用于改善神经假体中微电极性能的微加工参数调控
应用物理
2021-05-14 v2
摘要
神经假体通常处于具有侵蚀性的生化环境中，要求材料具备优异的稳定性和性能。这些探针具有记录与刺激的双重功能。材料稳定性由这些探针在数十亿次电调制循环中承受工作条件的能力来定义。另一方面，性能由微电极材料的电化学响应来衡量。本文制备并研究了以柔性衬底为支撑的两种材料体系（即铂和玻璃碳薄膜）制成的微电极，以探究工艺参数与神经接口电化学效能之间的关联。所得神经电极用于借助扫描电子显微镜和原子力显微镜研究铂和玻璃碳薄膜的工艺参数、表面形貌与拓扑结构之间的相互关系。结果表明，表面拓扑的变化和腐蚀速率相对于工艺参数的变化而变化。此外，结果揭示了表面粗糙度与腐蚀速率之间的一般趋势，即前者的增加或减少对应于后者的类似变化。
引用
@article{arxiv.1908.00892,
title = {Tuning of Microfabrication Parameters for Improving Performance of Microelectrodes in Neural Prosthetics},
author = {Nha Uyen Huynh and Sam Kassegne and George Youssef},
journal= {arXiv preprint arXiv:1908.00892},
year = {2021}
}
备注
(1) the phrase "due to higher potential" is somewhat vague in the context of the discussion stated; and (2) "Platinum may be superior for recording" is not confirmed, since no animal studies were performed. The literature has demonstrated that glassy carbon may perform better than platinum in vivo recording. This is based on actual animal experiments. Vomero et al, Scientific Reports, 2016