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相关论文: Entropy loss in long-distance DNA looping

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The cross entropy loss is widely used due to its effectiveness and solid theoretical grounding. However, as training progresses, the loss tends to focus on hard to classify samples, which may prevent the network from obtaining gains in…

机器学习 · 计算机科学 2021-09-14 Barak Battash , Lior Wolf , Tamir Hazan

A unified model is constructed to study the recently observed DNA entropic elasticity, cooperative extensibility, and supercoiling property. With the introduction of a new structural parameter (the folding angle $\phi$), bending…

软凝聚态物质 · 物理学 2007-05-23 Zhou Haijun , Zhang Yang , Ou-Yang Zhong-can

In this work, building on state-of-the-art quantum Monte Carlo simulations, we perform systematic finite-size scaling of both entanglement and participation entropies for long-range Heisenberg chain with unfrustrated power-law decaying…

强关联电子 · 物理学 2025-01-08 Jiarui Zhao , Nicolas Laflorencie , Zi Yang Meng

The flexibility of short DNA chains is investigated via computation of the average correlation function between dimers which defines the persistence length. Path integration techniques have been applied to confine the phase space available…

软凝聚态物质 · 物理学 2018-10-19 Marco Zoli

Gel electrophoresis allows to separate knotted DNA (nicked circular) of equal length according to the knot type. At low electric fields, complex knots being more compact, drift faster than simpler knots. Recent experiments have shown that…

生物物理 · 物理学 2009-11-11 C. Weber , A. Stasiak , M. Fleurant , P. De Los Rios , G. Dietler

We characterize different cell states, related to cancer and ageing phenotypes, by a measure of entropy of network ensembles, integrating gene expression values and protein interaction networks. The entropy measure estimates the parameter…

分子网络 · 定量生物学 2013-05-24 G. Menichetti , G. Bianconi , E. Giampieri , G. Castellani , D. Remondini

The influence of tension on DNA looping has been studied both experimentally and theoretically in the past. However, different theoretical models have yielded different predictions, leaving uncertainty about their validity. We briefly…

统计力学 · 物理学 2025-01-17 Wout Laeremans , Wouter G Ellenbroek

We obtain the entropy of flexible linear chains composed of M monomers placed on the square lattice using a transfer matrix approach. An excluded volume interaction is included by considering the chains to be self-and mutually avoiding, and…

统计力学 · 物理学 2009-11-07 W. G. Dantas , J. F. Stilck

Entanglement entropy appears as a central property of quantum systems in broad areas of physics. However, its precise value is often sensitive to unknown microphysics, rendering it incalculable. By considering parametric dependence on…

高能物理 - 理论 · 物理学 2011-02-09 Mark P. Hertzberg , Frank Wilczek

The effect of electrostatic interactions on the stretching of DNA is investigated using a simple worm like chain model. In the limit of small force there are large conformational fluctuations which are treated using a self-consistent…

软凝聚态物质 · 物理学 2009-10-31 Namkyung Lee , D. Thirumalai

In local quantum field theory, the entanglement entropy of a region is divergent due to the arbitrary short-wavelength correlations near the boundary of the region. Quantum gravitational fluctuations are expected to cut off the entropy of…

高能物理 - 理论 · 物理学 2020-10-13 Usman Naseer

We discuss the entropy of a circular polymer under a topological constraint. We call it the {\it topological entropy} of the polymer, in short. A ring polymer does not change its topology (knot type) under any thermal fluctuations. Through…

统计力学 · 物理学 2009-11-07 Miyuki K. Shimamura , Tetso Deguchi

In this work we investigate the electronic transport along model DNA molecules using an effective tight-binding approach that includes the backbone on site energies. The localization length and participation number are examined as a…

介观与纳米尺度物理 · 物理学 2015-06-11 C. J. Páez , P. A. Schulz

A strict method is used to calculate the current-voltage characteristics of a double-stranded DNA. A more reliable model considering the electrostatic potential drop along an individual DNA molecular wire between the contacts is considered…

介观与纳米尺度物理 · 物理学 2007-05-23 Weihua Mu , Zhongcan Ou-Yang

We study electronic transport in long DNA chains using the tight-binding approach for a ladder-like model of DNA. We find insulating behavior with localizaton lengths xi ~ 25 in units of average base-pair seperation. Furthermore, we observe…

软凝聚态物质 · 物理学 2007-05-23 Antonio Rodriguez , Rudolf A. Roemer , Matthew S. Turner

Loops are essential secondary structure elements in folded DNA and RNA molecules and proliferate close to the melting transition. Using a theory for nucleic acid secondary structures that accounts for the logarithmic entropy c ln m for a…

统计力学 · 物理学 2011-05-02 Thomas R. Einert , Henri Orland , Roland R. Netz

In this thesis, we provide an initial investigation into bounds for topological entropy of switched linear systems. Entropy measures, roughly, the information needed to describe the behavior of a system with finite precision on finite time…

最优化与控制 · 数学 2016-10-14 James Schmidt

How DNA repair enzymes find the relatively rare sites of damage is not known in great detail. Recent experiments and molecular data suggest that the individual repair enzymes do not work independently of each other, but rather interact with…

生物大分子 · 定量生物学 2007-05-23 Kasper Astrup Eriksen

Active loop extrusion - the process of formation of dynamically growing chromatin loops due to the motor activity of DNA-binding protein complexes - is firmly established mechanism responsible for chromatin spatial organization at different…

统计力学 · 物理学 2023-01-11 Sergey Belan , Vladimir Parfenyev

In this comment we argue that while the conclusions in the original paper (Y. Kafri, D. Mukamel and L. Peliti, Phys. Rev. Lett. 85, 4988 (2000)) are correct for asymptotically long DNA chains, they do not apply to the chains used in typical…

统计力学 · 物理学 2013-01-24 Andreas Hanke , Ralf Metzler