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The United Nations Joint Programme on HIV/AIDS (UNAIDS) has set a target to ensure that 15 million HIV-positive people in the world would be receiving combination anti-retroviral treatment (ART) by 2015. This target is likely to be reached…

定量方法 · 定量生物学 2014-06-27 Brian G. Williams

A rich literature has explored the modeling of homophily and other forms of nonuniform mixing associated with individual-level covariates within the exponential family random graph (ERGM) framework. Such differential mixing does not fully…

社会与信息网络 · 计算机科学 2019-08-06 Francis Lee , Carter T. Butts

Estimating HIV-1 incidence using biomarker assays in cross-sectional surveys is important for understanding the HIV pandemic. However, the utility of these estimates has been limited by uncertainty about what input parameters to use for…

The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the…

种群与进化 · 定量生物学 2012-08-01 Richard A. Neher , Thomas Leitner

For many health conditions, there are highly efficacious treatment and prevention products. Maximizing their impact requires strategies that improve the reach of health screening in order to establish who could benefit. For example, HIV…

AIDS is the pandemic of our era. A disease that scares us not only because it is fatal but also because its insidious time course makes us all potential carriers long before it hands us our heads in a basket. The strange three stage…

适应与自组织系统 · 物理学 2009-10-31 Uri Hershberg , Yoram Louzoun , Henri Atlan , Sorin Solomon

This study presents an approach to analyze health disparities in Sexual and Gender Minority (SGM) populations, with a focus on the role of social support levels as an example to allow causal interpretations of regression models. We advocate…

应用统计 · 统计学 2024-05-07 Junjie Lu , Zhongyi Guo , David H. Rehkopf

Objective: The reservoir of human immunodeficiency virus (HIV) latently infected cells is the major obstacle for eradication of acquired immunodeficiency syndrome (AIDS). Due to the noisy environment and multiple influencing factors in the…

生物物理 · 物理学 2024-11-06 Ruiqi Xiong , Yang Su , Ping Ao

Longitudinal cohorts to determine the incidence of HIV infection are logistically challenging, so researchers have sought alternative strategies. Recency test methods use biomarker profiles of HIV-infected subjects in a cross-sectional…

统计方法学 · 统计学 2022-01-13 Fei Gao , Marlena S. Bannick

Introduction: The value of integrating federal HIV services data with HIV surveillance is currently unknown. Upstream and complete case capture is essential in preventing future HIV transmission. Methods: This study integrated Ryan White,…

机器学习 · 计算机科学 2023-04-21 Nick Williams

As the global HIV pandemic enters its fourth decade, increasing numbers of surveillance sites have been established which allows countries to look into the epidemics at a finer scale, e.g. at sub-national level. However, the epidemic models…

应用统计 · 统计学 2014-11-18 Le Bao , Mary Mahy , Xiaoyue Niu , Tim Brown , Peter Ghys

Social context plays an important role in perpetuating or reducing HIV risk behaviors. This study analyzed the network and individual attributes that were associated with the likelihood that people who inject drugs (PWID) will engage in HIV…

The OraQuick In-Home HIV self-test represents a fast, inexpensive, and convenient method for users to assess their HIV status. If integrated thoughtfully into existing testing practices, accompanied by efficient pathways to formal…

种群与进化 · 定量生物学 2024-04-08 Alex Viguerie , Chaitra Gopalappa , Cynthia M. Lyles , Paul G. Farnham

Using the introduction of comprehensive sex education in Sweden as a natural experiment, we explore how educational curricula can shape social norms and impact personal well-being. Inspired by liberal values, the curriculum taught more than…

综合经济学 · 经济学 2026-02-19 Volha Lazuka , Annika Elwert

Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy…

应用统计 · 统计学 2020-09-03 Zhou Lan , Le Bao

Tuberculosis (TB) and human immunodeficiency virus (HIV) can be considered a deadly human syndemic. In this article, we formulate a model for TB and HIV transmission dynamics. The model considers both TB and acquired immune deficiency…

动力系统 · 数学 2014-07-15 Cristiana J. Silva , Delfim F. M. Torres

With the launch of second line anti-retroviral therapy for HIV infected individuals, there has been an increased expectation on surviving period of people with HIV. We consider previously well-known models in HIV epidemiology where the…

定量方法 · 定量生物学 2021-06-15 Arni S. R. Srinivasa Rao

Safe and effective preventive vaccines have the potential to help stem the HIV epidemic. The efficacy of such vaccines is typically measured in randomized, double-blind phase IIb/III trials and described as a reduction in newly acquired HIV…

统计方法学 · 统计学 2024-10-10 Yutong Jin , Alex Luedtke , Zoe Moodie , Holly Janes , David Benkeser

In the pool of people seeking partners, a uniformly greater preference for abstinence increases the prevalence of infection and worsens everyone's welfare. In contrast, prevention and treatment reduce prevalence and improve payoffs. The…

理论经济学 · 经济学 2019-05-07 Sander Heinsalu

Using a US nationally representative sample and a double list experiment designed to elicit views free from social desirability bias, we find that anti-transgender labor market attitudes are significantly underreported. After correcting for…

综合经济学 · 经济学 2022-09-07 Billur Aksoy , Christopher S. Carpenter , Dario Sansone