic functions, fitness, and evolution. Complex phenotypes, which are also called quantitative traits, often depend on multiple genomic loci. Their evolution…

种群与进化 · 定量生物学 2015-06-12 Armita Nourmohammad , Stephan Schiffels , Michael Laessig

Over the past century, nonlinear difference and differential equations have been used to understand conditions for species coexistence. However, these models fail to account for random fluctuations due to demographic and environmental…

种群与进化 · 定量生物学 2019-02-12 Sebastian J. Schreiber

We consider a model for Darwinian evolution in an asexual population with a large but non-constant populations size characterized by a natural birth rate, a logistic death rate modelling competition and a probability of mutation at each…

概率论 · 数学 2015-08-28 Martina Baar , Anton Bovier , Nicolas Champagnat

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

概率论 · 数学 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

We investigate a simple quantitative genetics model subjet to a gradual environmental change from the viewpoint of the phylogenies of the living individuals. We aim to understand better how the past traits of their ancestors are shaped by…

概率论 · 数学 2021-04-22 Vincent Calvez , Benoît Henry , Sylvie Méléard , Viet Chi Tran

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

The role of the selection pressure and mutation amplitude on the behavior of a single-species population evolving on a two-dimensional lattice, in a periodically changing environment, is studied both analytically and numerically. The…

种群与进化 · 定量生物学 2009-11-13 Ioana Bena , Michel Droz , Janusz Szwabinski , Andrzej Pekalski

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

种群与进化 · 定量生物学 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

种群与进化 · 定量生物学 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

This contribution is concerned with mathematical models for the dynamics of the genetic composition of populations evolving under recombination. Recombination is the genetic mechanism by which two parent individuals create the mixed type of…

种群与进化 · 定量生物学 2011-01-12 Ellen Baake

We consider a stochastic individual-based population model with competition, trait-structure affecting reproduction and survival, and changing environment. The changes of traits are described by jump processes, and the dynamics can be…

概率论 · 数学 2022-01-17 Benoît Henry , Sylvie Méléard , Viet Chi Tran

We present a model for the dynamics of a population of bacteria with a continuum of traits, who compete for resources and exchange horizontally (transfer) an otherwise vertically inherited trait with possible mutations. Competition…

We propose a mathematical framework for natural selection in finite populations. Traditionally, many of the selection-based processes used to describe cultural and genetic evolution (such as imitation and birth-death models) have been…

种群与进化 · 定量生物学 2015-11-18 Alex McAvoy

Molecular phenotypes link genomic information with organismic functions, fitness, and evolution. Quantitative traits are complex phenotypes that depend on multiple genomic loci. In this paper, we study the adaptive evolution of a…

种群与进化 · 定量生物学 2015-06-19 Torsten Held , Armita Nourmohammad , Michael Lässig

We are interested in a stochastic model of trait and age-structured population undergoing mutation and selection. We start with a continuous time, discrete individual-centered population process. Taking the large population and rare…

概率论 · 数学 2009-03-28 Sylvie Méléard , Viet Chi Tran

Populations evolving under the joint influence of recombination and resampling (traditionally known as genetic drift) are investigated. First, we summarise and adapt a deterministic approach, as valid for infinite populations, which assumes…

种群与进化 · 定量生物学 2009-02-20 Ellen Baake , Inke Herms

We consider an asexually reproducing population on a finite type space whose evolution is driven by exponential birth, death and competition rates, as well as the possibility of mutation at a birth event. On the individual-based level this…

种群与进化 · 定量生物学 2020-02-10 Anna Kraut , Anton Bovier

Populations are made up of an integer number of individuals and are subject to stochastic birth-death processes whose rates may vary in time. Useful quantities, like the chance of ultimate fixation, satisfy an appropriate difference…

种群与进化 · 定量生物学 2020-07-22 Jayant Pande , Nadav M. Shnerb

We are interested in the evolving genealogy of a birth and death process with trait structure and ecological interactions. Traits are hereditarily transmitted from a parent to its offspring unless a mutation occurs. The dynamics may depend…

概率论 · 数学 2012-06-20 Sylvie Méléard , Viet Chi Tran

Selection, mutation and random drift affect the dynamics of allele frequencies and consequently of quantitative traits. While the macroscopic dynamics of quantitative traits can be measured, the underlying allele frequencies are typically…

种群与进化 · 定量生物学 2016-03-15 Katarína Boďová , Gašper Tkačik , Nicholas H. Barton