相关论文: Enhancing Mechanical Stimuli in Functionally Grade…
The optimization of porous infill structures via local volume constraints has become a popular approach in topology optimization. In some design settings, however, the iterative optimization process converges only slowly, or not at all even…
When stressed sufficiently, solid materials yield and deform plastically via reorganization of microscopic constituents. Indeed, it is possible to alter the micro-structure of materials by judicious application of stress, an empirical pro-…
Flow-induced shear stresses have been found to be a stimulatory factor in pre-osteoblastic cells seeded in 3D porous scaffolds and cultured under continuous flow perfusion. However, due to the complex internal structure of the scaffolds,…
Active matter studies are increasingly geared towards the high-density or glassy limit. This is mainly inspired by the remarkable resemblance between active glassy materials and conventional passive glassy matter. Interestingly, within this…
The strain-rate sensitivity of confined granular materials has been widely explored, with most findings exhibiting rate-strengthening behaviors. This study, however, reveals a distinct rate-softening behavior across a certain strain rate…
Rapid solidification in Additively Manufactured (AM) metallic materials results in the development of significant microscale internal stresses, which are attributed to the printing induced dislocation substructures. The resulting backstress…
In this paper, a non-uniform rational B-spline based iso-geometric finite element method is used to study the static and dynamic characteristics of functionally graded material (FGM) plates. The material properties are assumed to be graded…
Gradient porous structured materials possess significant potential of being applied in many engineering fields. To accelerate the design process of infill graded microstructures, a novel asymptotic homogenisation topology optimisation…
The main goal of this work is to clarify and quantify, by means of mathematical analysis, the role of structural viscoelasticity in the biomechanical response of deformable porous media with incompressible constituents to sudden changes in…
Neural prosthetics are typically situated in an aggressive, biochemical environment that requires materials with superior stability and performance. These probes have dual functionalities of recording and stimulation. The material stability…
A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells. Typical models of cell growth for…
In cultured meat (CM) products the paramount significance lies in the fundamental attributes like texture and sensory of the processed end product. To cater to the tactile and gustatory preferences of real meat, the product needs to be…
This study presents an extension of multiscale topology optimization by integrating both yield stress and local/global buckling considerations into the design process. Building upon established multiscale methodologies, we develop a new…
Physical properties of out of equilibrium soft materials depend on time as well as deformation history. In this work we propose to transform this major shortcoming into gain by applying controlled deformation field to tailor the rheological…
This paper presents fracture response of alkali-activated slag (AAS) mortars with up to 30% (by volume) of slag being replaced by waste iron powder which contains a significant fraction of elongated particles. The elongated iron particles…
Computational models have become an essential part of exploratory protocols in cell biology, as a complement to in vivo or in vitro experiments. These virtual models have the twofold advantage of enabling access to new types of data and…
Flow-induced failure of granular materials is relevant to a broad range of geomechanical applications. Plasticity, which is the inherent failure mechanism of most granular materials, enables large deformations that can invalidate linearised…
To solve large-scale or high-resolution topology optimization problem, a novel algorithm is developed based on modified bi-directional evolutionary structure optimization (BESO) and extended finite element method (XFEM). Within XFEM, a set…
The mechanical properties of biological materials are spatially heterogeneous. Typical tissues are made up of a spanning fibrous extracellular matrix in which various inclusions, such as living cells, are embedded. While the influence of…
Bone repair using BMP-2 is a promising therapeutic approach in clinical practices, however, high dosages required to be effective pose issues of cost and safety. The present study explores the potential of low dose BMP-2 treatment via…