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The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions…

偏微分方程分析 · 数学 2009-11-11 Carlos Escudero

In this paper, we propose and study a stochastic aggregation-diffusion equation of the Keller-Segel (KS) type for modeling the chemotaxis in dimensions $d=2,3$. Unlike the classical deterministic KS system, which only allows for…

偏微分方程分析 · 数学 2020-09-23 Hui Huang , Jinniao Qiu

We introduce stochastic models of chemotaxis generalizing the deterministic Keller-Segel model. These models include fluctuations which are important in systems with small particle numbers or close to a critical point. Following Dean's…

统计力学 · 物理学 2009-09-01 Pierre-Henri Chavanis

Chemotaxis systems of Keller--Segel type constitute one of the central mathematical frameworks for understanding aggregation phenomena in biological and ecological systems. Over the past decades, the theory has evolved from the classical…

偏微分方程分析 · 数学 2026-03-06 Kolade M Owolabi , Eben Mare , Clara O Ijalana , Kolawole S Adegbie

Simulations are performed to investigate the nonlinear dynamics of a (2+1)-dimensional chemotaxis model of Keller-Segel (KS) type with a logistic growth term. Because of its ability to display auto-aggregation, the KS model has been widely…

生物物理 · 物理学 2011-11-14 S. Banerjee , A. P. Misra , L. Rondoni

This paper is concerned with numerical approximation of some two-dimensional Keller-Segel chemotaxis models, especially those generating pattern formations. The numerical resolution of such nonlinear parabolic-parabolic or…

数值分析 · 数学 2020-10-29 M. Benzakour Amine

We are concerned with the hyperbolic Keller-Segel model with quorum sensing, a model describing the collective cell movement due to chemical signalling with a flux limitation for high cell densities. This is a first order quasilinear…

偏微分方程分析 · 数学 2007-05-23 Benoit Perthame , Anne-Laure Dalibard

Extended systems governed by partial differential equations can, under suitable conditions, be approximated by means of sets of ordinary differential equations for global quantities capturing the essential features of the systems dynamics.…

定量方法 · 定量生物学 2015-06-18 Juan Belmonte-Beitia , Gabriel F. Calvo , Victor M. Perez-Garcia

We present a discrete model of chemotaxis whereby cells responding to a chemoattractant are seen as individual agents whose movement is described through a set of rules that result in a biased random walk. In order to take into account…

偏微分方程分析 · 数学 2020-03-27 Federica Bubba , Tommaso Lorenzi , Fiona R Macfarlane

The aim of this paper is to provide the analysis result for the partial differential equations arising from the rigorous derivation of the degenerate parabolic-elliptic Keller-Segel system from a moderately interacting stochastic particle…

偏微分方程分析 · 数学 2023-01-20 Li Chen , Veniamin Gvozdik , Yue Li

The Keller--Segel PDE is a model for chemotaxis known to exhibit possible finite-time blow-up. Following a seminal work by Tello and Winkler, a logistic damping term is added in this PDE and local well-posedness of mild solutions is proven.…

概率论 · 数学 2025-12-24 Thomas Cavallazzi , Alexandre Richard , Milica Tomasevic

We analyze the existence, linear stability, and slow dynamics of localized 1D spike patterns for a Keller--Segel model of chemotaxis that includes the effect of logistic growth of the cellular population. Our analysis of localized patterns…

偏微分方程分析 · 数学 2023-08-01 Fanze Kong , Michael Ward , Juncheng Wei

We develop a new four-phase tumor growth model with angiogenesis, derived from a diffuse-interface mixture model composed by a viable, a necrotic, a liquid and an angiogenetic component, coupled with two massless chemicals representing a…

数值分析 · 数学 2022-03-07 Abramo Agosti , Alice Giotta Lucifero , Sabino Luzzi

We study a regularized interacting particle method for computing aggregation patterns and near singular solutions of a Keller-Segal (KS) chemotaxis system in two and three space dimensions, then further develop DeepParticle (DP) method to…

计算物理 · 物理学 2024-01-30 Zhongjian Wang , Jack Xin , Zhiwen Zhang

This paper considers the Keller-Segel model coupled to stochastic Navier-Stokes equations (KS-SNS, for short), which describes the dynamics of oxygen and bacteria densities evolving within a stochastically forced 2D incompressible viscous…

偏微分方程分析 · 数学 2024-08-02 Lei Zhang , Bin Liu

Personalized medicine based on medical images, including predicting future individualized clinical disease progression and treatment response, would have an enormous impact on healthcare and drug development, particularly for diseases (e.g.…

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of chemotaxis into account. The system describing the evolution…

最优化与控制 · 数学 2023-09-19 Gianni Gilardi , Andrea Signori , Jürgen Sprekels

The Keller-Segel system describes the collective motion of cells that are attracted by a chemical substance and are able to emit it. In its simplest form, it is a conservative drift-diffusion equation for the cell density coupled to an…

偏微分方程分析 · 数学 2010-10-29 Adrien Blanchet , Jean Dolbeault , Miguel Escobedo , Javier Fernández

The Keller-Segel system has been widely proposed as a model for bacterial waves driven by chemotactic processes. Current experiments on {\em E. coli} have shown precise structure of traveling pulses. We present here an alternative…

We investigate nonlinear dynamics near an unstable constant equilibrium in the classical Keller-Segel model. Given any general perturbation of magnitude $\delta$, we prove that its nonlinear evolution is dominated by the corresponding…

偏微分方程分析 · 数学 2007-05-23 Yan Guo , Hyung Ju Hwang
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