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Evolution of the amino acid sequences of transthyretin (TTR) can provide additional information about its dynamics that both complements and extends the already extensive static structural data. Protein dynamics is largely driven by…

生物物理 · 物理学 2021-12-28 J. C. Phillips

We study self-contact phenomena in elastic rods that are constrained to lie on a cylinder. By choosing a particular set of variables to describe the rod centerline the variational setting is made particularly simple: the strain energy is a…

数学物理 · 物理学 2009-09-29 G. H. M. van der Heijden , M. A. Peletier , R. Planqué

Living organisms must respond to environmental changes. Generally, accurate and rapid responses are provided by simple, unidirectional networks that connect inputs with outputs. Besides accuracy and speed, biological responses should also…

分子网络 · 定量生物学 2021-09-01 Masayo Inoue , Kunihiko Kaneko

We present a generic framework for modelling three-dimensional deformable shells of active matter that captures the orientational dynamics of the active particles and hydrodynamic interactions on the shell and with the surrounding…

软凝聚态物质 · 物理学 2019-11-20 Luuk Metselaar , Julia M. Yeomans , Amin Doostmohammadi

This paper aims at a comprehensive understanding on the novel elastic property of double-stranded DNA (dsDNA) discovered very recently through single-molecule manipulation techniques. A general elastic model for double-stranded biopolymers…

软凝聚态物质 · 物理学 2009-10-31 Haijun Zhou , Yang Zhang , Zhong-can Ou-Yang

Viewed under a fluorescence microscope, the actomyosin cytoskeleton presents vivid streaks of lines together with persistent oscillatory waves. Using an active hydrodynamic approach, we show how a uniform distribution of single or mixture…

软凝聚态物质 · 物理学 2025-04-25 Ayan Roychowdhury , Saptarshi Dasgupta , Madan Rao

We introduce a coarse-grained model of DNA with bases modeled as rigid-body ellipsoids to capture their anisotropic stereochemistry. Interaction potentials are all physicochemical and generated from all-atom simulation/parameterization with…

软凝聚态物质 · 物理学 2015-05-14 Alex Morriss-Andrews , Joerg Rottler , Steven S. Plotkin

Exact string solutions are presented, where moduli fields are varying with time. They provide examples where a dynamical change of the topology of space is occurring. Some other solutions give cosmological examples where some dimensions are…

广义相对论与量子宇宙学 · 物理学 2014-11-17 E. Kiritsis , C. Kounnas

We use computer simulations and scaling arguments to investigate statistical and structural properties of a semiflexible ribbon composed of isosceles triangles. We study two different models, one where the bending energy is calculated from…

统计力学 · 物理学 2009-11-07 Boris Mergell , Mohammad R. Ejtehadi , Ralf Everaers

We investigate the stability and geometrically non-linear dynamics of slender rods made of a linear isotropic poroelastic material. Dimensional reduction leads to the evolution equation for the shape of the poroelastica where, in addition…

软凝聚态物质 · 物理学 2016-08-31 J. M. Skotheim , L. Mahadevan

Entangled networks of stiff biopolymers exhibit complex dynamic response, emerging from the topological constraints that neighboring filaments impose upon each other. We propose a class of reference models for entanglement dynamics of stiff…

软凝聚态物质 · 物理学 2008-06-23 Felix Höfling , Tobias Munk , Erwin Frey , Thomas Franosch

DNA looping is important in DNA condensation and regulation. One method for forming a DNA loop, thought to be used by the condensing agent protamine, is bind-and-bend. In bind-and-bend, molecules bind all along the DNA, each creating a bend…

生物物理 · 物理学 2023-11-06 Michael Liaofan Liu , Daniel W. Oo , Ryan B. McMillan , Ashley R. Carter

The control over DNA elongation in nanofluidic devices holds great potential for large-scale genomic analysis. So far, the manipulation of DNA in nanochannels has been mostly carried out with electrophoresis and seldom with hydrodynamics,…

We derive solutions of the Kirchhoff equations for a knot tied on an infinitely long elastic rod subjected to combined tension and twist. We consider the case of simple (trefoil) and double (cinquefoil) knots; other knot topologies can be…

经典物理 · 物理学 2015-05-13 N. Clauvelin , B. Audoly , S. Neukirch

We investigate experimentally and model the mechanical response of a soft Hookean ribbon submitted to large twist $\eta$ and longitudinal tension $T$, under clamped boundary conditions. We derive a formula for the torque $M$ using the \FvK…

软凝聚态物质 · 物理学 2019-05-01 Julien Chopin , Romildo T. D. Filho

Knots across various length scales, from micro to macro-scales, such as polymers, DNA, shoelaces, and surgery, serving their unique mechanical properties. The shape of ideal knots has been extensively studied in the context of knot theory,…

软凝聚态物质 · 物理学 2025-07-01 Taiki Goto , Shunsuke Nomura , Tomohiko G. Sano

This article proposes a model including thermal effects for closed supercoiled DNA. Existing models include an elastic rod. Euler's elastica, ideal elastic rods on a plane, have only two kinds of closed shapes, the circle and a…

软凝聚态物质 · 物理学 2022-01-05 Shigeki Matsutani , Emma Previato

Coupling between axial and torsional degrees of freedom often modifies the conformation and expression of natural and synthetic filamentous aggregates. Recent studies on chiral single-walled carbon nanotubes and B-DNA reveal a reversal in…

材料科学 · 物理学 2007-09-06 M. Upmanyu , H. L. Wang , H. Y. Liang , R. Mahajan

We study a LiCs strongly-interacting molecular gas loaded into an one-dimensional optical lattice at quarter filling. The molecules are in the lowest electronic and vibrational state, $X^{1}\Sigma$ ($\nu=0$). Due to the large intermolecular…

量子气体 · 物理学 2017-03-28 Vanessa Olaya-Agudelo , Karen Rodriguez

Transport of rodlike particles in confinement environments of macromolecular networks plays crucial roles in many important biological processes and technological applications. The relevant understanding has been limited to thin rods with…

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