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Topological data analysis (TDA) is an active field of mathematics for quantifying shape in complex data. Standard methods in TDA such as persistent homology (PH) are typically focused on the analysis of data consisting of a single entity…

Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori information. Classically, different phases and phase…

定量方法 · 定量生物学 2021-01-19 Dhananjay Bhaskar , William Y. Zhang , Ian Y. Wong

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

This paper concerns a theoretical approach that combines topological data analysis (TDA) and sheaf theory. Topological data analysis, a rising field in mathematics and computer science, concerns the shape of the data and has been proven…

计算机视觉与模式识别 · 计算机科学 2020-12-04 Chuan-Shen Hu , Yu-Min Chung

Persistent homology (PH) is a method used in topological data analysis (TDA) to study qualitative features of data that persist across multiple scales. It is robust to perturbations of input data, independent of dimensions and coordinates,…

Over the last two decades, topological data analysis (TDA) has emerged as a very powerful data analytic approach which can deal with various data modalities of varying complexities. One of the most commonly used tools in TDA is persistent…

统计方法学 · 统计学 2025-12-08 Anass El Yaagoubi Bourakna , Moo K. Chung , Hernando Ombao

In topological data analysis (TDA), one often studies the shape of data by constructing a filtered topological space, whose structure is then examined using persistent homology. However, a single filtered space often does not adequately…

代数拓扑 · 数学 2023-03-14 Magnus Bakke Botnan , Michael Lesnick

Topological methods can provide a way of proposing new metrics and methods of scrutinising data, that otherwise may be overlooked. In this work, a method of quantifying the shape of data, via a topic called topological data analysis will be…

机器学习 · 统计学 2022-09-25 Tristan Gowdridge , Nikolaos Dervilis , Keith Worden

Topological data analysis (TDA) is an area of data science that focuses on using invariants from algebraic topology to provide multiscale shape descriptors for geometric data sets such as point clouds. One of the most important such…

计算几何 · 计算机科学 2023-06-21 David Loiseaux , Mathieu Carrière , Andrew J. Blumberg

Spatial transcriptomics (ST) measures gene expression at a set of spatial locations in a tissue. Communities of nearby cells that express similar genes form \textit{spatial domains}. Specialized ST clustering algorithms have been developed…

定量方法 · 定量生物学 2025-11-12 Perry Beamer , Zixuan Cang

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

定量方法 · 定量生物学 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Topological Data Analysis (TDA) offers a suite of computational tools that provide quantified shape features in high dimensional data that can be used by modern statistical and predictive machine learning (ML) models. In particular,…

密码学与安全 · 计算机科学 2023-07-06 Dominic Gold , Koray Karabina , Francis C. Motta

Topological data analysis (TDA) is a tool from data science and mathematics that is beginning to make waves in environmental science. In this work, we seek to provide an intuitive and understandable introduction to a tool from TDA that is…

机器学习 · 计算机科学 2025-07-15 Lander Ver Hoef , Henry Adams , Emily J. King , Imme Ebert-Uphoff

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics data. Topological data analysis (TDA) provides a way of…

基因组学 · 定量生物学 2024-04-23 Davide Gurnari , Aldo Guzmán-Sáenz , Filippo Utro , Aritra Bose , Saugata Basu , Laxmi Parida

Persistent Homology (PH) is a fundamental tool in computational topology, designed to uncover the intrinsic geometric and topological features of data across multiple scales. Originating within the broader framework of Topological Data…

代数拓扑 · 数学 2025-05-13 Aurelie Jodelle Kemme , Collins Amburo Agyingi

Topological Data Analysis (TDA) is a novel statistical technique, particularly powerful for the analysis of large and high dimensional data sets. Much of TDA is based on the tool of persistent homology, represented visually via persistence…

应用统计 · 统计学 2017-11-07 Sarit Agami , Robert J. Adler

Information networks are becoming increasingly popular to capture complex relationships across various disciplines, such as social networks, citation networks, and biological networks. The primary challenge in this domain is measuring…

代数拓扑 · 数学 2019-07-23 Mehmet Emin Aktas , Esra Akbas , Ahmed El Fatmaoui

The study of irreducible higher-order interactions has become a core topic of study in complex systems. Two of the most well-developed frameworks, topological data analysis and multivariate information theory, aim to provide formal tools…

信息论 · 计算机科学 2025-04-15 Thomas F. Varley , Pedro A. M. Mediano , Alice Patania , Josh Bongard

Understanding the behavior and evolution of a dynamical many-body system by analyzing patterns in their experimentally captured images is a promising method relevant for a variety of living and non-living self-assembled systems. The arrays…

An Important tool in the field topological data analysis is known as persistent Homology (PH) which is used to encode abstract representation of the homology of data at different resolutions in the form of persistence diagram (PD). In this…

图像与视频处理 · 电气工程与系统科学 2022-07-13 Aras Asaad , Dashti Ali , Taban Majeed , Rasber Rashid
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