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Typing methods are widely used in the surveillance of infectious diseases, outbreaks investigation and studies of the natural history of an infection. And their use is becoming standard, in particular with the introduction of High…

数据结构与算法 · 计算机科学 2020-06-16 Cátia Vaz , Marta Nascimento , João A. Carriço , Tatiana Rocher , Alexandre P. Francisco

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of non-treelike evolutionary events, like recombination, hybridization, or lateral gene transfer. In this paper, we present and study a new…

种群与进化 · 定量生物学 2007-08-28 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

Phylogenetics is the study of the evolutionary relationships between organisms. One of the main challenges in the field is to take biological data for a group of organisms and to infer an evolutionary tree, a graph that represents these…

种群与进化 · 定量生物学 2019-06-05 Elizabeth Gross , Colby Long , Joseph Rusinko

Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history and numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains…

Phylogenetic networks extend phylogenetic trees to allow for modeling reticulate evolutionary processes such as hybridization. They take the shape of a rooted, directed, acyclic graph, and when parameterized with evolutionary parameters,…

种群与进化 · 定量生物学 2018-08-28 R. A. L. Elworth , H. A. Ogilvie , J. Zhu , L. Nakhleh

As whole genomes become widely available, maximum likelihood and Bayesian phylogenetic methods are demonstrating their limits in meeting the escalating computational demands. Conversely, distance-based phylogenetic methods are efficient,…

种群与进化 · 定量生物学 2025-02-07 Matthew J. Penn , Neil Scheidwasser , Mark P. Khurana , Christl A. Donnelly , David A. Duchêne , Samir Bhatt

We present an efficient phylogenetic reconstruction algorithm allowing insertions and deletions which provably achieves a sequence-length requirement (or sample complexity) growing polynomially in the number of taxa. Our algorithm is…

概率论 · 数学 2013-02-25 Constantinos Daskalakis , Sebastien Roch

In NeuroEvolution, the topologies of artificial neural networks are optimized with evolutionary algorithms to solve tasks in data regression, data classification, or reinforcement learning. One downside of NeuroEvolution is the large amount…

神经与进化计算 · 计算机科学 2019-02-12 Jörg Stork , Martin Zaefferer , Thomas Bartz-Beielstein

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

种群与进化 · 定量生物学 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Evolutionary relationships between species are usually inferred through phylogenetic analysis, which provides phylogenetic trees computed from allelic profiles built by sequencing specific regions of the sequences and abstracting them to…

数据结构与算法 · 计算机科学 2021-01-01 Luana Silva

Historical linguistics aims at inferring the most likely language phylogenetic tree starting from information concerning the evolutionary relatedness of languages. The available information are typically lists of homologous (lexical,…

物理与社会 · 物理学 2015-05-27 Simone Pompei , Vittorio Loreto , Francesca Tria

Phylogenetic inference-the derivation of a hypothesis for the common evolutionary history of a group of species- is an active area of research at the intersection of biology, computer science, mathematics, and statistics. One assumes the…

种群与进化 · 定量生物学 2016-06-21 Ruth Davidson , Joseph Rusinko , Zoe Vernon , Jing Xi

The advances in variational inference are providing promising paths in Bayesian estimation problems. These advances make variational phylogenetic inference an alternative approach to Markov Chain Monte Carlo methods for approximating the…

种群与进化 · 定量生物学 2023-09-12 Amine M. Remita , Golrokh Vitae , Abdoulaye Baniré Diallo

Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…

种群与进化 · 定量生物学 2022-07-27 Brandon Legried , Sebastien Roch

Phylogenetic networks are notoriously difficult to reconstruct. Here we suggest that it can be useful to view unknown genetic distance along edges in phylogenetic networks as analogous to unknown resistance in electric circuits. This…

组合数学 · 数学 2020-10-01 Stefan Forcey , Drew Scalzo

The reconstruction of phylogenetic networks is an important but challenging problem in phylogenetics and genome evolution, as the space of phylogenetic networks is vast and cannot be sampled well. One approach to the problem is to solve the…

种群与进化 · 定量生物学 2023-04-14 Louxin Zhang , Niloufar Abhari , Caroline Colijn , Yufeng Wu

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

种群与进化 · 定量生物学 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

We investigate the dependence of the approximation capacity of deep residual networks on its depth in a continuous dynamical systems setting. This can be formulated as the general problem of quantifying the minimal time-horizon required to…

机器学习 · 计算机科学 2026-03-19 Jingpu Cheng , Qianxiao Li , Ting Lin , Zuowei Shen

Phylogenetic networks provide a framework for representing evolutionary histories involving reticulate events such as hybridization or horizontal gene transfer. A central problem is to infer such networks from local structural information.…

离散数学 · 计算机科学 2026-05-12 Patricia A. Ebert , Marc Hellmuth

The inference of phylogenetic networks, which model complex evolutionary processes including hybridization and gene flow, remains a central challenge in evolutionary biology. Until now, statistically consistent inference methods have been…

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