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We propose a novel personalized concept for the optimal treatment selection for a situation where the response is a multivariate vector, that could contain right-censored variables such as survival time. The proposed method can be applied…

统计方法学 · 统计学 2022-10-03 Chathura Siriwardhana , K. B. Kulasekera , Somnath Datta

We report the development and validation of a data-driven real-time risk score that provides timely assessments for the clinical acuity of ward patients based on their temporal lab tests and vital signs, which allows for timely intensive…

机器学习 · 计算机科学 2017-05-23 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

In this paper we study covariance estimation with missing data. We consider missing data mechanisms that can be independent of the data, or have a time varying dependency. Additionally, observed variables may have arbitrary (non uniform)…

统计理论 · 数学 2021-06-17 Eduardo Pavez , Antonio Ortega

To facilitate early detection of breast cancer, there is a need to develop short-term risk prediction schemes that can prescribe personalized/individualized screening mammography regimens for women. In this study, we propose a new deep…

图像与视频处理 · 电气工程与系统科学 2024-12-05 Hong Hui Yeoh , Fredrik Strand , Raphaël Phan , Kartini Rahmat , Maxine Tan

Low-rank tensor models are widely used in statistics. However, most existing methods rely heavily on the assumption that data follows a sub-Gaussian distribution. To address the challenges associated with heavy-tailed distributions…

统计方法学 · 统计学 2025-09-16 Xiaoyu Zhang , Di Wang , Guodong Li , Defeng Sun

In the context of right-censored data, we study the problem of predicting the restricted time to event based on a set of covariates. Under a quadratic loss, this problem is equivalent to estimating the conditional Restricted Mean Survival…

统计理论 · 数学 2024-04-29 Ariane Cwiling , Vittorio Perduca , Olivier Bouaziz

The Receiver Operating Characteristic (ROC) is a well-established representation of the tradeoff between detection and false alarm probabilities in binary hypothesis testing. In many practical contexts ROC's are generated by thresholding a…

统计理论 · 数学 2020-12-16 Catherine Medlock , Alan Oppenheim

This paper addresses the problem of identifying and estimating the causal effect of a treatment in the presence of unmeasured confounding and various types of right-censoring. Examples of these censoring mechanisms are administrative…

统计理论 · 数学 2025-03-19 Ilias Willems , Sara Rutten , Gilles Crommen , Ingrid Van Keilegom

The area under the curve (AUC) of summary receiver operating characteristic (SROC) curve is a primary statistical outcome for meta-analysis of diagnostic test accuracy studies (DTA). However, its confidence interval has not been reported in…

应用统计 · 统计学 2022-08-02 Hisashi Noma , Yuki Matsushima , Ryota Ishii

In this paper, we establish weak consistency and asymptotic normality of an M-estimator of the regression function for left truncated and right censored (LTRC) model, where it is assumed that the observations form a stationary alpha-mixing…

统计理论 · 数学 2023-05-09 Hassiba Benseradj , Zohra Guessoum

Penalized logistic regression is extremely useful for binary classification with large number of covariates (higher than the sample size), having several real life applications, including genomic disease classification. However, the…

统计方法学 · 统计学 2023-04-10 Ayanendranath Basu , Abhik Ghosh , María Jaenada , Leandro Pardo

Risk stratification is most directly and informatively summarized as a risk distribution curve. From this curve the ROC curve, predictiveness curve, and other curves depicting risk stratification can be derived, demonstrating that they…

定量方法 · 定量生物学 2009-12-17 Ralph Stern

Covariate adjustment and methods of incorporating historical data in randomized clinical trials (RCTs) each provide opportunities to increase trial power. We unite these approaches for the analysis of RCTs with binary outcomes based on the…

统计方法学 · 统计学 2022-12-21 Alyssa M. Vanderbeek , Jessica L. Ross , David P. Miller , Alejandro Schuler

In this article, the analysis of left truncated and right censored competing risks data is carried out, under the assumption of the latent failure times model. It is assumed that there are two competing causes of failures, although most of…

统计方法学 · 统计学 2020-08-19 Debasis Kundu , Debanjan Mitra , Ayon Ganguly

This work is devoted to the analysis of the performance of energy detection based spectrum sensing in the presence of enriched fading conditions which are distinct for the large number of multipath components and the lack of a dominant…

In this paper we present a framework for risk-sensitive model predictive control (MPC) of linear systems affected by stochastic multiplicative uncertainty. Our key innovation is to consider a time-consistent, dynamic risk evaluation of the…

最优化与控制 · 数学 2018-04-26 Sumeet Singh , Yin-Lam Chow , Anirudha Majumdar , Marco Pavone

Tree methods (recursive partitioning) are a popular class of nonparametric methods for analyzing data. One extension of the basic tree methodology is the survival tree, which applies recursive partitioning to censored survival data. There…

统计方法学 · 统计学 2017-03-01 Wei Fu , Jeffrey S. Simonoff

Estimation of temporal counterfactual outcomes from observed history is crucial for decision-making in many domains such as healthcare and e-commerce, particularly when randomized controlled trials (RCTs) suffer from high cost or…

机器学习 · 计算机科学 2024-02-13 Chuizheng Meng , Yihe Dong , Sercan Ö. Arık , Yan Liu , Tomas Pfister

While meta-analyzing retrospective cancer patient cohorts, an investigation of differences in the expressions of target oncogenes across cancer subtypes is of substantial interest because the results may uncover novel tumorigenesis…

统计方法学 · 统计学 2023-07-03 Subharup Guha , David C. Christiani , S. V. Subramanian , Yi Li

Imagine a patient in critical condition. What and when should be measured to forecast detrimental events, especially under the budget constraints? We answer this question by deep reinforcement learning (RL) that jointly minimizes the…

机器学习 · 计算机科学 2019-06-11 Chun-Hao Chang , Mingjie Mai , Anna Goldenberg
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