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The performance of risk prediction models is often characterized in terms of discrimination and calibration. The Receiver Operating Characteristic (ROC) curve is widely used for evaluating model discrimination. When evaluating the…

统计方法学 · 统计学 2021-10-19 Mohsen Sadatsafavi , Paramita Saha-Chaudhuri , John Petkau

The area under a receiver operating characteristic curve (AUC) is a useful tool to assess the performance of continuous-scale diagnostic tests on binary classification. In this article, we propose an empirical likelihood (EL) method to…

统计方法学 · 统计学 2022-05-05 Chul Moon , Xinlei Wang , Johan Lim

Estimating individualized treatment rules is a central task for personalized medicine. [zhao2012estimating] and [zhang2012robust] proposed outcome weighted learning to estimate individualized treatment rules directly through maximizing the…

统计方法学 · 统计学 2017-10-02 Yifan Cui , Ruoqing Zhu , Michael Kosorok

Adaptive Risk Control (ARC) is an online calibration strategy based on set prediction that offers worst-case deterministic long-term risk control, as well as statistical marginal coverage guarantees. ARC adjusts the size of the prediction…

机器学习 · 统计学 2024-10-11 Matteo Zecchin , Osvaldo Simeone

We propose a restricted win probability estimand for comparing treatments in a randomized trial with a time-to-event outcome. We also propose Bayesian estimators for this summary measure as well as the unrestricted win probability. Bayesian…

统计方法学 · 统计学 2024-11-06 Michelle Leeberg , Xianghua Luo , Thomas A. Murray

In recent years, there has been growing interest in causal machine learning estimators for quantifying subject-specific effects of a binary treatment on time-to-event outcomes. Estimation approaches have been proposed which attenuate the…

统计方法学 · 统计学 2026-03-30 Matthew Pryce , Karla Diaz-Ordaz , Ruth H. Keogh , Stijn Vansteelandt

Since survival data occur over time, often important covariates that we wish to consider also change over time. Such covariates are referred as time-dependent covariates. Quantile regression offers flexible modeling of survival data by…

统计方法学 · 统计学 2014-05-01 Malka Gorfine , Yair Goldberg , Yaacov Ritov

Feature screening is an important tool in analyzing ultrahigh-dimensional data, particularly in the field of Omics and oncology studies. However, most attention has been focused on identifying features that have a linear or monotonic impact…

统计方法学 · 统计学 2023-05-10 Yaxian Chen , KF Lam , Zhonghua Liu

In prevalent cohort studies with delayed entry, time-to-event outcomes are often subject to left truncation where only subjects that have not experienced the event at study entry are included, leading to selection bias. Existing methods for…

统计方法学 · 统计学 2025-12-25 Yuyao Wang , Andrew Ying , Ronghui Xu

What can be considered an appropriate statistical method for the primary analysis of a randomized clinical trial (RCT) with a time-to-event endpoint when we anticipate non-proportional hazards owing to a delayed effect? This question has…

统计方法学 · 统计学 2023-04-18 José L. Jiménez , Isobel Barrott , Francesca Gasperoni , Dominic Magirr

Predicting the risk of developing breast cancer is an important clinical tool to guide early intervention and tailoring personalized screening strategies. Early risk models have limited performance and recently machine learning-based…

图像与视频处理 · 电气工程与系统科学 2025-05-29 Zhengbo Zhou , Dooman Arefan , Margarita Zuley , Jules Sumkin , Shandong Wu

Receiver operating characteristic (ROC) curves are widely used as a measure of accuracy of diagnostic tests and can be summarized using the area under the ROC curve (AUC). Often, it is useful to construct a confidence intervals for the AUC,…

应用统计 · 统计学 2018-04-18 Hunyong Cho , Gregory J. Matthews , Ofer Harel

The Area Under the ROC Curve (AUC) is a widely employed metric in long-tailed classification scenarios. Nevertheless, most existing methods primarily assume that training and testing examples are drawn i.i.d. from the same distribution,…

机器学习 · 计算机科学 2023-11-07 Siran Dai , Qianqian Xu , Zhiyong Yang , Xiaochun Cao , Qingming Huang

Predicting the timing and occurrence of events is a major focus of data science applications, especially in the context of biomedical research. Performance for models estimating these outcomes, often referred to as time-to-event or survival…

统计方法学 · 统计学 2024-06-07 Ying Jin , Andrew Leroux

We extend recently proposed design-based capture-recapture (CRC) methods for prevalence estimation among registry participants, in order to enhance treatment effect evaluation among a trial-eligible target population. The so-called ``anchor…

统计方法学 · 统计学 2025-10-28 Lin Ge , Yuzi Zhang , Lance A. Waller , Robert H. Lyles

Background: Receiver Operating Characteristic (ROC) curves are widely used to evaluate the performance of Software Defect Prediction (SDP) models that estimate module fault-proneness, i.e., the probability that a module is faulty. A ROC…

软件工程 · 计算机科学 2026-04-23 Luigi Lavazza , Gabriele Rotoloni , Sandro Morasca

When choosing estimands and estimators in randomized clinical trials, caution is warranted as intercurrent events, such as - due to patients who switch treatment after disease progression, are often extreme. Statistical analyses may then…

应用统计 · 统计学 2023-03-13 Hege Michiels , An Vandebosch , Stijn Vansteelandt

Area under ROC curve (AUC) is a widely used performance measure for classification models. We propose two new distributionally robust AUC maximization models (DR-AUC) that rely on the Kantorovich metric and approximate the AUC with the…

最优化与控制 · 数学 2020-05-28 Wenbo Ma , Miguel A. Lejeune

Randomized Controlled Trials (RCT) are the current gold standards to empirically measure the effect of a new drug. However, they may be of limited size and resorting to complementary non-randomized data, referred to as observational, is…

统计方法学 · 统计学 2025-06-11 Ahmed Boughdiri , Julie Josse , Erwan Scornet

Left-truncated survival data commonly arise in prevalent cohort studies, where only individuals who have experienced disease onset and survived until enrollment in the study. When the onset process follows a stationary Poisson process, the…

统计方法学 · 统计学 2025-12-23 Jinwoo Lee , Donghwan Lee , Hyunwoo Lee , Jiyu Sun