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A simple spatial computer simulation model was recently introduced to study the evolution of the linguistic diversity. The model considers processes of selective geographic colonization, linguistic anomalous diffusion and mutation. In the…

物理与社会 · 物理学 2009-11-11 Viviane M. de Oliveira , Paulo R. A. Campos , Marcelo A. F. Gomes , Ing Ren Tsang

We investigate the effect of spatial range expansions on the evolution of fitness when beneficial and deleterious mutations co-segregate. We perform individual-based simulations of a uniform linear habitat and complement them with…

种群与进化 · 定量生物学 2013-06-10 Stephan Peischl , Isabelle Dupanloup , Mark Kirkpatrick , Laurent Excoffier

We study the wave solutions for a degenerated reaction diffusion system arising from the invasion of cells. We show that there exists a family of waves for the wave speed larger than or equals a certain number, and below which there is no…

动力系统 · 数学 2013-01-17 Xiaojie Hou

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model…

偏微分方程分析 · 数学 2020-06-30 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

The margins within the geographic range of species are often specific in terms of ecological and evolutionary processes, and can strongly influence the species' reaction to climate change. One of the frequently observed features at range…

种群与进化 · 定量生物学 2020-02-28 R. Juhász , B. Oborny

We introduce a free boundary model to example the effect of vesicle transport onto neurite growth. It consists of systems of drift-diffusion equations describing the evolution of the density of antero- and retrograde vesicles in each…

偏微分方程分析 · 数学 2025-11-26 Greta Marino , Jan-Frederik Pietschmann , Max Winkler

We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. The authors have justified the well-posedness of this problem and have…

偏微分方程分析 · 数学 2023-04-24 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

偏微分方程分析 · 数学 2013-06-11 Martin Kohlmann

In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…

偏微分方程分析 · 数学 2022-05-25 Slah Eddin Ben Abdeljalil , Atef Ben Essid , Saloua Mani Aouadi

The complexity of gene regulatory networks in multicellular organisms makes interpretable low-dimensional models highly desirable. An attractive geometric picture, attributed to Waddington, visualizes the differentiation of a cell into…

生物物理 · 物理学 2024-12-12 Gautam Reddy

This paper investigates the incompressible limit of a system modelling the growth of two cells population. The model describes the dynamics of cell densities, driven by pressure exclusion and cell proliferation. It has been shown that…

偏微分方程分析 · 数学 2019-01-08 P. Degond , S. Hecht , N. Vauchelet

We consider a population spreading across a finite number of sites. Individuals can move from one site to the other according to a network (oriented links between the sites) that vary periodically over time. On each site, the population…

动力系统 · 数学 2026-03-02 Michel Benaïm , Claude Lobry , Tewfik Sari , Edouard Strickler

An organism that is newly introduced into an existing population has a survival probability that is dependent on both the population density of its environment and the competition it experiences with the members of that population.…

种群与进化 · 定量生物学 2024-12-17 Jason M. Gray , Rowan J. Barker-Clarke , Jacob G. Scott , Michael Hinczewski

This paper proposes a model for the growth two interacting populations of cells that do not mix. The dynamics is driven by pressure and cohesion forces on the one hand and proliferation on the other hand. Following earlier works on the…

细胞行为 · 定量生物学 2018-04-12 Alina Chertock , Pierre Degond , Sophie Hecht , Jean-Paul Vincent

In this paper, we first consider two scalar nonlocal diffusion problems with a free boundary and a fixed boundary. We obtain the global existence, uniqueness and longtime behaviour of solution of these two problems. The spreading-vanishing…

偏微分方程分析 · 数学 2021-05-28 Lei Li , Mingxin Wang

Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…

偏微分方程分析 · 数学 2023-11-01 Xu'an Dou , Chengfeng Shen , Zhennan Zhou

Geographic ranges of communities of species evolve in response to environmental, ecological, and evolutionary forces. Understanding the effects of these forces on species' range dynamics is a major goal of spatial ecology. Previous…

种群与进化 · 定量生物学 2022-02-02 Farshad Shirani , Judith R. Miller

We present a novel mathematical model of heterogeneous cell proliferation where the total population consists of a subpopulation of slow-proliferating cells and a subpopulation of fast-proliferating cells. The model incorporates two…

细胞行为 · 定量生物学 2021-11-04 Sean T. Vittadello , Scott W. McCue , Gency Gunasingh , Nikolas K. Haass , Matthew J. Simpson

We address a novel approach for stochastic individual-based modelling of a single species population. Individuals are distinguished by their remaining lifetimes, which are regulated by the interplay between the inexorable running of time…

种群与进化 · 定量生物学 2021-01-08 Luis R. T. Neves , Leonardo Paulo Maia

We study a class of elliptic competition-diffusion systems of long range segregation models for two and more competing species. The existence and uniqueness of the solution are shown. We prove that as the competition rate goes to infinity…

偏微分方程分析 · 数学 2017-11-07 Farid Bozorgnia